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Abstract

cysts do not impair follicles development, oocyte and embryo quality: report on eight controlled ovarian hyperstimulations and ICSI cycles Sir, We thank Benaglia et al. (2009) for their interesting study. In contrast to Nakagawa et al. (2008), they found that spontaneous ovulation is impaired in ovaries affected by endometriotic cysts. The same group previously observed hypo-responsiveness of the affected ovaries to gonadotrophin-induced controlled ovarian hyperstimulation (COH) (Somigliana et al., 2006a, b). In all studies, ovulation was only pre-sumed by ultrasound (US) criteria. We report herein on three infertile patients with unilateral ovarian endometriotic cysts diagnosed according to current US criteria (Mais et al., 1993) and undergoing three minimally stimulated (one patient) and five COH ICSI cycles (two patients). All health information regarding the patients have been rendered anonymous and they con-sented to this publication. Institutional Review Board approval has been obtained for this clinical study. This study is in accordance with the Helsinki Declaration of 1975 regarding human experimentation. Patient #1: L.P. aged 37, secondary infertility, was diagnosed with one 16 mm endometriotic cyst on her right ovary. She was offered a minimally stimulated ICSI cycle using rFSH (Gonal F, Merck

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