Preparation and coating of finely dispersed drugs

Srečo D. Škapin; Egon Matijević

doi:10.1016/j.jcis.2003.08.035

Preparation and coating of finely dispersed drugs

Srečo D. Škapin, Egon Matijević

In: Journal of Colloid and Interface Science · 2003 · vol. 272(1) , pp. 90–98 · doi:10.1016/j.jcis.2003.08.035 · PMID:14985026 · W46803622

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This paper describes the preparation and coating of finely dispersed drugs.

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Abstract

The preparation of colloidal particles of different morphologies, including spheres, of two drugs, loratadine and danazol, is described. In principle these particles were obtained by precipitation when nonsolvents (water or aqueous surfactant solutions) were added to ethanol solutions of the drug. In addition, procedures were developed that made it possible to use the drug particles thus obtained as cores to be then coated with either silica or aluminum (hydrous) oxide layers. The presence of these inorganic shells was confirmed by electron microscopy, energy dispersive spectroscopy, and electrophoresis.

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Cites (1)

Particle size reduction for improvement of oral bioavailability of hydrophobic drugs: I. Absolute oral bioavailability of nanocrystalline danazol in beagle dogs 1995

References (16)

Particle size reduction for improvement of oral bioavailability of hydrophobic drugs: I. Absolute oral bioavailability of nanocrystalline danazol in beagle dogs via openalex
doi:10.1006/jcis.2001.8137 via openalex
doi:10.1557/jmr.1994.0436 via openalex
doi:10.1006/jcis.1998.5730 via openalex
doi:10.1021/cen-v081n008.p032 via openalex
doi:10.1016/0378-5173(95)00148-c via openalex
doi:10.1006/jcis.2000.7012 via openalex
doi:10.1021/la00013a003 via openalex
doi:10.1006/jcis.1999.6106 via openalex
doi:10.1007/bf02111396 via openalex
doi:10.1021/j100725a052 via openalex
doi:10.1016/0095-8522(64)90035-2 via openalex
doi:10.1016/0021-9797(92)90229-f via openalex
doi:10.1006/jcis.2002.8408 via openalex
doi:10.1201/9781482294668 via openalex
doi:10.1557/jmr.1996.0396 via openalex

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[1] Particle size reduction for improvement of oral bioavailability of hydrophobic drugs: I. Absolute oral bioavailability of nanocrystalline danazol in beagle dogs 1995