A Study on Endometrial Histopathology of Women with Postmenopausal Bleeding in a Tertiary Care Centre, Kakinada, Andhra Pradesh

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Abstract

Introduction: Postmenopausal bleeding is bleeding from the reproductive system that occurs one year after menstrual periods have stopped. Bleeding from the genital tract occurring after the menopause is much more sinister than premenopausal bleeding. The main objectives in the diagnostic workup in postmenopausal women presenting with uterine bleeding is to detect or rule out endometrial cancer or atypical hyperplasia, further referred to as (pre) malignancy of the endometrium. Aims and Objectives: 1. To determine the causes of postmenopausal bleeding from endometrial histopathology. 2. To correlate between the histopathological report of endometrial biopsy and surgical specimen. 3. To evaluate the relation between age, parity, post-menopausal bleeding duration, endometrial thickness, uterine size, body mass index, and medical disorders in women presenting with postmenopausal bleeding versus the risk of endometrial hyperplasia and cancer. Methodology: This is a study, on histopathology of endometrium in postmenopausal bleeding women and its clinical correlation, undertaken in the department of obstetrics& gynecology over a period of 6 months. Results: 30 women presented with PMB out of which 3 were endometrial cancer, 13 cases were EH without atypia, 9 cases were EH with atypia and 5 cases of endometrial atrophy. Conclusion: In my study positive correlation was found with risk factors, in women with premalignant and malignant lesions.
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Introduction

Postmenopausal bleeding is bleeding from the reproductive system that occurs one year after menstrual periods have stopped. Bleeding from the genital tract occurring after the menopause is much more sinister than premenopausal bleeding. The main objectives in the diagnostic workup in postmenopausal women presenting with uterine bleeding is to detect or rule out endometrial cancer or atypical hyperplasia, further referred to as (pre) malignancy of the endometrium. Aims and Objectives: 1. To determine the causes of postmenopausal bleeding from endometrial histopathology. 2. To correlate between the histopathological report of endometrial biopsy and surgical specimen. 3. To evaluate the relation between age, parity, post-menopausal bleeding duration, endometrial thickness, uterine size, body mass index, and medical disorders in women presenting with postmenopausal bleeding versus the risk of endometrial hyperplasia and cancer. Methodology: This is a study, on histopathology of endometrium in postmenopausal bleeding women and its clinical correlation, undertaken in the department of obstetrics& gynecology over a period of 6 months. Results: 30 women presented with PMB out of which 3 were endometrial cancer, 13 cases were EH without atypia, 9 cases were EH with atypia and 5 cases of endometrial atrophy. Conclusion: In my study positive correlation was found with risk factors, in women with premalignant and malignant lesions.

Abstract

(English)

Introduction

Postmenopausal bleeding is bleeding from the reproductive system that occurs one year after menstrual periods have stopped. Bleeding from the genital tract occurring after the menopause is much more sinister than premenopausal bleeding. The main objectives in the diagnostic workup in postmenopausal women presenting with uterine bleeding is to detect or rule out endometrial cancer or atypical hyperplasia, further referred to as (pre) malignancy of the endometrium. Aims and Objectives: 1. To determine the causes of postmenopausal bleeding from endometrial histopathology. 2. To correlate between the histopathological report of endometrial biopsy and surgical specimen. 3. To evaluate the relation between age, parity, post-menopausal bleeding duration, endometrial thickness, uterine size, body mass index, and medical disorders in women presenting with postmenopausal bleeding versus the risk of endometrial hyperplasia and cancer. Methodology: This is a study, on histopathology of endometrium in postmenopausal bleeding women and its clinical correlation, undertaken in the department of obstetrics& gynecology over a period of 6 months. Results: 30 women presented with PMB out of which 3 were endometrial cancer, 13 cases were EH without atypia, 9 cases were EH with atypia and 5 cases of endometrial atrophy. Conclusion: In my study positive correlation was found with risk factors, in women with premalignant and malignant lesions. Files IJPCR,Vol16,Issue11,Article177.pdf Files (362.0 kB) | Name | Size | Download all | |---|---|---| | md5:32bf50cbc699412eb16f9e49df114e1b | 362.0 kB | Preview Download | Additional details Dates - Accepted - 2024-10-26 Software - Repository URL - http://impactfactor.org/PDF/IJPCR/16/IJPCR,Vol16,Issue11,Article177.pdf - Development Status - Active

References

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