Diffuse Uterine Leiomyomatosis: A Case Report and Review of the Literature

Background: Diffuse uterine leiomyomatosis is a benign disease with a low incidence rate, mainly manifested as menorrhagia and infertility. Due to its clinical manifestations similar to multiple uterine myomas or adenomyosis, it is often misdiagnosed in clinical practice. Research has found that they can be distinguished through histopathological examination. According to existing reported cases, Diffuse uterine leiomyomatosis mainly occurs during the child-bearing period and has a significant impact on fertility. Hysterectomy is recognized as a radical cure, but uterine-sparing treatment methods need to be continuously explored. Case: A 41-year-old woman presented with recurrent menorrhagia 5 years after myomectomy. B-ultrasound examination indicated that the uterus was enlarged and the myometrium was full of hypoechoic, Considering the patient's desire to preserve the uterus, we performed laparotomy myomectomy again. Result: Hysteroscopic myomectomy has been shown to have a certain therapeutic effect on infertile patients in the early stage of DUL. Laparotomy myomectomy can remove a wider range of lesions and can be combined with gonadotropin releasing hormone agonists or antagonists for pretreatment. Uterine artery embolization is also a commonly administered therapy. High-intensity focused ultrasound ablation has been used with significant success in reducing uterine volume but requires further evaluation for its impact on fertility. Conclusion: A DUL patient underwent extensive myomectomy. This atudy further discussed uterine-sparing treatments, and reviewed existing research reports. | Published in | Journal of Gynecology and Obstetrics (Volume 11, Issue 2) | | DOI | 10.11648/j.jgo.20231102.15 | | Page(s) | 52-55 | | Creative Commons | This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. | | Copyright | Copyright © The Author(s), 2023. Published by Science Publishing Group |

Diffuse Uterine Leiomyomatosis, Laparotomy Myomectomy, Uterine-Sparing Treatments

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(2023). Diffuse Uterine Leiomyomatosis: A Case Report and Review of the Literature. Journal of Gynecology and Obstetrics, 11(2), 52-55. https://doi.org/10.11648/j.jgo.20231102.15 ACS Style Wenpeng Xue; Bin Tang; Yang Li; Hong Zheng; Ya He, et al. Diffuse Uterine Leiomyomatosis: A Case Report and Review of the Literature. J. Gynecol. Obstet. 2023, 11(2), 52-55. doi: 10.11648/j.jgo.20231102.15 AMA Style Wenpeng Xue, Bin Tang, Yang Li, Hong Zheng, Ya He, et al. Diffuse Uterine Leiomyomatosis: A Case Report and Review of the Literature. J Gynecol Obstet. 2023;11(2):52-55. doi: 10.11648/j.jgo.20231102.15 - @article{10.11648/j.jgo.20231102.15, author = {Wenpeng Xue and Bin Tang and Yang Li and Hong Zheng and Ya He and Weiwei Wei and Ruxia Shi and Jiming Chen}, title = {Diffuse Uterine Leiomyomatosis: A Case Report and Review of the Literature}, journal = {Journal of Gynecology and Obstetrics}, volume = {11}, number = {2}, pages = {52-55}, doi = {10.11648/j.jgo.20231102.15}, url = {https://doi.org/10.11648/j.jgo.20231102.15}, eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.jgo.20231102.15}, abstract = {Background: Diffuse uterine leiomyomatosis is a benign disease with a low incidence rate, mainly manifested as menorrhagia and infertility. Due to its clinical manifestations similar to multiple uterine myomas or adenomyosis, it is often misdiagnosed in clinical practice. Research has found that they can be distinguished through histopathological examination. According to existing reported cases, Diffuse uterine leiomyomatosis mainly occurs during the child-bearing period and has a significant impact on fertility. Hysterectomy is recognized as a radical cure, but uterine-sparing treatment methods need to be continuously explored. Case: A 41-year-old woman presented with recurrent menorrhagia 5 years after myomectomy. B-ultrasound examination indicated that the uterus was enlarged and the myometrium was full of hypoechoic, Considering the patient's desire to preserve the uterus, we performed laparotomy myomectomy again. Result: Hysteroscopic myomectomy has been shown to have a certain therapeutic effect on infertile patients in the early stage of DUL. Laparotomy myomectomy can remove a wider range of lesions and can be combined with gonadotropin releasing hormone agonists or antagonists for pretreatment. Uterine artery embolization is also a commonly administered therapy. High-intensity focused ultrasound ablation has been used with significant success in reducing uterine volume but requires further evaluation for its impact on fertility. Conclusion: A DUL patient underwent extensive myomectomy. This atudy further discussed uterine-sparing treatments, and reviewed existing research reports.}, year = {2023} } - TY - JOUR T1 - Diffuse Uterine Leiomyomatosis: A Case Report and Review of the Literature AU - Wenpeng Xue AU - Bin Tang AU - Yang Li AU - Hong Zheng AU - Ya He AU - Weiwei Wei AU - Ruxia Shi AU - Jiming Chen Y1 - 2023/04/27 PY - 2023 N1 - https://doi.org/10.11648/j.jgo.20231102.15 DO - 10.11648/j.jgo.20231102.15 T2 - Journal of Gynecology and Obstetrics JF - Journal of Gynecology and Obstetrics JO - Journal of Gynecology and Obstetrics SP - 52 EP - 55 PB - Science Publishing Group SN - 2376-7820 UR - https://doi.org/10.11648/j.jgo.20231102.15 AB - Background: Diffuse uterine leiomyomatosis is a benign disease with a low incidence rate, mainly manifested as menorrhagia and infertility. Due to its clinical manifestations similar to multiple uterine myomas or adenomyosis, it is often misdiagnosed in clinical practice. Research has found that they can be distinguished through histopathological examination. According to existing reported cases, Diffuse uterine leiomyomatosis mainly occurs during the child-bearing period and has a significant impact on fertility. Hysterectomy is recognized as a radical cure, but uterine-sparing treatment methods need to be continuously explored. Case: A 41-year-old woman presented with recurrent menorrhagia 5 years after myomectomy. B-ultrasound examination indicated that the uterus was enlarged and the myometrium was full of hypoechoic, Considering the patient's desire to preserve the uterus, we performed laparotomy myomectomy again. Result: Hysteroscopic myomectomy has been shown to have a certain therapeutic effect on infertile patients in the early stage of DUL. Laparotomy myomectomy can remove a wider range of lesions and can be combined with gonadotropin releasing hormone agonists or antagonists for pretreatment. Uterine artery embolization is also a commonly administered therapy. High-intensity focused ultrasound ablation has been used with significant success in reducing uterine volume but requires further evaluation for its impact on fertility. Conclusion: A DUL patient underwent extensive myomectomy. This atudy further discussed uterine-sparing treatments, and reviewed existing research reports. VL - 11 IS - 2 ER - Author Information Copyright © 2012 -- 2026 Science Publishing Group – All rights reserved.