Effect of Shaohong Xiaojie Particle on the Expression of MMP-2 mRNA in Rats with Endometriosis
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Shaohong Xiaojie particle treatment of endometriosis in rats reduced ectopic endometriotic tissue volume and weight while decreasing MMP-2 mRNA expression.
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Abstract
OBJECTIVE To explore the mechanism of action of Shaohong Xiaojie particle in the treatment of endometriosis by investigating the expressions of MMP-2 mRNA in ectopic endometriums of rats with endometriosis.METHODS The expression of MMP-2 mRNA was tested by RT-PCR.RESULTS The tow dose-group could restrain the volume of ectopic endometriotic tissue(P0.05),and also can reduce its weight(P0.01).The expressions of MMP-2 mRNA was decreased simultaneously(P0.01).CONCLUSION Shaohong Xiaojie particle can decrease the expressions of MMP-2 mRNA in ectopic endometriums,which may be responsible for its therapeutie effect on endometriosis.
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- last seen: 2026-06-10T17:14:06.276822+00:00
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