Cerebrovascular Accident in Patent Foramen Ovale: A Unique Case Report of a New Therapeutic Method – Biotronics

Cerebrovascular Accident in Patent Foramen Ovale: A Unique Case Report of a New Therapeutic Method – Biotronics | Research Square window.SnipcartSettings = { analytics: { enabled: false } }; (function() { var accessVector = localStorage.getItem('access_vector') || ''; window.dataLayer = window.dataLayer || []; if (accessVector) { window.dataLayer.push({ user: { profile: { profileInfo: { snid: accessVector } } } }); } })(); (function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start':new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0],j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src='https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f);})(window,document,'script','dataLayer','GTM-K279D39R'); Browse Preprints In Review Journals COVID-19 Preprints AJE Video Bytes Research Tools Research Promotion AJE Professional Editing AJE Rubriq About Preprint Platform In Review Editorial Policies Our Team Advisory Board Help Center Sign In Submit a Preprint Cite Share Download PDF Case Report Cerebrovascular Accident in Patent Foramen Ovale: A Unique Case Report of a New Therapeutic Method – Biotronics Tomáš Pfeiffer, Marcela Slavíková This is a preprint; it has not been peer reviewed by a journal. https://doi.org/ 10.21203/rs.3.rs-6997959/v1 This work is licensed under a CC BY 4.0 License Status: Posted Version 1 posted You are reading this latest preprint version Abstract Introduction. Patent foramen ovale (PFO) receives considerable attention in cardiovascular medicine, usually requiring surgery. In this report, we would like to present a highly unique therapeutic outcome after use of a new discipline of complementary medicine – the Josef Zezulka Biotronics. Case presentation. A 31-year-old man was hospitalized with a cerebrovascular accident (CVA) of embolic origin due to paradoxical embolism in PFO. Right-sided hemiplegia developed as a consequence of this embolism. Anticoagulant therapy and rehabilitation were initiated. Health condition slightly improved. Seven months after the CVA, the patient underwent two cycles of biotronic treatment, i.e. a non-invasive method of spiritual energy therapy, resulting in significant improvement in his health condition. Subsequently, he went through seven more cycles of the biotronic treatment, resulting in further improvement of not only the neurological disability but also the cardiac defect. The transoesophageal echocardiography (TEE) did not show the initially identified atrial septal defect. Due to the uniqueness of the result, the TEE was repeated eleven days later – with the same conclusion. Foramen ovale was entirely closed. Thus, the patient’s anticoagulant therapy was discontinued and switched to antiplatelet therapy. The CVA has not recurred. Conclusions. The foramen ovale closure without a surgical intervention, which initially seemed necessary, is a remarkably unique therapeutic outcome, indicating potential significant benefit of biotronic treatment in integrative healthcare. This new discipline and its possible therapeutic potential, not only in cardiovascular diseases, should therefore be subjected to more detailed research. Cardiac & Cardiovascular Systems Integrative & Complementary Medicine cerebrovascular accident patent foramen ovale biotronics paradoxical embolism hemiplegia stroke Full Text Additional Declarations The authors declare no competing interests. Cite Share Download PDF Status: Posted Version 1 posted You are reading this latest preprint version Research Square lets you share your work early, gain feedback from the community, and start making changes to your manuscript prior to peer review in a journal. As a division of Research Square Company, we’re committed to making research communication faster, fairer, and more useful. We do this by developing innovative software and high quality services for the global research community. Our growing team is made up of researchers and industry professionals working together to solve the most critical problems facing scientific publishing. Also discoverable on Platform About Our Team In Review Editorial Policies Advisory Board Help Center Resources Author Services Accessibility API Access RSS feed Manage Cookie Preferences © Research Square 2026 | ISSN 2693-5015 (online) Privacy Policy Terms of Service Do Not Sell My Personal Information {"props":{"pageProps":{"initialData":{"identity":"rs-6997959","acceptedTermsAndConditions":true,"allowDirectSubmit":true,"archivedVersions":[],"articleType":"Case Report","associatedPublications":[],"authors":[{"id":477741465,"identity":"921e128d-27a5-4b60-9a80-73b06f57f397","order_by":0,"name":"Tomáš Pfeiffer","email":"data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAZAAAAAyAQMAAABI0h/eAAAABlBMVEX///8AAABVwtN+AAAACXBIWXMAAA7EAAAOxAGVKw4bAAABD0lEQVRIie2QMUvDQBTH33FgloOsrxTMV0hmS++rJAh2aQc3J0nI4KDSNeKXiAQ6dXhwoIvVNdIOBSGuyRbBwUsrLvWso8P9lrt7vB/v3h/AYvnHuMDZugYY7G8VX2cv5jzIAE66B4v/psBGUfsV6VxGTQsrdB3O4mb+LN3b9G3dzMHzDKIQi6IvoMJeylmSVcsoW90H+gJBYlJwkvf1f8595T68ClqGUIZBKghCbtoFJ8V7Cwql4iz9oCfplaNmoxyYlRkKrfhcK0DE8nK8nSJMyuNidiT8ClFPSa7oOLorx6c3GWGX3484F9fFS3umE5sqFrc0lIflKK9rGhgT2+LTTgl/6+/YVSwWi8XyzSdxvVxiSOCDNwAAAABJRU5ErkJggg==","orcid":"https://orcid.org/0000-0003-0398-6437","institution":"Professional Chamber Sanator - the Union of Biotronicists of Josef Zezulka","correspondingAuthor":true,"prefix":"","firstName":"Tomáš","middleName":"","lastName":"Pfeiffer","suffix":""},{"id":477741466,"identity":"a1d4369d-d5f8-45d5-b713-ac1ea47cee57","order_by":1,"name":"Marcela Slavíková","email":"","orcid":"https://orcid.org/0000-0001-9485-5154","institution":"Second Department of Cardiovascular Surgery, General University Hospital and First Faculty of Medicine, Charles University","correspondingAuthor":false,"prefix":"","firstName":"Marcela","middleName":"","lastName":"Slavíková","suffix":""}],"badges":[],"createdAt":"2025-06-28 13:06:39","currentVersionCode":1,"declarations":{"humanSubjects":true,"vertebrateSubjects":false,"conflictsOfInterestStatement":false,"humanSubjectEthicalGuidelines":true,"humanSubjectConsent":true,"humanSubjectClinicalTrial":false,"humanSubjectCaseReport":true,"vertebrateSubjectEthicalGuidelines":false},"doi":"10.21203/rs.3.rs-6997959/v1","doiUrl":"https://doi.org/10.21203/rs.3.rs-6997959/v1","draftVersion":[],"editorialEvents":[],"editorialNote":"","failedWorkflow":false,"files":[{"id":85815023,"identity":"6e4e511f-42e8-4d25-bb7f-7afefb725732","added_by":"auto","created_at":"2025-07-02 05:06:30","extension":"pdf","order_by":1,"title":"","display":"","copyAsset":false,"role":"manuscript-pdf","size":303440,"visible":true,"origin":"","legend":"","description":"","filename":"Pfeiffer2025.pdf","url":"https://assets-eu.researchsquare.com/files/rs-6997959/v1_covered_a722ddf0-cbd7-425d-9cbe-54ab0e143a33.pdf"}],"financialInterests":"The authors declare no competing interests.","formattedTitle":"\u003cp\u003eCerebrovascular Accident in Patent Foramen Ovale: A Unique Case Report of a New Therapeutic Method – Biotronics\u003c/p\u003e","fulltext":[],"fulltextSource":"","fullText":"","funders":[],"hasAdminPriorityOnWorkflow":false,"hasManuscriptDocX":false,"hasOptedInToPreprint":true,"hasPassedJournalQc":"","hasAnyPriority":true,"hideJournal":true,"highlight":"","institution":"Professional Chamber Sanator - the Union of Biotronicists of Josef Zezulka","isAcceptedByJournal":false,"isAuthorSuppliedPdf":true,"isDeskRejected":"","isHiddenFromSearch":false,"isInQc":false,"isInWorkflow":false,"isPdf":true,"isPdfUpToDate":true,"isWithdrawnOrRetracted":false,"journal":{"display":true,"email":"[email protected]","identity":"researchsquare","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":true,"externalIdentity":"","sideBox":"","snPcode":"","submissionUrl":"/submission","title":"Research Square","twitterHandle":"researchsquare","acdcEnabled":true,"dfaEnabled":false,"editorialSystem":"","reportingPortfolio":"","inReviewEnabled":false,"inReviewRevisionsEnabled":true},"keywords":"cerebrovascular accident, patent foramen ovale, biotronics, paradoxical embolism, hemiplegia, stroke","lastPublishedDoi":"10.21203/rs.3.rs-6997959/v1","lastPublishedDoiUrl":"https://doi.org/10.21203/rs.3.rs-6997959/v1","license":{"name":"CC BY 4.0","url":"https://creativecommons.org/licenses/by/4.0/"},"manuscriptAbstract":"\u003cp\u003e\u003cstrong\u003eIntroduction. \u003c/strong\u003ePatent foramen ovale (PFO) receives considerable attention in cardiovascular medicine, usually requiring surgery. In this report, we would like to present a highly unique therapeutic outcome after use of a new discipline of complementary medicine – the Josef Zezulka Biotronics.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eCase presentation. \u003c/strong\u003eA 31-year-old man was hospitalized with a cerebrovascular accident (CVA) of embolic origin due to paradoxical embolism in PFO. Right-sided hemiplegia developed as a consequence of this embolism. Anticoagulant therapy and rehabilitation were initiated. Health condition slightly improved. Seven months after the CVA, the patient underwent two cycles of biotronic treatment, i.e. a non-invasive method of spiritual energy therapy, resulting in significant improvement in his health condition. Subsequently, he went through seven more cycles of the biotronic treatment, resulting in further improvement of not only the neurological disability but also the cardiac defect. 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