Millisecond Magnetic Particle Imaging of a cerebral aneurysm phantom with and without flow diverter stent

Millisecond Magnetic Particle Imaging of a cerebral aneurysm phantom with and without flow diverter stent | Research Square window.SnipcartSettings = { analytics: { enabled: false } }; (function() { var accessVector = localStorage.getItem('access_vector') || ''; window.dataLayer = window.dataLayer || []; if (accessVector) { window.dataLayer.push({ user: { profile: { profileInfo: { snid: accessVector } } } }); } })(); (function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start':new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0],j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src='https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f);})(window,document,'script','dataLayer','GTM-K279D39R'); Browse Preprints In Review Journals COVID-19 Preprints AJE Video Bytes Research Tools Research Promotion AJE Professional Editing AJE Rubriq About Preprint Platform In Review Editorial Policies Our Team Advisory Board Help Center Sign In Submit a Preprint Cite Share Download PDF Article Millisecond Magnetic Particle Imaging of a cerebral aneurysm phantom with and without flow diverter stent Olaf Kosch, Augusto Sanches, Yigit Özpeynirci, Thomas Liebig, and 1 more This is a preprint; it has not been peer reviewed by a journal. https://doi.org/ 10.21203/rs.3.rs-7537820/v1 This work is licensed under a CC BY 4.0 License Status: Under Review Version 1 posted You are reading this latest preprint version Abstract Undetected, asymptomatic brain aneurysms include the high risk of progressive expansion, followed by rupture, hemorrhage and finally death in approximately 80% of the cases. Therefore, imaging techniques to assess the state of aneurysms and the success of the treatment of aneurysms are of high relevance. For this purpose, we manufactured artery phantoms with aneurysms by 3D silicon printing. Using MRI data sets including cerebral aneurysms that were specific to patients, the artery was created. By Magnetic Particle Imaging (MPI), we were able to resolve the location and movement of the tracer in the different parts of the artery phantom with millisecond resolution. To assess the success of treating aneurysms with flow diverter stents, we compared flow MPI measurements in a 3D-printed artery without a flow diverter stent with images in a treated artery with a flow diverter stent inside the vessel. Our results provide valuable information on the capabilities and prospects of MPI of vascular structures and the detection and quantification of flow changes in untreated and treated aneurysms for future in vivo applications. Physical sciences/Nanoscience and technology/Nanomedicine/Diagnostic devices Health sciences/Neurology/Neurological disorders/Cerebrovascular disorders/Stroke Full Text Additional Declarations There is NO Competing Interest. Cite Share Download PDF Status: Under Review Version 1 posted You are reading this latest preprint version Research Square lets you share your work early, gain feedback from the community, and start making changes to your manuscript prior to peer review in a journal. As a division of Research Square Company, we’re committed to making research communication faster, fairer, and more useful. We do this by developing innovative software and high quality services for the global research community. Our growing team is made up of researchers and industry professionals working together to solve the most critical problems facing scientific publishing. Also discoverable on Platform About Our Team In Review Editorial Policies Advisory Board Help Center Resources Author Services Accessibility API Access RSS feed Manage Cookie Preferences © Research Square 2026 | ISSN 2693-5015 (online) Privacy Policy Terms of Service Do Not Sell My Personal Information {"props":{"pageProps":{"initialData":{"identity":"rs-7537820","acceptedTermsAndConditions":true,"allowDirectSubmit":false,"archivedVersions":[],"articleType":"Article","associatedPublications":[],"authors":[{"id":523151102,"identity":"7cc272cf-4ed3-4c04-bd4a-eaf84d4e9517","order_by":0,"name":"Olaf 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