Design of a liposome with the property to induce CD16 on cervical cancer cells with a purified spermidine-cholesterol

Abstract Purpose Use of a purified cationic lipid for fabricate liposomes capable of inducing the appearance of CD16 receptors on the membranes of cervical carcinoma cells.Methods Chemical synthesis of purified spermidine-cholesterol; liposome fabrication; UPLC-MS analysis; Cell culture; Flow cytometry.Results The construction of a liposomal system with a highly purified spermidine-cholesterol with CD16 inducing capacity on cervical cancer cells.Conclusion We were able to synthetize a highly purified spermidine-cholesterol to fabricate a liposomal system capable to induce CD16 on cervical cancer cells.