GENITAL ENDOMETRIOSIS ASSOCIATED WITH INFERTILITY

The problem of infertility has an important socio- medical signifi cance, which is due to a sharp decline infertility in the context of current crisis. Despite many years of research, endometriosis remains a disease with uncertain etiology. Its prevalence is constantly increasing and accounts for 15-50% of the entire population of women of reproductive age. The high social signifi cance of the problem of endometriosis is determined by the fact that 30-40% of women with endometriosis suff er from infertility. A retrospective analysis of 485 case histories of female patients who applied to Yuzko Medical Center for infertility in the period 2019-2022 was conducted. The main group (I) consisted of 435 women with infertility associated with endometriosis. Control (II) consisted of 50 women with tubal- peritoneal factor infertility. The obtained results are processed by the method of variation statistics. It was found that in women with infertility associated with endometriosis, pain was observed in 305 patients (70.2%).The dependence of the pain syndrome on menstruation was noted (60.2% of cases). Primary infertility was found in 40.3% of patients of group I and 84.6% of group II, secondary infertility was diagnosed in 38% of group I and 21% of patients of group II which is 73.6% (main group) and 10 women (21.3%) of the control group. Type I – 114 (26.4%) women of the main group and 42 women (84.6%) of the control group. In the case of the studied patients (group I), an increase in CA 125 was detected in only 25.8% of cases among all studied for this parameter.