A case report: Exudative retinal detachment secondary to combined infection of H1N1 influenza and Mycoplasma 

A case report: Exudative retinal detachment secondary to combined infection of H1N1 influenza and Mycoplasma | Research Square window.SnipcartSettings = { analytics: { enabled: false } }; (function() { var accessVector = localStorage.getItem('access_vector') || ''; window.dataLayer = window.dataLayer || []; if (accessVector) { window.dataLayer.push({ user: { profile: { profileInfo: { snid: accessVector } } } }); } })(); (function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start':new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0],j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src='https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f);})(window,document,'script','dataLayer','GTM-K279D39R'); Browse Preprints In Review Journals COVID-19 Preprints AJE Video Bytes Research Tools Research Promotion AJE Professional Editing AJE Rubriq About Preprint Platform In Review Editorial Policies Our Team Advisory Board Help Center Sign In Submit a Preprint Cite Share Download PDF Short Report A case report: Exudative retinal detachment secondary to combined infection of H1N1 influenza and Mycoplasma Min Wu, Wenzhi Yang, Dan He, Zhuo Lang, Aoxue Yan, Geeta Menon, and 1 more This is a preprint; it has not been peer reviewed by a journal. https://doi.org/ 10.21203/rs.3.rs-8712006/v1 This work is licensed under a CC BY 4.0 License Status: Under Review Version 1 posted 11 You are reading this latest preprint version Abstract Background: H1N1 influenza and Mycoplasma are common causes of pneumonia, but ocular symptoms after infection are rare. We report a case of bilateral decreased vision, exudative retinal detachment and high intraocular pressure secondary to H1N1 influenza and mycoplasma infection. Case presentation: A 7-year-old male presented with decreased vision in his right eye and was found to have exudative retinal detachment and high intraocular pressure secondary to combined infection of H1N1 influenza and mycoplasma. The boy was previously diagnosed with X-linked congenital retinoschisis (XLRS) at age 3. After anti-viral and anti-mycoplasma treatments, the exudative retinal detachment resolved, and the intraocular pressure was under control. Conclusions: This case highlights the possibility of exudative retinal detachment secondary to H1N1 influenza and mycoplasma, especially in patients with short axial length. Exudative retinal detachment H1N1 influenza mycoplasma high intraocular pressure X-linked congenital retinoschisis Full Text Additional Declarations No competing interests reported. Cite Share Download PDF Status: Under Review Version 1 posted Editorial decision: Revision requested 23 Mar, 2026 Reviews received at journal 17 Mar, 2026 Reviewers agreed at journal 07 Mar, 2026 Reviewers agreed at journal 07 Mar, 2026 Reviewers agreed at journal 06 Mar, 2026 Reviews received at journal 12 Feb, 2026 Reviewers agreed at journal 12 Feb, 2026 Reviewers invited by journal 12 Feb, 2026 Editor assigned by journal 27 Jan, 2026 Submission checks completed at journal 27 Jan, 2026 First submitted to journal 27 Jan, 2026 You are reading this latest preprint version Research Square lets you share your work early, gain feedback from the community, and start making changes to your manuscript prior to peer review in a journal. As a division of Research Square Company, we’re committed to making research communication faster, fairer, and more useful. We do this by developing innovative software and high quality services for the global research community. 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Also discoverable on Platform About Our Team In Review Editorial Policies Advisory Board Help Center Resources Author Services Accessibility API Access RSS feed Manage Cookie Preferences © Research Square 2026 | ISSN 2693-5015 (online) Privacy Policy Terms of Service Do Not Sell My Personal Information {"props":{"pageProps":{"initialData":{"identity":"rs-8712006","acceptedTermsAndConditions":true,"allowDirectSubmit":false,"archivedVersions":[],"articleType":"Short Report","associatedPublications":[],"authors":[{"id":591723834,"identity":"a776d1cd-3456-41e2-8819-c246b889c839","order_by":0,"name":"Min 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Infection","twitterHandle":"@SpringerOpen","acdcEnabled":true,"dfaEnabled":true,"editorialSystem":"em","reportingPortfolio":"BMC/SO AJ","inReviewEnabled":true,"inReviewRevisionsEnabled":true},"keywords":"Exudative retinal detachment, H1N1 influenza, mycoplasma, high intraocular pressure, X-linked congenital retinoschisis","lastPublishedDoi":"10.21203/rs.3.rs-8712006/v1","lastPublishedDoiUrl":"https://doi.org/10.21203/rs.3.rs-8712006/v1","license":{"name":"CC BY 4.0","url":"https://creativecommons.org/licenses/by/4.0/"},"manuscriptAbstract":"\u003cp\u003eBackground: H1N1 influenza and Mycoplasma are common causes of pneumonia, but ocular symptoms after infection are rare. We report a case of bilateral decreased vision, exudative retinal detachment and high intraocular pressure secondary to H1N1 influenza and mycoplasma infection.\u003c/p\u003e\n\u003cp\u003eCase presentation: A 7-year-old male presented with decreased vision in his right eye and was found to have exudative retinal detachment and high intraocular pressure secondary to combined infection of H1N1 influenza and mycoplasma. The boy was previously diagnosed with X-linked congenital retinoschisis (XLRS) at age 3. After anti-viral and anti-mycoplasma treatments, the exudative retinal detachment resolved, and the intraocular pressure was under control.\u003c/p\u003e\n\u003cp\u003eConclusions: This case highlights the possibility of exudative retinal detachment secondary to H1N1 influenza and mycoplasma, especially in patients with short axial length.\u003c/p\u003e","manuscriptTitle":"A case report: Exudative retinal detachment secondary to combined infection of H1N1 influenza and Mycoplasma ","msid":"","msnumber":"","nonDraftVersions":[{"code":1,"date":"2026-02-17 15:16:29","doi":"10.21203/rs.3.rs-8712006/v1","editorialEvents":[{"type":"communityComments","content":0},{"type":"decision","content":"Revision requested","date":"2026-03-23T07:29:15+00:00","index":"","fulltext":""},{"type":"editorInvitedReview","content":"","date":"2026-03-17T07:09:01+00:00","index":"hide","fulltext":""},{"type":"reviewerAgreed","content":"27443357390186046262844128310337906980","date":"2026-03-07T08:59:27+00:00","index":"hide","fulltext":""},{"type":"reviewerAgreed","content":"41815166742873222099343129242072769482","date":"2026-03-07T07:23:04+00:00","index":"hide","fulltext":""},{"type":"reviewerAgreed","content":"262192673827751118014682568644428187386","date":"2026-03-06T10:04:16+00:00","index":"hide","fulltext":""},{"type":"editorInvitedReview","content":"","date":"2026-02-12T12:09:56+00:00","index":"hide","fulltext":""},{"type":"reviewerAgreed","content":"106561516292186177302087384417726280624","date":"2026-02-12T12:01:56+00:00","index":"hide","fulltext":""},{"type":"reviewersInvited","content":"","date":"2026-02-12T07:18:12+00:00","index":"","fulltext":""},{"type":"editorAssigned","content":"","date":"2026-01-27T22:48:37+00:00","index":"","fulltext":""},{"type":"checksComplete","content":"","date":"2026-01-27T22:47:52+00:00","index":"","fulltext":""},{"type":"submitted","content":"Journal of Ophthalmic Inflammation and Infection","date":"2026-01-27T14:54:24+00:00","index":"","fulltext":""}],"status":"published","journal":{"display":true,"email":"[email protected]","identity":"journal-of-ophthalmic-inflammation-and-infection","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":false,"externalIdentity":"joii","sideBox":"Learn more about [Journal of Ophthalmic Inflammation and Infection](http://joii-journal.springeropen.com)","snPcode":"12348","submissionUrl":"https://submission.nature.com/new-submission/12348/3","title":"Journal of Ophthalmic Inflammation and Infection","twitterHandle":"@SpringerOpen","acdcEnabled":true,"dfaEnabled":true,"editorialSystem":"em","reportingPortfolio":"BMC/SO AJ","inReviewEnabled":true,"inReviewRevisionsEnabled":true}}],"origin":"","ownerIdentity":"b0bd120e-1af8-4f80-8dc9-5ef75178a424","owner":[],"postedDate":"February 17th, 2026","published":true,"recentEditorialEvents":[],"rejectedJournal":[],"revision":"","amendment":"","status":"under-review","subjectAreas":[],"tags":[],"updatedAt":"2026-05-13T06:27:37+00:00","versionOfRecord":[],"versionCreatedAt":"2026-02-17 15:16:29","video":"","vorDoi":"","vorDoiUrl":"","workflowStages":[]},"version":"v1","identity":"rs-8712006","journalConfig":"researchsquare"},"__N_SSP":true},"page":"/article/[identity]/[[...version]]","query":{"redirect":"/article/rs-8712006","identity":"rs-8712006","version":["v1"]},"buildId":"XKTyCvWXoU3ODBz1xrDgd","isFallback":false,"isExperimentalCompile":false,"dynamicIds":[84888],"gssp":true,"scriptLoader":[]}