[The effect of follicular fluid from patients with endometriosis, follicle stimulating hormone and bone morphogenetic protein 15 on the proliferation and progesterone secretion of granular cells].

Xinni Wang, Xin Wang, X F Wang, X N Lin, Xiuying Lin, Youjin Dai, Y D Dai, X Lin, Xiao-Min Lin, H M Lü, F Zhou, Fu-zhen Zhou, S Y Zhang
Zhonghua yi xue za zhi · 2017 · vol. 97(45) , pp. 3543–3547 · doi:10.3760/cma.j.issn.0376-2491.2017.45.006 · PMID:29275592 · W3024502660
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Abstract

FSH, but not BMP-15, was able to enhance the proliferation and progesterone secretion of granular cells. The proliferation of granular cells and secretion of progesterone were inhibited by the follicular fluid from patients with endometriosis, which was reversed by FSH. However, BMP-15 had no effect on the outcome of follicular fluid from patients with endometriosis.

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Condition tags

endometriosis

MeSH descriptors

Bone Morphogenetic Protein 15 Cell Proliferation Endometriosis Follicle Stimulating Hormone Follicular Fluid Granulosa Cells Bone Morphogenetic Protein 15 Estradiol Female Follicle Stimulating Hormone Follicular Fluid Granulosa Cells Humans Male Progesterone

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SciLite annotations

chemicals 5
progesterone progesterone progesterone progesterone progesterone
organisms 1
human

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