Using Real-world data to Estimate the Changing Trends in the Prevalence and Incidence of type 2 Diabetes Mellitus in Xiamen of China,2014-2019

Abstract Background: The prevalence of diabetes is increasing worldwide. Our study aimed to estimate the changing trends in the prevalence and incidence of diagnosed type 2 diabetes mellitus (T2DM) among Xiamen residents and the floating population using real-world data. Method: We used real-world data from the System of Xiamen Citizens Health Information from 2014 to 2019 to estimate the changing trends in prevalence and incidence of diagnosed T2DM. The systems included the diagnosis of diabetes and the prescription of hypoglycemic drugs. Prevalent cases of T2DM were individuals who diagnosed T2DM and/or using hypoglycemic drugs. Incident cases were individuals with diagnosed T2DM and/or using hypoglycemic drugs in 2014 who had not diagnosed and/or no used one in the past. Results: In 2014 and 2019, the prevalence of T2DM in Xiamen was 4.04% and 4.84%, respectively. In 2014 and 2019, the incidence of T2DM in Xiamen was 1.41% and 1.50%, respectively. There was an increase significant in the total of the prevalence and incidence of T2DM in Xiamen (0.80% (95% CI 0.76%-0.83%, P <0.001; 0.09% (95% CI 0.07-0.11), P<0.001, respectively). The prevalence and incidence of T2DM in people aged 18-39 increased significantly, while the prevalence and incidence of T2DM in people aged 40-69 reduced significantly. Conclusions: We found that there was an increasingly significant in the total of the prevalence and incidence of T2DM in Xiamen from 2014 to 2019. The prevalence and incidence of T2DM in Xiamen were significantly increased and showed a trend of younger age.