Endometriosis and adenomyosis in the crosshair: variants of one disorder or fortuitous coincidence
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Recent findings on shared pathophysiology and endometrial receptivity, particularly in assisted reproduction, suggest endometriosis and adenomyosis may be variants of a single disorder rather than distinct entities.
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Abstract
Adenomyosis and endometriosis share a common origin as both of them result from the development of endometrial tissue outside the endometrium. Despite this, the 2 disorders were until recently considered as 2 different entities notably, because of their different epidemiology. Today, however, new findings regarding core similarities in pathophysiology and endometrial receptivity - not altered in assisted reproductive technology when using frozen embryo transfers - tend to reunite these 2 ailments as variants of 1 disorder.
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- europepmc
- last seen: 2026-08-17T06:11:01.428247+00:00
- pubmed
- last seen: 2026-08-17T06:10:35.235480+00:00
- unpaywall
- last seen: 2026-05-14T19:30:52.867331+00:00
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Courtesy of the U.S. National Library of Medicine
Courtesy of the U.S. National Library of Medicine