Analysis of the relationship between lifestyle and postoperative cardiac and cerebrovascular complications after major abdominal surgery: a cohort study

Analysis of the relationship between lifestyle and postoperative cardiac and cerebrovascular complications after major abdominal surgery: a cohort study | Research Square window.SnipcartSettings = { analytics: { enabled: false } }; (function() { var accessVector = localStorage.getItem('access_vector') || ''; window.dataLayer = window.dataLayer || []; if (accessVector) { window.dataLayer.push({ user: { profile: { profileInfo: { snid: accessVector } } } }); } })(); (function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start':new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0],j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src='https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f);})(window,document,'script','dataLayer','GTM-K279D39R'); Browse Preprints In Review Journals COVID-19 Preprints AJE Video Bytes Research Tools Research Promotion AJE Professional Editing AJE Rubriq About Preprint Platform In Review Editorial Policies Our Team Advisory Board Help Center Sign In Submit a Preprint Cite Share Download PDF Article Analysis of the relationship between lifestyle and postoperative cardiac and cerebrovascular complications after major abdominal surgery: a cohort study Hye-Won Oh, Hae-Young Kim, Jae Hee Woo, Su-Yeon Hwang, Eun-Hye Koh, and 3 more This is a preprint; it has not been peer reviewed by a journal. https://doi.org/ 10.21203/rs.3.rs-6822635/v1 This work is licensed under a CC BY 4.0 License Status: Under Review Version 1 posted 7 You are reading this latest preprint version Abstract Background: This study investigated the association between lifestyle-related factors and the risk of cardiac and cerebrovascular disease in patients who underwent major abdominal surgery, using the Korean National Health Insurance Service (NHIS) data. Methods: We analyzed individuals aged >40 years who received health check-ups between 2009 and 2018. Among these data, we enrolled 108,261 patients who underwent major abdominal surgery and were followed-up to assess the development of cardiac or cerebrovascular disease for 1 year after surgery. Logistic regression was used to evaluate the association between lifestyle-related factors — body mass index, metabolic syndrome, alcohol consumption, cigarette smoking, and physical activity —and the outcomes. Results: Patients with metabolic syndrome and current smokers had a significantly higher risk of developing both cardiac and cerebrovascular disease within 1 year after major abdominal surgery. Ex-smokers and overweight patients had a higher risk of postoperative cerebrovascular disease. Alcohol consumption was associated with a reduced risk of cardiac disease and high levels of physical activity were linked to a reduced risk of cerebrovascular events. Conclusion: Our data suggest that lifestyle modification including weight control and cessation of smoking before undergoing major abdominal surgery may prevent postoperative cardiac and cerebrovascular risks. Health sciences/Medical research Health sciences/Risk factors abdominal surgery lifestyle cardiac disease cerebrovascular disease cohort study Full Text Additional Declarations No competing interests reported. Supplementary Files SupplementaryTables.doc Cite Share Download PDF Status: Under Review Version 1 posted Reviews received at journal 24 Sep, 2025 Reviewers agreed at journal 17 Sep, 2025 Reviewers invited by journal 15 Sep, 2025 Editor assigned by journal 09 Sep, 2025 Editor invited by journal 17 Jun, 2025 Submission checks completed at journal 17 Jun, 2025 First submitted to journal 04 Jun, 2025 You are reading this latest preprint version Research Square lets you share your work early, gain feedback from the community, and start making changes to your manuscript prior to peer review in a journal. As a division of Research Square Company, we’re committed to making research communication faster, fairer, and more useful. We do this by developing innovative software and high quality services for the global research community. Our growing team is made up of researchers and industry professionals working together to solve the most critical problems facing scientific publishing. Also discoverable on Platform About Our Team In Review Editorial Policies Advisory Board Help Center Resources Author Services Accessibility API Access RSS feed Manage Cookie Preferences © Research Square 2026 | ISSN 2693-5015 (online) Privacy Policy Terms of Service Do Not Sell My Personal Information {"props":{"pageProps":{"initialData":{"identity":"rs-6822635","acceptedTermsAndConditions":true,"allowDirectSubmit":false,"archivedVersions":[],"articleType":"Article","associatedPublications":[],"authors":[{"id":516776395,"identity":"ca735774-4ba2-41af-8c22-7e4ba9400ec4","order_by":0,"name":"Hye-Won Oh","email":"","orcid":"","institution":"Ewha Womans University","correspondingAuthor":false,"prefix":"","firstName":"Hye-Won","middleName":"","lastName":"Oh","suffix":""},{"id":516776396,"identity":"220472d5-2c88-4c41-9504-27f0d6701a82","order_by":1,"name":"Hae-Young Kim","email":"","orcid":"","institution":"Korea 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study","fulltext":[],"fulltextSource":"","fullText":"","funders":[],"hasAdminPriorityOnWorkflow":false,"hasManuscriptDocX":false,"hasOptedInToPreprint":true,"hasPassedJournalQc":"","hasAnyPriority":false,"hideJournal":false,"highlight":"","institution":"","isAcceptedByJournal":false,"isAuthorSuppliedPdf":true,"isDeskRejected":"","isHiddenFromSearch":false,"isInQc":false,"isInWorkflow":false,"isPdf":true,"isPdfUpToDate":true,"isWithdrawnOrRetracted":false,"journal":{"display":true,"email":"[email protected]","identity":"scientific-reports","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":false,"externalIdentity":"scirep","sideBox":"Learn more about [Scientific Reports](http://www.nature.com/srep/)","snPcode":"","submissionUrl":"","title":"Scientific Reports","twitterHandle":"","acdcEnabled":true,"dfaEnabled":true,"editorialSystem":"stoa","reportingPortfolio":"Scientific Reports","inReviewEnabled":true,"inReviewRevisionsEnabled":true},"keywords":"abdominal surgery, lifestyle, cardiac disease, cerebrovascular disease, cohort study","lastPublishedDoi":"10.21203/rs.3.rs-6822635/v1","lastPublishedDoiUrl":"https://doi.org/10.21203/rs.3.rs-6822635/v1","license":{"name":"CC BY 4.0","url":"https://creativecommons.org/licenses/by/4.0/"},"manuscriptAbstract":"\u003cp\u003e\u003cstrong\u003eBackground:\u003c/strong\u003eThis study investigated the association between lifestyle-related factors and the risk of cardiac and cerebrovascular disease in patients who underwent major abdominal surgery, using the Korean National Health Insurance Service (NHIS) data.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eMethods:\u003c/strong\u003e We analyzed individuals aged \u0026gt;40 years who received health check-ups between 2009 and 2018. Among these data, we enrolled 108,261 patients who underwent major abdominal surgery and were followed-up to assess the development of cardiac or cerebrovascular disease for 1 year after surgery. Logistic regression was used to evaluate the association between lifestyle-related factors — body mass index, metabolic syndrome, alcohol consumption, cigarette smoking, and physical activity —and the outcomes.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eResults:\u003c/strong\u003e Patients with metabolic syndrome and current smokers had a significantly higher risk of developing both cardiac and cerebrovascular disease within 1 year after major abdominal surgery. Ex-smokers and overweight patients had a higher risk of postoperative cerebrovascular disease. Alcohol consumption was associated with a reduced risk of cardiac disease and high levels of physical activity were linked to a reduced risk of cerebrovascular events.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eConclusion:\u003c/strong\u003eOur data suggest that lifestyle modification including weight control and cessation of smoking before undergoing major abdominal surgery may prevent postoperative cardiac and cerebrovascular risks.\u003c/p\u003e","manuscriptTitle":"Analysis of the relationship between lifestyle and postoperative cardiac and cerebrovascular complications after major abdominal surgery: a cohort study","msid":"","msnumber":"","nonDraftVersions":[{"code":1,"date":"2025-09-23 12:35:00","doi":"10.21203/rs.3.rs-6822635/v1","editorialEvents":[{"type":"communityComments","content":0},{"type":"editorInvitedReview","content":"","date":"2025-09-24T04:31:59+00:00","index":"hide","fulltext":""},{"type":"reviewerAgreed","content":"282836953720927430483623535866493338913","date":"2025-09-18T01:03:29+00:00","index":"hide","fulltext":""},{"type":"reviewersInvited","content":"","date":"2025-09-15T17:49:59+00:00","index":"","fulltext":""},{"type":"editorAssigned","content":"","date":"2025-09-09T10:41:04+00:00","index":"","fulltext":""},{"type":"editorInvited","content":"","date":"2025-06-17T10:09:51+00:00","index":"","fulltext":""},{"type":"checksComplete","content":"","date":"2025-06-17T10:08:46+00:00","index":"","fulltext":""},{"type":"submitted","content":"Scientific Reports","date":"2025-06-04T16:53:33+00:00","index":"","fulltext":""}],"status":"published","journal":{"display":true,"email":"[email protected]","identity":"scientific-reports","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":false,"externalIdentity":"scirep","sideBox":"Learn more about [Scientific Reports](http://www.nature.com/srep/)","snPcode":"","submissionUrl":"","title":"Scientific Reports","twitterHandle":"","acdcEnabled":true,"dfaEnabled":true,"editorialSystem":"stoa","reportingPortfolio":"Scientific Reports","inReviewEnabled":true,"inReviewRevisionsEnabled":true}}],"origin":"","ownerIdentity":"99636492-99d1-4ad0-b13e-449a8c91445e","owner":[],"postedDate":"September 23rd, 2025","published":true,"recentEditorialEvents":[],"rejectedJournal":[],"revision":"","amendment":"","status":"under-review","subjectAreas":[{"id":54907918,"name":"Health sciences/Medical research"},{"id":54907919,"name":"Health sciences/Risk factors"}],"tags":[],"updatedAt":"2025-09-23T12:35:01+00:00","versionOfRecord":[],"versionCreatedAt":"2025-09-23 12:35:00","video":"","vorDoi":"","vorDoiUrl":"","workflowStages":[]},"version":"v1","identity":"rs-6822635","journalConfig":"researchsquare"},"__N_SSP":true},"page":"/article/[identity]/[[...version]]","query":{"redirect":"/article/rs-6822635","identity":"rs-6822635","version":["v1"]},"buildId":"XKTyCvWXoU3ODBz1xrDgd","isFallback":false,"isExperimentalCompile":false,"dynamicIds":[84888],"gssp":true,"scriptLoader":[]}