Hiperplasia endometrial: una revisión narrativa sobre su patogénesis, factores de riesgo y diagnóstico.

In: Investigación Clínica · 2025 · vol. 66(1) , pp. 101–115 · doi:10.54817/ic.v66n1a09 · W4408347871
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This review analyzes the pathogenesis, risk factors, and diagnostic methods for endometrial hyperplasia, a precursor to endometrial carcinoma, considering its relationship with ovulatory disorders in reproductive years and factors like obesity and estrogen therapy in postmenopause.

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Abstract

Endometrial hyperplasia with or without atypia is a common gy-necological diagnosis and serve as precursor to endometrial carcinoma. During the reproductive years, the risk of developing endometrial hyperplasia is related to ovulatory disorders. In menopause and postmenopause, endometrial hyper-plasia is linked to factors such as obesity, estrogen replacement therapy, and others. This narrative study aims to review and analyze the pathogenesis, risk factors, and different diagnostic methods related to endometrial hyperplasia. The literature from 1970 and November 2024 was reviewed in the Latin Ameri-can and international bibliography using electronic databases such as Pub-Med, Google Scholar, Springer, the Cochrane Library, Embase, Scielo, Imbiomed-L, Redalyc, and Latindex, among others.

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