Auto-Immune Haemolytic Anaemia in Ulcerative Colitis
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This paper reports two cases of autoimmune haemolytic anaemia complicating ulcerative colitis, contributing to a review that categorizes forty associated cases into those independent of and those dependent on active colitis.
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Abstract
We report 2 patients with auto-immune haemolytic anaemia (AIHA) complicating ulcerative colitis (UC), each with a hitherto undescribed feature. In the 1st case, direct antiglobulin test showed red cells coated with complement only, and the 2nd case was successfully treated with danazol. These 2 patients bring to 40 the number of cases of AIHA associated with UC. A review of the clinical details suggests that the patients may be divided into two distinct groups. In the first (4/40), AIHA seems to occur as an auto-immune event independent of the activity of UC; in the second group (36/40), AIHA is apparently dependent on active colitis, i.e. control of colitis is crucial to control haemolysis.
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- openalex
- last seen: 2026-05-11T05:37:28.352103+00:00
- unpaywall
- last seen: 2026-10-02T06:31:42.897446+00:00
License: CC0
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