Low-Dose-Rate Brachytherapy for Treatment of
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This paper describes uterus didelphys, a congenital variant where the uterus is paired with two horns and cervices, occurring in 0.1-0.5% of women, and discusses hysterectomy as the primary treatment with radiation therapy having a controversial adjuvant role.
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Abstract
Uterus didelphys identifies the condition in which the uterus is present as apairedorgan,with two separateuterinehorns andcervices facing their ipsilateral fallopian tube and ovary. This normal congen-ital human anatomic variant occurs when the embryonic mullerian ducts do not fuse to form a single organ.Women with this condition are often unaware of having a double uterus and may be asymptom-atic. An estimated 0.1 % to 0.5 % of women in the United States have this condition.1 Primary carcinoma of the uterus accounts for an estimated 43,470newlydiagnosedcancers inwomen in theUnitedStates, andan estimated 7,950 women are projected to die of endometrial cancer– related disease.2 Hysterectomy with bilateral salpingo-oophorectomy with optional lymphadenectomyhas been the primary treatmentmo-dality, with radiation therapy having an established, albeit controver-sial, adjuvant role inearly- andadvanced-stagedisease.3-7 althoughthe
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- last seen: 2026-05-14T06:13:00.653308+00:00
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