Implementation of Dienogest as a Treatment for Infertility in Women with Endometriosis

Fertility problems affect between 4 and 5 million couples each year in Mexico alone, according to data recorded by the National Institute of Statistics and Geography (INEGI). Endometriosis is a benign disorder characterized by the presence of endometrial tissue outside the uterine cavity, which are estrogen-dependent and have resistance to progesterone. The main clinical manifestations are pelvic pain, infertility and the presence of an adnexal mass. The use of transvaginal ultrasound is able to detect endometriomas >20 mm. The gold standard is diagnostic laparoscopy. One of the drugs that has begun to be used in the management of infertility in patients who are candidates for in vitro fertilization is Dienogest, which is a fourth generation progesterone agonist. Dienogest has been shown to be effective in most cases and shows potential for treating and resolving infertility associated with endometriosis and added symptoms.