Association of MMP-9, ADMA, and sCD40L with ischemic stroke and correlations with stroke severity: A case-control study

Background: In the present study, we aimed to examine the correlation of serum levels of MMP-9, ADMA, and sCD40L with the occurrence and severity of acute ischemic stroke. Methods All routines analyses were performed using a Cobas platform. MMP-9, ADMA, and sCD40L were measured using ELISA kit. Results Compared with the controls, the stroke group showed higher MMP-9,higher sCD40L and higher ADMA. There were significant positive correlations between the NIHSS scores and MMP-9, sCD40L and ADMA. Conclusions Our study indicated that serum levels of MMP-9, sCD40L, and ADMA are associated with ischemic stroke and are correlated with the NIHSS scores at admission.