Successful ICU Management of Generalized Tetanus Arising from Minor Trauma Without Booster Immunization in a Third Category Hospital in Cameroon

Successful ICU Management of Generalized Tetanus Arising from Minor Trauma Without Booster Immunization in a Third Category Hospital in Cameroon | Authorea try { document.documentElement.classList.add('js'); } catch (e) { } var _gaq = _gaq || []; _gaq.push(['_setAccount', 'G-8VDV14Y67G']); _gaq.push(['_trackPageview']); (function() { var ga = document.createElement('script'); ga.type = 'text/javascript'; ga.async = true; ga.src = ('https:' == document.location.protocol ? 'https://ssl' : 'http://www') + '.google-analytics.com/ga.js'; var s = document.getElementsByTagName('script')[0]; s.parentNode.insertBefore(ga, s); })(); Skip to main content Preprints Collections Wiley Open Research IET Open Research Ecological Society of Japan All Collections About About Authorea FAQs Contact Us Quick Search anywhere Search for preprint articles, keywords, etc. Search Search ADVANCED SEARCH SCROLL This is a preprint and has not been peer reviewed. Data may be preliminary. 30 January 2026 V1 Latest version Share on Successful ICU Management of Generalized Tetanus Arising from Minor Trauma Without Booster Immunization in a Third Category Hospital in Cameroon Authors : Philippe-Albert Lingo 0009-0009-9446-5311 [email protected] , Christian Fotso , Horline Bougoue Takou , Christian Damien Tchuisseu Ngapjang , Alix Leclerc Mtack Ngouanom , Quincy Jones Tchumukong Shumbang , Marc Effila A. , Bertolt Kouam Nteungue , Ronald Gobina , and Vincent Verla S. Authors Info & Affiliations https://doi.org/10.22541/au.176980820.02572764/v1 85 views 133 downloads Contents Abstract Supplementary Material Information & Authors Metrics & Citations View Options References Figures Tables Media Share Abstract Although the incidence of tetanus has dramatically declined due to widespread vaccination, it remains a significant public health concern in underdeveloped regions. We report the case of a 20-year-old man, single, university student, incompletely immunized, who presented with generalized tetanic spasms following a neglected wound on the left hallux. He was referred to Limbe Regional Hospital for advanced management. On examination, the patient exhibited dysautonomia with blood pressure of 170/98 mmHg, temperature of 40 °C, pulse rate of 140 bpm, trismus, generalized clonic spasms, and a necrotic wound on the dorsal aspect of the left hallux. A diagnosis of generalized tetanus was established. Additional investigations included full blood count, blood culture, renal function tests, malaria parasite screening, and lumbar puncture. Management in the intensive care unit focused on controlling spasms and autonomic dysfunction, neutralizing the toxin, eradicating the causative organism, and initiating tetanus vaccination. The patient's clinical course was favorable, with recovery achieved without adverse events. This case underscores the persistent problem of inadequate immunization against tetanus among young adults in our setting and highlights the critical role of intensive care in the management of severe tetanus. Supplementary Material File (case report tetanus(4).pdf) Download 293.94 KB Information & Authors Information Version history V1 Version 1 30 January 2026 Copyright This work is licensed under a Non Exclusive No Reuse License. Keywords cameroon immunization intensive care unit tetanus Authors Affiliations Philippe-Albert Lingo 0009-0009-9446-5311 [email protected] View all articles by this author Christian Fotso Critical Care Unit -Limbe Regional Hospital View all articles by this author Horline Bougoue Takou Surgical Unit -Limbe Regional Hospital View all articles by this author Christian Damien Tchuisseu Ngapjang Department of Internal Medicine and Pediatrics-Faculty of Health Sciences, University of Buea View all articles by this author Alix Leclerc Mtack Ngouanom Department of Epidemiology, Université Catholique d'Afrique Centrale View all articles by this author Quincy Jones Tchumukong Shumbang Department of Internal Medicine and Pediatrics-Faculty of Health Sciences, University of Buea View all articles by this author Marc Effila A. View all articles by this author Bertolt Kouam Nteungue View all articles by this author Ronald Gobina Department of Internal Medicine and Pediatrics-Faculty of Health Sciences, University of Buea View all articles by this author Vincent Verla S. Department of Internal Medicine and Pediatrics-Faculty of Health Sciences, University of Buea View all articles by this author Metrics & Citations Metrics Article Usage 85 views 133 downloads .FvxKWukQNSOunydq8rnd { width: 100px; } Citations Download citation Philippe-Albert Lingo, Christian Fotso, Horline Bougoue Takou, et al. Successful ICU Management of Generalized Tetanus Arising from Minor Trauma Without Booster Immunization in a Third Category Hospital in Cameroon. Authorea . 30 January 2026. DOI: https://doi.org/10.22541/au.176980820.02572764/v1 If you have the appropriate software installed, you can download article citation data to the citation manager of your choice. Simply select your manager software from the list below and click Download. For more information or tips please see 'Downloading to a citation manager' in the Help menu . Format Please select one from the list RIS (ProCite, Reference Manager) EndNote BibTex Medlars RefWorks Direct import Tips for downloading citations document.getElementById('citMgrHelpLink').addEventListener('click', function() { popupHelp(this.href); return false; }); $(".js__slcInclude").on("change", function(e){ if ($(this).val() == 'refworks') $('#direct').prop("checked", false); $('#direct').prop("disabled", ($(this).val() == 'refworks')); }); View Options View options PDF View PDF Figures Tables Media Share Share Share article link Copy Link Copied! Copying failed. Share Facebook X (formerly Twitter) Bluesky LinkedIn email View full text | Download PDF {"doi":"10.22541/au.176980820.02572764/v1","type":"Article"} Now Reading: Share Figures Tables Close figure viewer Back to article Figure title goes here Change zoom level Go to figure location within the article Download figure Toggle share panel Toggle share panel Share Toggle information panel Toggle information panel Go to previous graphic Go to next graphic Go to previous table Go to next table All figures All tables View all material View all material xrefBack.goTo xrefBack.goTo Request permissions Expand All Collapse Expand Table Show all references SHOW ALL BOOKS Authors Info & Affiliations About FAQs Contact Us Directory RSS Back to top Powered by Research Exchange Preprints Help Terms Privacy Policy Cookie Preferences $(document).ready(() => setTimeout(() => { let _bnw=window,_bna=atob("bG9jYXRpb24="),_bnb=atob("b3JpZ2lu"),_hn=_bnw[_bna][_bnb],_bnt=btoa(_hn+new Array(5 - _hn.length % 4).join(" ")); $.get("/resource/lodash?t="+_bnt); },4000)); (function(){function c(){var b=a.contentDocument||a.contentWindow.document;if(b){var d=b.createElement('script');d.innerHTML="window.__CF$cv$params={r:'9fe251a498fc3fe2',t:'MTc3OTE4NTUwMA=='};var a=document.createElement('script');a.src='/cdn-cgi/challenge-platform/scripts/jsd/main.js';document.getElementsByTagName('head')[0].appendChild(a);";b.getElementsByTagName('head')[0].appendChild(d)}}if(document.body){var a=document.createElement('iframe');a.height=1;a.width=1;a.style.position='absolute';a.style.top=0;a.style.left=0;a.style.border='none';a.style.visibility='hidden';document.body.appendChild(a);if('loading'!==document.readyState)c();else if(window.addEventListener)document.addEventListener('DOMContentLoaded',c);else{var e=document.onreadystatechange||function(){};document.onreadystatechange=function(b){e(b);'loading'!==document.readyState&&(document.onreadystatechange=e,c())}}}})();