Perforating Gout: Expanding the Differential for Transepidermal Elimination

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Abstract

Perforating dermatoses are dermatologic disorders with transepidermal elimination (TE) of dermal substances. While TE is typically associated with collagen and elastin, it can also occur as a secondary event in other processes, and it is important to keep a broad differential. We present a case of perforating tophaceous gout, which underscores the need for a thoughtful approach to perforating disorders. An updated review of recent literature is also presented.

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europepmc
last seen: 2026-05-19T01:45:01.086888+00:00