Effects of PKF 115–584 on cell migration and invasion.

A, B: Number of migrated cells/mm2 in non-treated and PKF 115–584–treated epithelial (A) and stromal (B) cells of endometriotic tissue and matched eutopic endometrium of the same patient. C, D: Representative photomicrographs of migration of non-treated and PKF 115–584–treated epithelial (C) and stromal (D) cells of endometriotic tissue and matched eutopic endometrium of a same patient (magnification x100). E, F: Number of invasive cells/mm2 in non-treated and PKF 115–584–treated epithelial (E) and stromal (F) cells of endometriotic tissue and matched eutopic endometrium of the same patients. G, H: Representative photomicrographs of invasion of non-treated and PKF 115–584–treated epithelial (G) and stromal (H) cells of endometriotic tissue and matched eutopic endometrium of a same patient (magnification x100). Results are presented as the mean+SEM. Epithelial cells of endometriotic tissue and matched eutopic endometrium of the same patients (n = 16). Stromal cells of endometriotic tissue and matched eutopic endometrium (n = 16). a: p<.05 versus matched eutopic endometrium of the same patients.