[Scanning electron microscopic method for studying the interaction of normal peritoneal macrophages with tumor cells].

In: Eksperimental'naia onkologiia · 1986 · vol. 8(6) , pp. 52–7 · PMID:3100268 · W2994298308
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Abstract

It is shown that the damage action of normal peritoneal macrophages of mice includes inhibition of the proliferating activity of the mastocytoma P-815 cells and their complete destruction accompanied by the breaks of their cytoplasmic membrane. Scanning electron microscopy was used to reveal two types of contacts between peritoneal macrophages and cells P-815; the loss of microvilli and the appearance of blebs on cell surface in the case of adsorption of P-815 cells on macrophages; the contact through long filopodia which are sent forth by macrophages in the case when contacting cells are at some distance from each other.

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