[The Gemeprost test in the screening of endometrial pathology]

Minerva ginecologica · 1991 · vol. 43(4) , pp. 181–4 · PMID:1857516 · W2410482344
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A randomized trial found intravaginal Gemeprost pre-operatively increased endometrial biopsy success rates and patient compliance by reducing pain compared to placebo.

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Abstract

A randomized clinical trial has been performed to evaluate the efficacy of intravaginal 1 mg Gemeprost for pre-operative cervical dilatation prior to vacuum aspiration and curettage for endometrial biopsy. Eighty-nine patients were evaluated, 51 treated with Gemeprost and 38 with placebo: in the first group biopsy was possible in 94% of cases vs 86% in the second group. Pain was significantly reduced with Gemeprost improving the success rate and the patient compliance.

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MeSH descriptors

Alprostadil Uterine Diseases Alprostadil Dilatation and Curettage Drug Evaluation Female Humans Placebos Prostaglandins E, Synthetic Uterine Diseases

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