Development of a French version of the Endometriosis Health Profile 5 (EHP-5): cross-cultural adaptation and psychometric evaluation

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This study adapted and validated the French version of the Endometriosis Health Profile 5 (EHP-5), finding it to be a unidimensional, reliable, and valid instrument sensitive to endometriosis presence and severity.

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Abstract

PURPOSE: The Endometriosis Health Profile 5 (EHP-5) is a short version of an endometriosis-specific quality of life questionnaire. The objective of the study was to assess the psychometric validity of its French version. METHODS: A total of 125 patients with histologically proven endometriosis who underwent surgery for painful symptoms and 80 asymptomatic controls completed the EHP-5. Principal components analysis was performed to determine the dimensions of the instrument. Internal consistency was assessed using Cronbach's alpha. Construct validity was assessed by testing the relationship between the EHP-5 and the characteristics of endometriosis. RESULTS: For each item of EHP-5, endometriosis patients scored significantly higher than control women (p > 0.0001). Eleven items of the EHP-5 were unidimensional with excellent internal consistency (Cronbach's alpha = 0.92), and a summary aggregated index was then constructed. The EHP-5 index was sensitive to the presence of endometriosis, the type, location, severity of the disease, and pain or infertility as the main complaint with effect sizes ranging from 0.48 (95 % CI 0.11-0.85) for superficial endometriosis to 2.56 (95 % CI 2.18-2.93) for deeply infiltrating endometriosis. CONCLUSION: The French version of EHP-5 is valid and can be used for reporting patient-orientated outcome in future studies of French-speaking patients with endometriosis.
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Abstract

Purpose The Endometriosis Health Profile 5 (EHP-5) is a short version of an endometriosis-specific quality of life questionnaire. The objective of the study was to assess the psychometric validity of its French version.

Methods

A total of 125 patients with histologically proven endometriosis who underwent surgery for painful symptoms and 80 asymptomatic controls completed the EHP-5. Principal components analysis was performed to determine the dimensions of the instrument. Internal consistency was assessed using Cronbach’s alpha. Construct validity was assessed by testing the relationship between the EHP-5 and the characteristics of endometriosis.

Results

For each item of EHP-5, endometriosis patients scored significantly higher than control women (p > 0.0001). Eleven items of the EHP-5 were unidimensional with excellent internal consistency (Cronbach’s alpha = 0.92), and a summary aggregated index was then constructed. The EHP-5 index was sensitive to the presence of endometriosis, the type, location, severity of the disease, and pain or infertility as the main complaint with effect sizes ranging from 0.48 (95 % CI 0.11–0.85) for superficial endometriosis to 2.56 (95 % CI 2.18–2.93) for deeply infiltrating endometriosis.

Conclusion

The French version of EHP-5 is valid and can be used for reporting patient-orientated outcome in future studies of French-speaking patients with endometriosis.

References

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(2014). Laparoscopic treatment of endometriosis and effects on quality of life: A retrospective study using the short form EHP-5 endometriosis specific questionnaire. Journal of Obstetrics and Gynaecology, 34(4), 336–340. Acknowledgments This study was partly funded by the French public funding agency Délégation à la Recherche Clinique et à l’Innovation (DRCI), Versailles, France. Author information Authors and Affiliations Corresponding author Ethics declarations Conflict of interest All Authors declare that they no conflict of interest. Compliance with ethical standards All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. The 11th ethics research committee of Ile-de-France considered that our study involved no intervention and was thus exempt from the French statute on biomedical research (modified version of Law 2004-806, dated August 9, 2004). We complied with all French statutes concerning patient data, confidentiality, and restrictions. Appendix Appendix See Table 3. Rights and permissions About this article Cite this article Fauconnier, A., Huchon, C., Chaillou, L. et al. Development of a French version of the Endometriosis Health Profile 5 (EHP-5): cross-cultural adaptation and psychometric evaluation. Qual Life Res 26, 213–220 (2017). https://doi.org/10.1007/s11136-016-1346-y Accepted: Published: Issue date: DOI: https://doi.org/10.1007/s11136-016-1346-y

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Outcome instruments

EHP-30

Condition tags

endometriosisinfertility

MeSH descriptors

Cross-Cultural Comparison Endometriosis Psychometrics Quality of Life Adult Endometriosis Female France Humans Psychometrics Psychometrics Quality of Life Reproducibility of Results Surveys and Questionnaires Translating

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