Application of treatment of laparoscopy combined with Zoladex to prevent endometriosis and nursing

Jing Wang, Yan Xu
In: Zhonghua xiandai huli zazhi · 2012 · vol. 18(31) , pp. 3788–3790 · doi:10.3760/cma.j.issn.1674-2907.2012.31.021 · W3030760336
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In 174 patients with stage III-IV endometriosis, six months of postoperative Nored therapy significantly reduced recurrence rates and increased pregnancy rates compared to no drug treatment.

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This study evaluated the efficacy of postoperative Zoladex therapy in preventing recurrence among 174 patients with stage III or IV endometriosis who underwent laparoscopic surgery. Participants were divided into an experimental group receiving six months of Zoladex treatment and a control group receiving no pharmacological intervention, with outcomes assessed over a two-year follow-up period. The results demonstrated that the Zoladex group experienced a significantly lower recurrence rate of 23.17 percent compared to 51.09 percent in the control group, alongside a substantially higher pregnancy rate of 80.00 percent versus 46.67 percent. This paper is centrally about endometriosis — specifically the use of GnRH agonists to prevent disease recurrence and improve fertility outcomes after surgical intervention.

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Abstract

Objective To study the effect of Zoladex therapy after endometriosis.Methods Totals of 174 cases with Ⅲ-Ⅳ endometriosis after laparoscopic surgery were randomly divided into experimental group (n =82),which received Nored therapy after endometriosis surgery and lasting 6 months,and control group (n =92)without any drug treatment.All patients were monthly followed up by telephone for two years,and postoperative recurrence rate and pregnancy rate in patients with infertility were observed and compared.Results After two years,the recurrence rate of experimental group was 23.17％,and that of control group was 51.09％,and the difference was statistically significant (P ＜ 0.05).The pregnancy rate of experimental group was 80.00％ significantly higher than 46.67％ of control group (x2 =6.419,P ＜ 0.05).Conclusions The endometriosis treated with Nored therapy is important for the patients which can effectively reduce the relapse rate,increase the rate of pregnancy,so as to the careful and effective nursing care to patient outcomes. Key words: Endometriosis; Laparoscopy; Recurrence; nursing; Nored
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腹腔镜手术联合诺雷德治疗在预防子宫内膜异位症复发中的应用及护理 Application of treatment of laparoscopy combined with Zoladex to prevent endometriosis and nursing 摘要目的 探讨子宫内膜异位症术后应用诺雷德对预防术后复发的效果及护理措施.方法 将174例Ⅲ～Ⅳ期子宫内膜异位症腹腔镜术后患者分为实验组82例及对照组92例,实验组于术后给予诺雷德治疗6个月,对照组未用任何药物治疗,随访2年后,比较两组患者术后复发情况及妊娠率.结果 术后2年实验组复发率为23.17％,低于对照组的51.09％,差异有统计学意义(x2=14.351,P＜0.05)；术后2年实验组患者妊娠率为80.00％,高于对照组的46.67％,差异有统计学意义(x2=6.419,P＜0.05).结论 子宫内膜异位症术后辅以诺雷德治疗能有效降低复发率,提高妊娠率,细心有效的护理对患者的治疗效果也至关重要. 更多相关知识 abstractsObjective To study the effect of Zoladex therapy after endometriosis.Methods Totals of 174 cases with Ⅲ-Ⅳ endometriosis after laparoscopic surgery were randomly divided into experimental group (n =82),which received Nored therapy after endometriosis surgery and lasting 6 months,and control group (n =92)without any drug treatment.All patients were monthly followed up by telephone for two years,and postoperative recurrence rate and pregnancy rate in patients with infertility were observed and compared.Results After two years,the recurrence rate of experimental group was 23.17％,and that of control group was 51.09％,and the difference was statistically significant (P ＜ 0.05).The pregnancy rate of experimental group was 80.00％ significantly higher than 46.67％ of control group (x2 =6.419,P ＜ 0.05).Conclusions The endometriosis treated with Nored therapy is important for the patients which can effectively reduce the relapse rate,increase the rate of pregnancy,so as to the careful and effective nursing care to patient outcomes. More相关知识 - 浏览416 - 被引12 - 下载53 相似文献 - 中文期刊 - 外文期刊 - 学位论文 - 会议论文

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