Application of high intensity focused ultrasound combined with Mirena in treatment of chronic pelvic pain

Objective:To explore the clinical efficacy and safety of high intensity focused ultrasound combined with Mirena in treatment of chronic pelvic pain. Methods:Thirty-eight patients were treated with surgery and high intensity focused ultrasound combined with Mirena because they were not responsive to pharmacotherapy,19 patients in each group;the scores of visual analogue scale(VAS) and plasma substance P levels before treatment and at 7 days,one month,and two months after treatment,the degrees of satisfaction at three and six months after treatment were evaluated and analyzed retrospectively. Results:The scores of VAS and plasma substance P levels at one month and two months after treatment in the two groups were significantly lower than those before treatment(P0.05).Pain was relieved obviously or disappeared after treatment.The scores of VAS and plasma substance P levels at one month and two months after treatment in surgery group were lower than those in combined treatment group.At three and six months after treatment,the degrees of satisfaction in surgery group showed decreasing trends,there was significant difference(P0.05).The degrees of satisfaction in combined treatment group maintained at a stable level,and which were superior to those in surgery group. Conclusion:The clinical efficacy of high intensity focused ultrasound combined with Mirena is good,which is a safe and effective method.