IUI Outcomes in Patients with Endometriosis in Half Year after Laparoscopic Treatment

Objective: To investigate the clinical outcomes of intrauterine insemination(IUI) in infertility women with endometriosis in half year after laparoscopic treatment. Methods:Ninety-eight patients with endometriosis(stage Ⅰ-Ⅲ) treated by laparoscopy, from January 2010 to December 2012 at Zhongshan People′ s Hospital, were divided into three groups: nature cycle plus IUI(NC +IUI), controlled ovarian hyperstimulation plus IUI(COS+IUI), and expectant treatment without IUI(ET control), with the informed consent. The pregnancy rates of three groups in half year after operation were compared. Results:The pregnancy rate per cycle, and the cumulative pregnancy rate in half a year were 6.1%(12/197) and 28.6%(12/42) in the ET control group, 6.6%(4/61) and 10.5%(4/38) in the NC+IUI group, and 14.8%(4/27) and 22.2%(4/18) in the COS+IUI group. Interestingly, there were no significant differences in those rates among three groups(P0.05). Conclusions:There is not significant difference in the pregnancy rate in those infertility patients with endometriosis(stage I-III) in half year after the laparoscopic treatment combined with IUI and without IUI(expectant treatment). Of course, it is necessary to study further with more samples.