Infertility attributed to endometriosis

Infertility is one of the significant, worrisome consequences of endometriosis which imposes physical, psychological, and social problems on women. According to cited statistical information, the rate of prevalence of infertility, as a symptom, in woman with endometriosis ranges from 30% to 50%. Comparing natural conception rates between infertile women with mild endometriosis and those with unexplained infertility, the former group experiences a significantly lower conception rate over 3 years than the latter group. Taken together, all these observations give an inference that endometriosis reduces fertility that may roughly correlate with extent of the disease. Nevertheless, certain cross-sectional studies have shown that age, superficial peritoneal endometriosis, and previous surgery for endometriosis have significantly higher associations with infertility related to endometriosis compared with isolated endometrioma. Although there is a well-documented association reported in the literature, the substantial cause–effect relationship is highly debatable and remains controversial till now.