Optimal Solution of the Fractional Order Breast Cancer Competition Model

This paper discusses the fractional order breast cancer competition model (F-BCCM), which considers population dynamics among cancer stem, tumor and healthy cells, as well as the effects of excess estrogen and the body’s natural immune response on the cell populations. Generalized shifted Legendre polynomials and their operational matrices are presented in the scope of a general procedure for the solution of the F-BCCM. The application of the Lagrange multipliers method transforms the F-BCCM into a system of algebraic equations. Additionally, the convergence analysis of the method and two illustrative numerical examples complement the study.Mathematics Subject Classification: 97M60; 41A58; 92C42.