The Effect of Etiological Factors on the Pregnancy Rate of in Vitro Fertilization and Embryo Transfer (IVF-ET)

Objective To study the effect of etiological factors on pregnancy rate of in vitro fertilization and embryo transfer. Methods Data of 234 cycles of IVF-ET, which were performed in the Guangdong Jiai Genetics IVF Institute from January to December in 2004, were analyzed retrospectively. Patients were divided into five groups according to the female factors. Group A: 86 cycles with both tubal obstruction or after tubal sterilization; group B: 79 cycles with one or two side tubal salpingitis; group C: 24 cycles with one or two side hydrosalpinx; group D: 24 cycles with endometriosis; group E: 21 cycles with artificial insemination by husband (AIH) failure for more than three times. Fertilization rate, cleavage rate, implantation rate and clinical pregnancy rate, miscarriage rate, ectopic pregnancy rate of the five groups were compared. Results There is no difference in fertilization rate, cleavage rate and implantation rate between five groups. The clinical pregnancy rate of group A is higher than that of group C and group D (P0.05). The miscarriage rate of group E is higher than group A and group B, while group D is higher than group B (P0.05). The ectopic pregnancy rate of group A is lower than group C (P0.05). Conclusion To improve the IVF-ET result, we may treat the couples according to the sterility factors before IVF-ET.