Clinicopathological Study of Tubal Ectopic Gestation in a Tertiary Care Centre

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Abstract

Background: Implantation of fertilized ovum at an aberrant site outside the uterus is termed as ectopic gestation. More than 95% of ectopic gestation occurs in fallopian tube and has a multifactorial pathogenesis with numerous contributing risk factors. This study was undertaken to assess the clinical presentation and predisposing risk factors of tubal ectopic gestation. Methods: This was a retrospective study conducted in a tertiary care centre, for a period of three years, from October 2017 to September 2020, in the department of pathology. All cases of tubal ectopic gestation confirmed by histopathology were included in the study. Demographic data, clinical presentation and data regarding the predisposing risk factors of tubal ectopic gestation were collected from the medical records. Results: The study includes a total of 88 cases that are confirmed by histopathological analysis. Majority of the cases were in the age group of 26 to 30 years. Pain abdomen was the most common clinical presentation followed by bleeding per vagina. The highest incidence of tubal ectopic gestation is among nulliparous women followed by women with para 1 and para 2 status. Pelvic inflammatory disease, previous history of caesarean section followed by previous history of other pelvic surgeries, abortion, bilateral tubal ligation (recanalized), and infertility treatment are the most common risk factors. Conclusion: Identification of risk factors helps the clinician to conduct a precise workup which aids in early diagnosis of tubal ectopic gestation. Thus, a timely intervention can reduce the morbidity and mortality associated with tubal ectopic gestation.
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Background

Implantation of fertilized ovum at an aberrant site outside the uterus is termed as ectopic gestation. More than 95% of ectopic gestation occurs in fallopian tube and has a multifactorial pathogenesis with numerous contributing risk factors. This study was undertaken to assess the clinical presentation and predisposing risk factors of tubal ectopic gestation. Methods: This was a retrospective study conducted in a tertiary care centre, for a period of three years, from October 2017 to September 2020, in the department of pathology. All cases of tubal ectopic gestation confirmed by histopathology were included in the study. Demographic data, clinical presentation and data regarding the predisposing risk factors of tubal ectopic gestation were collected from the medical records. Results: The study includes a total of 88 cases that are confirmed by histopathological analysis. Majority of the cases were in the age group of 26 to 30 years. Pain abdomen was the most common clinical presentation followed by bleeding per vagina. The highest incidence of tubal ectopic gestation is among nulliparous women followed by women with para 1 and para 2 status. Pelvic inflammatory disease, previous history of caesarean section followed by previous history of other pelvic surgeries, abortion, bilateral tubal ligation (recanalized), and infertility treatment are the most common risk factors. Conclusion: Identification of risk factors helps the clinician to conduct a precise workup which aids in early diagnosis of tubal ectopic gestation. Thus, a timely intervention can reduce the morbidity and mortality associated with tubal ectopic gestation.

Abstract

(English)

Background

Implantation of fertilized ovum at an aberrant site outside the uterus is termed as ectopic gestation. More than 95% of ectopic gestation occurs in fallopian tube and has a multifactorial pathogenesis with numerous contributing risk factors. This study was undertaken to assess the clinical presentation and predisposing risk factors of tubal ectopic gestation. Methods: This was a retrospective study conducted in a tertiary care centre, for a period of three years, from October 2017 to September 2020, in the department of pathology. All cases of tubal ectopic gestation confirmed by histopathology were included in the study. Demographic data, clinical presentation and data regarding the predisposing risk factors of tubal ectopic gestation were collected from the medical records. Results: The study includes a total of 88 cases that are confirmed by histopathological analysis. Majority of the cases were in the age group of 26 to 30 years. Pain abdomen was the most common clinical presentation followed by bleeding per vagina. The highest incidence of tubal ectopic gestation is among nulliparous women followed by women with para 1 and para 2 status. Pelvic inflammatory disease, previous history of caesarean section followed by previous history of other pelvic surgeries, abortion, bilateral tubal ligation (recanalized), and infertility treatment are the most common risk factors. Conclusion: Identification of risk factors helps the clinician to conduct a precise workup which aids in early diagnosis of tubal ectopic gestation. Thus, a timely intervention can reduce the morbidity and mortality associated with tubal ectopic gestation. Files IJTPR,Vol12,Issue10,Article7.pdf Files (335.7 kB) | Name | Size | Download all | |---|---|---| | md5:a2ae8a67b9cf70992c2e97d663546611 | 335.7 kB | Preview Download | Additional details Dates - Accepted - 2022-10-10 Software

References

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