A Landmark-based Common Coordinate Framework for Spatial Transcriptomics Data

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Abstract

1 The increasing amount of spatial transcriptomics data prompts for means to amalgamate observations from distinct experiments, especially attractive is to cast quantities from different sources into a common coordinate frame-work (CCF) to relate signals across space. We here present a method that enables transfer of information from multiple samples to a reference representing a CCF, and show its utility by analyzing an assortment of real and synthetic data sets.

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europepmc
last seen: 2026-05-19T01:45:01.086888+00:00