Clinical effect of uterine arterial embolization with polyvinyl alcohol and lipiodol-pingyangmycin emulsion in the uterine adenomyosis and leiomyoma

Objective To investigate the clinical effect of uterine arterial embolization with polyvinyl alcohol (PVA) and pingyangmycin-lipiodol emulsion (PLE) in the uterine leiomyoma and adenomyosis. Methods Twenty-eight patients with leiomyoma and adenomyosis diagnosed by ultrasound, DSA and clinical examination were divided into 2 groups. PVA particles and PLE were respectively used in 14 patients of each group. Microcatheters were applied in all cases. Followed-up period was 6 to 30 months. Results Technical success was achieved in all cases. Dysmenorrhea was disappeared in 8 cases of group A and 10 cases of group B 3 months after UAE, in 6 cases of group A and 4 cases of group B was dissolved at 5 months after UAE. The mean uterine volume reduction was 41.83 % and 43.59 % respectively at 6 months follow-up. The fibroid volume reduction in Group A and Group B was 51.63% and 52.9% respectively at 6 months follow-up. No severe complications happened. Conclusion Therapeutic effect of uterine arterial embolization with PVA or LPE has no significant difference in uterine adenomyosis and leiomyoma.