Оценка частоты использования заместительной гормональной терапии у женщин с преждевременной недостаточностью яичников по обращаемости

This article presents an assessment  of the frequency of use of HRT in 29 women with premature ovarian failure (POF) seeking medical advice in the clinic of the Scientific Centre for Family Health and Human Reproduction Problems from April 2014 till December 2016. The mean age was 34±4,65 years. All patients signed the informed consent and were added to the international POI registry (https//:poiregistry.net). The most frequent complaints were depression (83%), hot flashes (76%), anxiety (69%), menstrual disorders (65%); primary infertility was detected in 52%. Serum hormone levels (M±SD) were as follows: FSH –53±27,4 IU/mL, AMH – 0,16±0,13 ng/mL. The most frequent POI causes were pelvic surgery (58%), including ones due to endometriosis (17%), and genetic causes (10%). At the time of the treatment, only 11 women were diagnosed with POF. Only 5 out of 29 patients (17%) received hormonal treatment for POF: three of them used hormone replacement therapy, and two received combined oral contraceptives. Moreover, two women underwent total surgical sterilization were not prescribed HRT in due course.