Expression of β-actin in serum of patients with endometriosis

Objective:To detect β-actin in serum of patients with ovarian endometriosis cyst,and try to search new biomarkers as detection object for endometriosis in clinic.Methods:ELISA was used to detect the expression levels of serum β-actin in endometriosis group and control group,the related laboratory indexes were found by consulting the medical records.Results:Three experiments were conducted repeatedly among 40 specimens,the average content of serum β-actin in endometriosis group was statistically significantly higher than that in malignant ovarian cancer group(P0.05).After consulting medical records,the expression level of serum CA125 in ovarian endometriosis cyst was lower than that in malignant ovarian cancer.Conclusion:β-actin has a certain reference value for differentiating ovarian endometriosis from malignant ovarian cancer,and joint detection of β-actin and CAl25 can improve the specificity and sensitivity.