The impact of BMHV implantation angle on Left Ventricle hemodynamic characteristics

The impact of BMHV implantation angle on Left Ventricle hemodynamic characteristics | Research Square window.SnipcartSettings = { analytics: { enabled: false } }; (function() { var accessVector = localStorage.getItem('access_vector') || ''; window.dataLayer = window.dataLayer || []; if (accessVector) { window.dataLayer.push({ user: { profile: { profileInfo: { snid: accessVector } } } }); } })(); (function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start':new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0],j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src='https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f);})(window,document,'script','dataLayer','GTM-K279D39R'); Browse Preprints In Review Journals COVID-19 Preprints AJE Video Bytes Research Tools Research Promotion AJE Professional Editing AJE Rubriq About Preprint Platform In Review Editorial Policies Our Team Advisory Board Help Center Sign In Submit a Preprint Cite Share Download PDF Research Article The impact of BMHV implantation angle on Left Ventricle hemodynamic characteristics Zhixiong Li, Yan Qiang, Liang Qi, Jiabao Qi, Wenyu Geng, Yang Chen This is a preprint; it has not been peer reviewed by a journal. https://doi.org/ 10.21203/rs.3.rs-6438545/v1 This work is licensed under a CC BY 4.0 License Status: Posted Version 1 posted You are reading this latest preprint version Abstract Heart valve disease severely affects human health, and artificial heart valve replacement is currently the most effective treatment for valvular heart disease. The most widely used in clinical practice is the Bileaflet Mechanical Heart Valves (BMHV). This study constructs a three-dimensional model of the Left Ventricle (LV) and BMHV based on human medical imaging data and anatomical parameters. Dynamic modeling is conducted using computational fluid dynamics and bidirectional Fluid-Structure Interaction (FSI) to investigate the impact of different implantation angles of BMHV on the hemodynamic characteristics within the LV. This study primarily analyzes the effects of different implantation angles on the velocity distribution downstream of the BMHV and the vortex evolution patterns. It is found that when the valve is implanted in the AO (Anatomical position) direction, the blood flow exhibits strong penetration, high ejection efficiency, and lower energy consumption in the vortex evolution process, thereby improving blood flow efficiency. By analyzing the ridge distribution of the Finite Time Lyapunov Exponent (FTLE) field, it is observed that the AO implantation angle enhances blood flow transport, which helps reduce myocardial load and prolong the lifespan of both the valve and the myocardium. Therefore, when implanting the valve in patients, it should be positioned at the AO angle. This study provides a guiding framework for clinical treatment. Left Ventricle Bileaflet Mechanical Heart Valves Implantation Angle Hemodynamics Lagrangian Coherent Structure Full Text Additional Declarations No competing interests reported. Cite Share Download PDF Status: Posted Version 1 posted You are reading this latest preprint version Research Square lets you share your work early, gain feedback from the community, and start making changes to your manuscript prior to peer review in a journal. As a division of Research Square Company, we’re committed to making research communication faster, fairer, and more useful. We do this by developing innovative software and high quality services for the global research community. Our growing team is made up of researchers and industry professionals working together to solve the most critical problems facing scientific publishing. Also discoverable on Platform About Our Team In Review Editorial Policies Advisory Board Help Center Resources Author Services Accessibility API Access RSS feed Manage Cookie Preferences © Research Square 2026 | ISSN 2693-5015 (online) Privacy Policy Terms of Service Do Not Sell My Personal Information {"props":{"pageProps":{"initialData":{"identity":"rs-6438545","acceptedTermsAndConditions":true,"allowDirectSubmit":true,"archivedVersions":[],"articleType":"Research Article","associatedPublications":[],"authors":[{"id":448606978,"identity":"33aa845b-6a42-4c0f-be14-399d5936932a","order_by":0,"name":"Zhixiong Li","email":"","orcid":"","institution":"Lanzhou University of Technology","correspondingAuthor":false,"prefix":"","firstName":"Zhixiong","middleName":"","lastName":"Li","suffix":""},{"id":448606979,"identity":"dddb23b1-8ccc-464d-9c80-4b63ba4f4371","order_by":1,"name":"Yan 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The most widely used in clinical practice is the Bileaflet Mechanical Heart Valves (BMHV). This study constructs a three-dimensional model of the Left Ventricle (LV) and BMHV based on human medical imaging data and anatomical parameters. Dynamic modeling is conducted using computational fluid dynamics and bidirectional Fluid-Structure Interaction (FSI) to investigate the impact of different implantation angles of BMHV on the hemodynamic characteristics within the LV. This study primarily analyzes the effects of different implantation angles on the velocity distribution downstream of the BMHV and the vortex evolution patterns. It is found that when the valve is implanted in the AO (Anatomical position) direction, the blood flow exhibits strong penetration, high ejection efficiency, and lower energy consumption in the vortex evolution process, thereby improving blood flow efficiency. By analyzing the ridge distribution of the Finite Time Lyapunov Exponent (FTLE) field, it is observed that the AO implantation angle enhances blood flow transport, which helps reduce myocardial load and prolong the lifespan of both the valve and the myocardium. Therefore, when implanting the valve in patients, it should be positioned at the AO angle. 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