Clinical study on endometrial ovarian cyst treated by combined laparoscopy and chinese herbal medicine

Y Wu, Wu Y, Yuning Wu, Hua Ling, L Hua, Hua L, Yan Jin, Y Jin, Jin Yan, Jin Y, Xiaohui Zhang, Tong-Shu Shi, Jie Fu, Xiuxiang Teng
Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine · 2002 · vol. 8(1) , pp. 11–15 · doi:10.1007/bf02934610 · PMID:11789280 · W1210039319
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⚙ AI-generated summary by claude@2026-06+body, 2026-06-12 ⓘ

Combined laparoscopy and Chinese herbal medicine therapy showed higher cyst shrinking and disappearance rates, and a better pregnancy rate with fewer side effects than other treatments for endometrial ovarian cysts.

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⚙ AI-generated deep summary by claude@2026-06, 2026-06-07 · read from full text ⓘ

This randomized clinical study enrolled 152 patients with endometrial ovarian cyst and compared three treatments: combined laparoscopy plus Chinese herbal medicine, Chinese herbal medicine alone, and danazol, assessing clinical efficacy, side effects, and changes in CA125, reproductive endocrine hormones, and prostaglandins. The combination group showed significantly higher cyst shrinking, disappearance, and markedly effective rates than the other two groups, and it also had a higher pregnancy rate than the danazol group, with few side effects noted as an advantage for the combination and CHM groups. After treatment, prostaglandin F1α decreased, progesterone increased, and CA125 decreased across groups, with statistical significance reported for these changes. This paper is centrally about endometriosis — it investigates combined laparoscopy and Chinese herbal medicine for endometrial ovarian cyst, a form of endometriosis involving ovarian lesions.

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Abstract

ObjectiveTo investigate a new method of integrated laparoscopy with Chinese herbal medicine (CHM) in treating endometrial ovarian cyst.MethodsOne hundred and fifty-two patients with endometrial ovarian cyst were randomly treated with three therapies: Integrated laparoscopy with CHM (combination group), CHM (TCM group) and Danazol (WM group). To compare the clinical efficacy and side-effects of the three groups and to elucidate the therapeutic mechanism by detecting the serum CA125 reproductive endocrine hormone, plasma PGF1 alpha, PGE2 etc.ResultsThe shrinking rate and disappearance rate of the cysts, and markedly effective rate of combination group were obviously higher than those of TCM group and WM group (P < 0.05, P < 0.01). The pregnancy rate of combination group was also higher than that of WM group (P < 0.05). Few side-effects were the most prominent advantage for combination group and TCM group. After treatment, the plasma PGF1 alpha lowered remarkably, serum p.o. increased and CA125 reduced obviously (P < 0.01, P < 0.05).ConclusionThe integrated laparoscopy and CHM combination therapy is a new method in treating endometrial ovarian cyst with significant efficacy, minimal adverse effect and maximal preservation of reproductive function.
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Abstract

Objective: To investigate a new method of combined laparoscopy with Chinese herbal medicine (CHM) in treating endometrial ovarian cyst.

Methods

One hundred and fifty-two patients with endometrial ovarian cyst were randomly divided into 3 groups treated with three therapies: combined laparoscopy with CHM (combination group), CHM (TCM group) and danazol (WM group). To compare the clinical efficacy and sideeffects shown by the three groups and to elucidate the therapeutic mechanism by detecting the serum CA125 reproductive endocrine hormone, plasma prostaglandin F2a prostaglandin E2 etc.

Results

The shrinking rate, disappearance rate of the cysts and markedly effective rate in the combination group were obviously higher than those in the TCM group and WM group (P< 0.05,P<0.01). The pregnancy rate of combination group was also higher than that of the WM group (P<0.05). Few side-effects constituted the most prominent advantage for the combination group and TCM group. After treatment, the plasma prostaglandin F1a lowered remarkably, serum progesterone increased and CA125 reduced obviously (P<0.01,P<0.05).

Conclusion

The laparoscopy and CHM combination therapy is a new method in treating endometrial ovarian cyst which has significant efficacy, minimal adverse effect and maximal preservation of reproductive function. Similar content being viewed by others

References

Obs/Gyn Specialty Committee of Chinese Association of Integration of Traditional and Western Medicine. Criteria of diagnosis and treatment by combination of TCM and WM for endometriosis, pregnancy induced hypertension and female infertility. Chin J Integr Trad West Med 1991; 11 (6): 376–379. Zalel Y. Transvaginal sonographic measurements of post menopausal ovarian volume as a possible detection of ovarian neoplasia. Acta Obstet Gynecol Scand 1996;75:668–671. Sugimura K. MRI in predicting the response of ovarian endometriomas to hormone therapy. J Comput Assist Tomogr 1996; 20:145–150. Faycz JA. Comparison of different treatment methods of endometriomas by laparoscopy. Obstet Gynecol 1991; 78: 660–665. Author information Authors and Affiliations Corresponding author Rights and permissions About this article Cite this article Wu, YN., Hua, L., Jin, Y. et al. Clinical study on endometrial ovarian cyst treated by combined laparoscopy and chinese herbal medicine. CJIM 8, 11–15 (2002). https://doi.org/10.1007/BF02934610 Received: Issue date: DOI: https://doi.org/10.1007/BF02934610

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Condition tags

endometriosis

MeSH descriptors

Drugs, Chinese Herbal Endometriosis Laparoscopy Ovarian Cysts Adult Combined Modality Therapy Drugs, Chinese Herbal Endometriosis Female Humans Middle Aged Ovarian Cysts Ovarian Cysts

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SciLite annotations

chemicals 1
danazol

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