Comparison of Bond Strength of Different Indirect Composite Systems and CAD/CAM Composite Blocks between Dentin and Composite Surfaces: An in vitro study | Research Square window.SnipcartSettings = { analytics: { enabled: false } }; (function() { var accessVector = localStorage.getItem('access_vector') || ''; window.dataLayer = window.dataLayer || []; if (accessVector) { window.dataLayer.push({ user: { profile: { profileInfo: { snid: accessVector } } } }); } })(); (function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start':new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0],j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src='https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f);})(window,document,'script','dataLayer','GTM-K279D39R'); Browse Preprints In Review Journals COVID-19 Preprints AJE Video Bytes Research Tools Research Promotion AJE Professional Editing AJE Rubriq About Preprint Platform In Review Editorial Policies Our Team Advisory Board Help Center Sign In Submit a Preprint Cite Share Download PDF Article Comparison of Bond Strength of Different Indirect Composite Systems and CAD/CAM Composite Blocks between Dentin and Composite Surfaces: An in vitro study Oyun Erdene Batgerel, Oktay Yazıcıoğlu, Emine Kıtın, Burç İhsan Gençel, and 2 more This is a preprint; it has not been peer reviewed by a journal. https://doi.org/ 10.21203/rs.3.rs-3821900/v1 This work is licensed under a CC BY 4.0 License Status: Posted Version 1 posted You are reading this latest preprint version Abstract This study aims to compare the shear bond strength of different indirect restorative materials bonded to the microhybrid composite and dentin surfaces. A total of 192 cylindrical specimens (3mm height, 3mm diameter) were prepared from GradiaPlus, GC(GRA); CeramageBody, Shofu(CER); TesceraATL, Bisco(TES); and Lava Ultimate, 3M Espe(LAV) materials. In addition, 48 newly extracted molars were embedded in acrylic resin 2 mm below the cementoenamel junction and sliced horizontally using a cutting device (IsoMet 1000; Buehler, USA) to form flat dentin surfaces. Using a specially customized 4x2mm disc-shaped mold, 48 disc-shaped composite surfaces were obtained with the Z250 Microhybrid composite (3M Espe, USA) material by layering technique. A total of 2 cylindrical indirect composite specimens were cemented to each disc-shaped composite and flat dentin surfaces. Samples obtained from indirect composite were divided into 16 groups in total, with two different subgroups luted with RelyX U200(RX-U200) self-adhesive cement (3M Espe, USA) and RelyX Ultimate(RX-ULT) clicker dual-cure cement (3M Espe, USA) to the dentin and microhybrid composite surfaces (n = 12). Groups are respectively: 1)GRA + Dentin + RX-U200 2)TES + Dentin + RX-U200 3)CER + Dentin + RX-U200 4)LAVA + Dentin + RX-U200 5)GRA + Composite + RX-U200 6)TES + Composite + RX-U200 7)CER + Composite + RX-U200 8)LAVA + Composite + RX-U200 9)GRA + Dentin + RX-ULT 10)TES + Dentin + RX-ULT 11)CER + Dentin + RX-ULT 12)LAVA + Dentin + RX-ULT 13)GRA + Composite + RX-ULT 14)TES + Composite + RX-ULT 15)CER + Composite + RX-ULT 16)LAVA + Composite + RX-ULT (n = 12). The Shear Test was carried out by applying 0-400 N loading and 1 mm/min force to each sample at Instron Universal Testing Machine. Light microscopy and SEM were used to examine the failure type. The results obtained in the study were evaluated by using ShapiroWilk's test, Mann-Whitney U test and Chi-Square test.(p < 0.05) Significantly higher bonding values were obtained in the specimens bonded to the surface of Z250 microhybrid composite (3M ESPE, USA) compared to the specimens bonded to the dentin surface (p < 0.001). When the shear strength of indirect restoration materials is compared; the highest value was measured in the CER + Composite + RX-ULT(Av:91.41Mpa) group, and the lowest value was measured in the LAVA + Dentin + RX-U200(Mean:35.96Mpa) group(p < 0.001). When the bond strengths of the cement systems were compared, RX-ULT dual-cure cement showed higher bond strength values than RX-U200 self-adhesive cement on both dentin and Z250 Microhybrid composite surface (p < 0.05). Health sciences/Anatomy/Oral anatomy/Dentine Physical sciences/Materials science/Biomaterials Physical sciences/Engineering/Mechanical engineering Indirect composite micro-hybrid composite shear bond strength Figures Figure 1 Figure 2 Figure 3 Figure 4 Introduction As the trend towards minimally invasive approaches continues to gain traction, the progress in adhesive dentistry is progressively piquing interest. Employing minimally invasive techniques for tooth preparation serves the purpose of minimizing failures in both dental hard tissues and pulp tissue, thereby safeguarding the residual tooth structure and optimizing the natural functional capacities of the teeth to their utmost potential 1 . Numerous contemporary studies have consistently indicated that the conservation of intact tooth tissue significantly correlates with the longevity of dental restorations and overall tooth integrity 2 – 4 . Indirect restorations represent a therapeutic modality utilized for the restitution of the innate anatomical morphology, longevity, and esthetic qualities of teeth, particularly in addressing the loss of dental substrate attributable to caries or fractures in the posterior dentition. Posterior indirect restorations categorically encompass three delineations, namely inlay, onlay, and overlay, each predicated on the extent of the cavity's dimensions. Inlay restorations entail the rehabilitation of occlusal, proximal, and gingival cavities, yet without complete encasement of the occlusal surface. Onlay restorations, in contrast, entail the coverage of the occlusal surface as well as one or more cusps. Overlay restorations extend further, encapsulating the entire occlusal surface alongside tubercles, thereby enveloping the buccal and lingual facets of the clinical crown as well 5 , 6 . Inherent within the direct technique employing composite materials, the potential for complications such as polymerization shrinkage exists. Conversely, in the context of the indirect approach, the polymerization shrinkage associated with laboratory-based composite materials or ceramic restorations is confined to the utilization of the resin cement 7 Consequently, the drawbacks stemming from polymerization shrinkage within indirect restorations are effectively mitigated, thereby minimizing the prospect of suboptimal outcomes concerning interproximal contact points, occlusal morphological features, and marginal edge congruence 8 . Through an analysis of 11 scholarly investigations within the field, researchers have concluded that indirect restorative procedures yield superior preservation of both form and function when compared to direct restorations, particularly in cases involving significant loss of dental structure and tissue. These studies employed adhesion techniques utilizing dual-cure resin cements, offering a combination of mechanical interlocking and chemical bonding. When successful adhesion was achieved, it was observed that an exceptional level of fracture resistance was achieved through the intricate interplay between the irregular surface features within the cement and the restoration. These findings also underscored the attainment of outstanding bond strength and a notable deterrence against the propagation of potential fractures. 9 – 14 . Various methodologies exist for the fabrication of indirect restorations. The CAD/CAM (computer-aided design-computer-aided manufacturing) technique, which involves the utilization of optical reader cameras for processing scanned images in a computerized environment, was introduced by Bruce Altschuler of the United States in 1977. The incorporation of CAD/CAM technology into restorative dentistry can be traced back to the 1980s. In 1984, Francois Duret of France advanced the Duret system, named after himself, offering a more comprehensive single-member restoration approach. Subsequently, in 1988, Werner Mörmann and Marco Brandestini of Switzerland introduced the pioneering dental CAD/CAM application, enhancing parameters related to production, feasibility, and cost-effectiveness with the Cerec system 15 . The goal is to achieve enduring clinical success in dentistry through the continuous advancement of ceramic and composite blocks facilitated by CAD/CAM technology. Recent progress in materials science has ushered in a new era, yielding laboratory-fabricated indirect composite resins that are suitable for both indirect restorations and direct composite resins. These materials are crafted extracorally and subsequently polymerized within a controlled laboratory setting. Consequently, they offer the flexibility to employ various polymerization techniques such as high-energy ultraviolet light, heat, and pressure 16 , 17 . The enduring triumph of indirect composite resin restorations is intricately linked with the efficacious establishment of adhesion between the dental substrate and the restoration. Despite the multitude of adhesive choices available today, self-adhesive resin cements have been introduced to the clinical arena, aiming to curtail and mitigate potential procedural errors. While self-adhesive resin cements, designed for direct application devoid of a separate acid-etching and bonding step, offer a streamlined approach, debates persist surrounding their bond strength when contrasted with alternative etch-and-rinse and self-etch adhesive resin cements 18 , 19 . This in vitro investigation was undertaken to juxtapose the shear bond strength exhibited by distinct indirect composite materials, as affixed to both dentin and composite surfaces, utilizing varying adhesive resin cements. The formulated null hypotheses were as follows: 1. Comparable shear bond strength would be observed between traditional and CAD/CAM indirect composite materials. 2. Similar shear bond strength would be evident between dual-cure and self-cure adhesive cements. 3. The shear bond strength would exhibit parity on both dentin and composite surfaces. Methods Ethics information This study was approved by the Istanbul University Faculty of Dentistry Clinical Research Ethics Committee on February 19, 2020, with the approval number (No. 2020/6-REV2) and was supported by the Istanbul University Scientific Research Project (Project No: TDK-2020-36980) The shear bond strength test was carried out following the guidelines of ISO/TS 11405:2003. 20 Dentin Surface Preparation Forty-eight recently extracted human molar teeth, devoid of caries, restorations, fractures, and root canal interventions, underwent meticulous cleansing to eliminate both calculus and periodontal soft tissues. Subsequently, these teeth were immersed in a 0.1% thymol solution and stored under refrigeration at 4°C, for a duration not exceeding six months following extraction, spanning the duration of the assessment period. Teeth were embedded completely in autopolymerizing acrylic resin using a custom-made silicon mold and teeht were cut 2-3mm below the dentinoenamel junction using a round-ended tapered diamond bladed low-speed rotary microtome under water cooling. (Isomet 1000 Buehler Precision Saw, Düsseldorf, Germany). To establish a standardized and even dentin surface, the dentin facets of all utilized teeth were meticulously refined for a duration of 60 seconds with 600-grit silicon carbide papers (Buehler), while maintaining continuous water cooling(Buehler, Düsseldorf, Germany). Composite Surface Preparation A total of forty-eight composite surfaces, each measuring 4x2mm in a disc-shaped format, were fabricated using the Z250 Microhybrid composite (3M Espe, USA) material. A custom-designed metal mold was employed to create a negative impression, from which a silicone mold was generated. These composite discs were meticulously prepared using a horizontal layering technique and subsequently polymerized for 20 seconds with an LED light curing device (Demi Ultra LED Curing Light, Kerr). Preparation of Indirect Composite Specimens Lava™ Ultimate CAD/CAM Block(3M Espe, St.Paul,MN,ABD) Cylindrical samples with dimensions of 10x3 mm (10 mm in height, 3 mm in diameter) were created through the utilization of a CAD (Computer-Aided Design) software program. These prototypes were then translated into physical entities using a CAM (Computer-Aided Manufacturing) process, employing a Lava™ Ultimate (3M Espe, St.Paul,MN,ABD) nanoceramic-based resin composite block. Subsequently, the 10x3 mm cylindrical samples were sectioned into thirds, resulting in cylindrical samples measuring 3x3 mm, utilizing a low-speed rotary microtome under continuous water cooling. (Isomet 1000 Buehler Precision Saw, Düsseldorf, Germany). Gradia Plus(GC Corporation, Tokyo, Japan) A custom Teflon mold was designed to create cylindrical composite samples measuring 3x3mm. Subsequently, Gradia indirect composite was condensed into the Teflon mold using small pieces measuring 1mm with the assistance of cement fulvar. The condensed composite was pre-polymerized for 10 seconds using the GC steplight SL-1 device. Finally, the samples, which were polymerized using the layering method, were polymerized for a total of 3 minutes using the GC Labolight LV-III device. Tescera ATL(Bisco Inc., Schaumburg, IL, USA). A custom Teflon mold was designed to create cylindrical composite samples measuring 3x3mm. Subsequently, Tescera ATL indirect composite was condensed into the Teflon mold using small pieces measuring 1mm with the assistance of cement fulvar. The condensed composite was polymerized using an LED light device. The polymerization process was completed in a Tescera ATL light cup with pressure and light for 2 minutes. The final polymerization was carried out using the Tescera ATL Pressure/Light/Heat Cure Cup (Bisco Inc., Schaumburg, IL, USA) for 10–13 minutes with an oxygen scavenger capsule. All Tescera ATL samples were subjected to this process. Ceramage Body(Shofu Inc., Kyoto, Japan) A custom Teflon mold was designed to create cylindrical composite samples measuring 3x3mm. Subsequently, Ceramage Body (Shofu Inc., Kyoto, Japan) indirect composite was condensed into the Teflon mold using small pieces measuring 1mm with the assistance of cement fulvar. The condensed composite was pre-polymerized with the Sublite V device for 20 seconds. The samples, which were polymerized using the layering method, were polymerized for 5 minutes with the Solidilite V device. All Ceramage samples have been subjected to this process. Cementation procedure Ultradent Bonding Apparatus of UltraTester™ Bond Strength Testing Machine(Ultradent Products, Inc.) was used to standardize the cementation procedure. Acrylic blocks with dentin and Z250 microhybride composite disc surfaces were fixed to Ultradent Bonding Apparatus. Two indirect composite samples were then luted to each disc surface with a standart force (500 ± 50 gr) wighed with precision balance. For the eight Rely X-U200(3M ESPE, St. Paul, MN, USA) self-adhesive resin cement group; indirect composite samples were bonded to dentin and 3M Z250 microhybrid composite disc surfaces with direct cement application. Subsequently, polymerization was executed in strict adherence to the manufacturer's instructions, employing the Demi Ultra LED light device (Curing Light, Kerr). In the RelyX Ultimate adhesive resin cement group, Scotchbond Universal Etch(3M ESPE, St. Paul, MN, USA) acid was applied for 15sn to both dentin and 3M Z250 microhybrid composite disc surfaces. Then, Single Bond Universal(3M ESPE) adhesive system applied and polymerized with Demi Ultra LED light device (Curing Light, Kerr). Finally, RelyX Ultimate adhesive resin cement was applied according to the manufacturer's instructions and cured with the same light device. After cementation samples were stored in distilled water at 37°C for 24h. Study Groups The specimens were stratified into sixteen distinct groups based on the type of surface being cemented and the specific adhesive cement system employed. The configuration of these study groups is delineated in Table 1 , with comprehensive details pertaining to the employed materials provided within Tables 2 and 3 . Table 1 The configuration of these study groups is delineated Table 2 Materials used in this study. Indirect composite resins Lot No Main Matrix Monomers Components Manufacturer Gradia Plus 200211A %1–5 Bis-GMA, 5–10% TEGDMA, 1–5% UDMA Ceramic particls GC Corporation, Tokyo, Japan Ceramage 091948 5–10% UDMA Zirconium silicate %73 Shofu Inc., Kyoto, Japan Tescera ATL 1800007837 TEGDMA, Bis-GMA Amorphous silica, %85 Bisco Inc., Schaumburg, USA LAVA Ultimate N895356 %80 Nano-seramik composite Bis-GMA/ TEGDMA, Silica and zirconia fillers 3M ESPE, St.Paul, MN, USA Scotchbond Universal Etchant 4550701 Fosforik asit %35 Phosphoric acid 3M ESPE GmbH dental Products Neuss, Germany Z250 NC33470 Organic matrix: Bis-GMA, UDMA, Bis-EMA Zirconia/silica filler (0.01–3.5 µm, %82 wt- %60 vol) 3M ESPE, St.Paul, MN, USA Single Bond Universal 00221A 10MDP, fosfat monomer, dimethacrylate resins, HEMA, methacrylate-modified polyalkenoic acid copolymer, filler,ethanol, water, initiator, silane 3M ESPE GmbH dental Products Neuss, Germany Table 3 Composition of different types of resin cement Resin cement Lot No Cement Type Contents Manufacturer RelyX Ultimate 711943 Universal adhesive cement that can be cured both chemically and with light. Methacrylate monomers, silanized fillers, initiators, stabilizers, Dual-cure activators 3M ESPE GmbH dental Products Neuss, Almanya Rely X U200 6716146 Self-adhesive resin cement Matrix: hydroxyethylmethacrylate (HEMA), Bis-GMA Fillers: fluoro alumino silicate glass, zirconium silica 3M ESPE GmbH dental Products Neuss, Germany Shear Bond Strength (SBS) Measurement The Shear Test was conducted using the Shear Testing Machine (MTS Mini-ics, model 858, MTS Corporation, USA). The test involved applying a loading force of 0-400 N at a crosshead speed of 1mm/min. The bond strength was determined by recording the value at the point of failure. The results were then converted from Newton to mPa for statistical analysis. To determine the type of failure, fractured specimens were examined under a stereomicroscope (Olympus SZ51, Edmund Optics®, Inc., Barrington, USA) at ×32 magnification. Three types of failure were defined as follows: Adhesive failure: This occurs when the resin cement completely separates from the composite surface. Cohesive failure: This happens when the resin cement fractures completely. Mixed failure: This is observed when both adhesive and cohesive failures are present simultaneously. These observations were made to understand the nature of failure and assess the performance of the resin cement used in the study. SEM(Scanning Electron Microscopy) Examination Some randomly selected specimens were sputter-coated with gold/palladium and examined with a SEM (Zeis EVO LS 10) (×1000 and x3000). Statistical Analysis The statistical analysis was conducted using SPSS version 24 software (IBM Corp. Armonk, NY, USA). The normality of the data was checked by the ShapiroWilk's test, comparisons of two independent groups that did not show normal distribution were analyzed with Mann-Whitney U test. Chi-square analysis was calculated for double-triple group comparisons. The level of significance was set to p < 0.05. Data availability The datasets analysed during the current study are available from the corresponding author on reasonable request. Results The Mann-Whitney U Test revealed significant differences between the dentin and microhybrid composite groups, as shown in Table 4. The mean shear bond strength value on the dentin surface was measured to be 5.6±2.9 MPa, while on the composite surface it was 9.3±3.5 MPa (p<0.001). These findings indicate that there is a statistically significant difference in the bond strength between the dentin and microhybrid composite groups. The composite surface exhibited a higher mean shear bond strength compared to the dentin surface. Minimum Maximum Mean Std. Dev . Median P Value Dentine Surface 0,85 15,3 5,6 2,9 5,3 0,001** 3M Z250 Micro-hybrid Composite Surface 2,15 19,0 9,3 3,5 9,01 Table 4. Statistical Comparison of Shear Test Results on different surfaces (MPa) The shear bond strengths of indirect composites luted on the dentin surface group with RX-ULT were respectively, CER>TES>GRA>LAVA. Other results were, TES>CER>GRA>LAVA luted with RX-U200 on dentin group and also the same for all other composite surface groups. LAVA showed significantly lower bond strength values for each group and the lowest value for LAVA luted on dentin surface with RX-U200 was 3.02±1.34 MPa (p<0.001). TES showed the highest bond strength at composite surface luted with RX-ULT with 13.17±2.45 MPa (Table 5.) Shear Bond Strength Test Results(MPa) Minimum Maximum Mean Std. Dev. Median Dentine-Tescera RX-U200 1,88 7,47 4,81 1,63 5,35 Dentine-Tescera RX-ULT 1,57 15,28 8,05 3,68 8,05 Dentine-Gradia RX-U200 1,3 5,79 3,62 1,23 4,07 Dentine-Gradia RX-ULT 3,66 12,39 6,98 2,33 6,77 Dentine-Lava RX-U200 0,85 4,35 3,02 1,34 3,51 Dentine-Lava RX-ULT 3,19 13,99 5,69 2,85 5,09 Dentine-Ceramage RX-U200 2,16 6,34 3,3 1,35 2,98 Dentine-Ceramage RX-ULT 5,35 12,45 8,63 2,13 8,12 Composite-Tescera RX-U200 10,04 15,74 12,56 1,84 12,15 Composite-Tescera RX-ULT 9,52 19,03 13,17 2,45 12,93 Composite-Gradia RX-U200 6,12 10,9 8,21 1,37 7,85 Composite-Gradia RX-ULT 5,66 11,74 8,63 1,93 8,94 Composite-Lava RX-U200 2,15 7,2 4,67 1,4 4,68 Composite-Lava RX-ULT 3,03 7,76 5,47 1,59 5,44 Composite-Ceramage RX-U200 5,43 13,44 9,71 2,97 9,66 Composite-Ceramage RX-ULT 8,01 14,85 10,88 2,12 10,45 Table 5. Shear bond strengths of indirect composites (MPa) When we compare the groups according to used resin cements, the results varied depending on the luted surface. There was a highly significant difference between RX-ULT and RX-U200 groups luted on dentin surface.(TableX) Indirect composite groups luted with RX-ULT showed higher bond strength than groups luted with RX-U200 on dentin surfaces(p0.05) (Table 6.) Comparision of Adhesive Cement Type’s Stress Values Stress P Value Dentine - Tescera ( RX-U200-RX-ULT) 0,005* Dentine - Ceramage ( RX-U200-RX-ULT) 0,001** Dentine - Gradia ( RX-U200-RX-ULT) 0,001** Dentine - Lava ( RX-U200-RX-ULT) 0,003* Composite - Tescera ( RX-U200 - RX-ULT) 0,650 Composite - Ceramage ( RX-U200-RX-ULT) 0,443 Composite - Gradia ( RX-U200-RX-ULT) 0,541 Composite - Lava ( RX-U200-RX-ULT) 0,266 Table 6. Statistical Comparison of Different Types of Adhesive Cement Application on dentine and composite groups. Table 7 shows the failure mode distributions of the experimental groups. Adhesive failures were more common in dentin groups, whereas cohesive failures were more common in composite groups. The failure modes for dentin group were 20,6% cohesive failure occured between the dentin and the adhesive resin cement cement, 66,7% adhesive failure occured inside the resin cement and 33.3% mixed failure. For microhybride composite group; 33,3% adhesive failure, 79,4% cohesive failure and 50,2% mixed failure were observed. Dentine Composite(Z-250 Microhybrid) Fracture Type Count % Count % Total p Adhesive 71 66% 35 33% 106 0,001 Cohesive 6 20% 25 80% 31 0,001 Mix 19 35% 36 65% 55 0,001 Total 96 50% 96 50% 192 Table 7. Statistical Evaluation of Fracture Types Representative SEM images of the resin cement/ dentin interface of GRA luted on dentin surface with RX-U200 are shown in Figure 1, CER luted on dentin surface with RX-U200 are shown in Figure 2. The images of resin cement/Z250 Microhybrid composite interface of TES luted on composite surface with RX-ULT are shown in Figure 3 and LAVA luted on composite surface with RX-U200 in Figure 4. The adhesive fracture and remnants of bonding agent in dentin tubules(hybrid layer) can be seen in Figure 2. Discussion The first null hypothesis, which stated that the shear bond strength of traditional and CAD/CAM indirect composite materials would be similar, was rejected. The mean bond strength of Lava™ Ultimate CAD/CAM Block (3M ESPE) was found to be the lowest on both dentin and composite surfaces. Significant research endeavors have been undertaken in the evolution of composite resins within the realm of CAD/CAM systems. These materials have found utility in the fabrication of both provisional restorations and enduring fixed prosthetic solutions. Capitalizing on the progressive advancements in technology, novel and more resilient resin-based restorative materials, adaptable for utilization within computerized frameworks, have emerged. Examples of such materials encompass Lava Ultimate (3M ESPE), Cerasmart (GC), Enamic (Vita), and Tetric CAD (Ivoclar Vivadent), each tailored to harness the benefits of evolving technology 21 , 22 . CAD-CAM composite materials, characterized by a resin matrix interspersed with ceramic particles, can be categorized into two primary groups: resin nano-ceramics and hybrid ceramics. This classification hinges upon the relative proportions of ceramics and composites within their foundational components. Pioneering the realm of resin nano-ceramics is Lava Ultimate, comprised of a composition including 80% nanoceramic composite complexes, BisGMA, TEGDMA, as well as silica and zircon filler particles, as reported in prior studies 21 , 22 . Among the indirect composite materials used, Gradia Indirect has 75% microglass and ceramic fillers, Ceramage has 73% microglass and ceramic fillers, and Tescera ATL has 85% microglass and ceramic fillers. On the other hand, Lava Ultimate consists of 80% nanoceramic composite complexes, silica, and zircon, as well as ceramic filler particles 23 . The disparity in bond strength observed in our study could potentially stem from the variances in the compositions of conventional and CAD/CAM indirect composite materials. Notably, the incorporation of Glassfrit components in Tescera ATL might contribute to its heightened resilience compared to the other composite groups. 23 . Another contributing factor could be the diverse polymerization techniques employed in the composite systems. A multitude of previously documented investigations have underscored that a heightened level of monomer conversion enhances both the physical and chemical attributes of the composite. 24 , 25 . In this study, Gradia indirect composite achieves polymerization solely through light activation, while Ceramage indirect composite undergoes a dual process of polymerization utilizing both heat and light within an oven. Conversely, Lava Ultimate CAD-CAM blocks undergo milling without necessitating an additional polymerization stage. The notable robust bonding values observed in the Tescera ATL group can be ascribed to its unique polymerization method, which involves a pressure oven supplemented with an oxygen scavenger capsule, alongside heat and light exposure throughout the polymerization cycle. As a consequence, this process yields a substantial degree of monomer conversion. Similar to our investigation, Ozakar-Ilda conducted an in vivo study assessing the clinical efficacy of two types of indirect composite inlays in comparison to direct composite restorations over a span of three years. The outcomes of this study revealed a success rate of 93% for Tescera ATL (BISCO, Inc Schaumburg) system indirect inlays, 86% for Brilliant Esthetic Line (Coltène/Whaledent) indirect inlays, and 67% for Valux Plus (3M ESPE) direct composite fillings, based on the modified USPHS criteria. 26 . Similarly, Çetin et al. conducted a five-year evaluation of direct nanofilled and indirect composite resin restorations in posterior teeth, concluding that Tescera ATL received an Alpha score based on the modified USPHS criteria, indicative of excellent performance. 27 , 28 . Two distinct adhesive cement materials were employed within this investigation. The initial adhesive cement, Rely X U200 represents a self-adhesive cement. Conversely, the second material, Rely X Ultimate constitutes a dual-cure cement capable of undergoing both light and chemical curing processes, utilized in tandem with a total etch adhesive system. The secondary hypothesis, which posited similarity in shear bond strength between dual-cure and self-cure adhesive cements, has been partially refuted. Specifically, in the context of dentin surfaces, the indirect composite groups bonded with Rely X Ultimate exhibited superior bond strength in comparison to those connected with Rely X U200 (p < 0.005). In contrast, no statistically significant discrepancy in bond strength emerged between the Rely X Ultimate and Rely X U200 adhesive systems for indirect composite groups bonded onto composite surfaces (p > 0.05). In our obtained results, the shear strength assessments within the experimental group utilizing the total-etch bonding system revealed higher bond strengths for restorations affixed to both dentin and enamel surfaces compared to the self-adhesive system 29 , 30 . The diminished values observed within the groups employing the self-etch resin cement system can be attributed to the inability of self-adhesive resin cements to effectively eliminate the smear layer. Consequently, the formation of a substantial, deep, and robust hybrid layer is compromised. 31 , 32 . Kim et al. conducted an investigation into the impact of cementation methods on the tensile strength of self-adhesive resin cements when bonded to composite blocks. Within the study, CAD/CAM blocks were fabricated, with the initial group being cemented using RelyX Ultimate alongside the conventional Single Bonding agent. In the remaining groups, self-adhesive dual-cure cements, namely RelyX U-200 and G-CEM Cerasmart, were employed. The outcomes of the study revealed that the highest shear strength was observed in the cementation achieved using RelyX Ultimate in conjunction with the Single Bond Universal (3M Espe) bonding agent. 33 . Various investigations have indicated that conventional resin cement exhibits superiority over self-adhesive resin cement concerning aspects such as microleakage and biodegradation. 34 . The final null hypothesis, which postulated that the shear bond strength would be comparable between dentin and composite surfaces, is also refuted based on the outcomes of this study. The shear bond strength measurements on the composite surface surpassed those on dentin across all groups adhered to both dentin and the Z250 microhybrid composite surface using RelyX-U200 and Rely-X Ultimate (p < 0.05). We speculate that the higher bond strength on the composite surface may be due to the formation of polymer-polymer linked bonding between the Z250, a universal resin composite material with a microhybrid structure, and the adhesive resin cement materials. Additionally, we believe that the limited presence of enamel on the surfaces, which are primarily composed of dentin tissue, may resin weak adhesion due to the insufficient formation of the hybrid layer in dentin. When the literature on this subject was examined, no similar study was found. We think that the results we have obtained will be a reference for future studies 30 , 35 . In the present study, our objective was to replicate the Deep Margin Elevation (DME) technique by cementing Z250 microhybrid composite and indirect resin restoration. The findings revealed that the cementation of indirect composite onto an elevated microhybrid composite margin does not lead to a reduction in shear bond strength (SBS); rather, it results in an increase. In their investigation of deep margin elevation, Theisen, Spreafico R., and Müller V. reported that the elevation of the margin did not have a negative impact on the adhesion quality between the restoration and the tooth structure. 36 – 38 . Based on the recent comprehensive review by Eggman et al., which encompasses 38 studies on Deep Margin Elevation, it is indicated that DME does not result in any adverse consequences for the fracture resistance of restored teeth. While there is conflicting evidence regarding the influence of DME on marginal quality, the majority of in vitro studies have reported no detrimental effects. 39 . In numerous studies, surface pretreatment techniques for the DME surface, such as grit blasting, diamond bur finishing, tribochemical silica coating, gentle air-borne particle abrasion with sodium bicarbonate, as well as the application of a silane coupling agent and/or adhesive or a combination of these methods, have been recommended to enhance bond strength. 40 – 45 . In this research, no surface pre-treatment procedures were administered to any specimen to maintain uniformity across all experimental groups. Future inquiries could be pursued to explore the influence of surface conditioning on the bonding strength between diverse surfaces and cement materials. This current investigation was conducted in vitro, and it's important to acknowledge that in vitro studies come with inherent limitations. Prior to the shear bond strength assessment, the specimens were stored in distilled water at 37°C ± 2°C for 24 hours (short-term). However, it's important to note that biodegradation is influenced by a combination of factors, including disintegration and dissolution in saliva, chemical and physical degradation, wear due to occlusal forces, erosion caused by acidic foods and beverages, and bacterial activity. 46 Øilo pointed out that the degradation of composite materials and bonding agents in the oral cavity involves a complex interaction process that cannot be fully replicated in vitro. Therefore, it's essential to acknowledge the limitations of simulating the oral environment in this in vitro study. 46 Conclusion 1.Adhesive resin cement systems with acid etching and bonding application exhibited higher shear bond strength than self-adhesive cement systems. 2. Indirect restoration materials showed a much better SBS on the microhybrid composite than on the dentine surface. The Deep Margin Elevation(DME) process performed in very deep cavities not only eliminates the problems that may occur during the cementation of the indirect restoration, but also allows long-lasting restorations to be obtained with high bond strength. 3. Tescera ATL showed the highest SBS among the indirect composite groups. 4. Lava Ultimate showed the lowest SBS value among the indirect composite groups. 5. According to the fracture types examinations with stereomicroscope, it was observed that the most cohesive type fracture was observed in the Z250 microhybrid composite groups, while the adhesive type fracture occurred in the dentine groups. Declarations Competing interests The authors declare no competing interests. Author Contribution OEB,OY and EK wrote the main manuscript text. OE and EK prepared figures. BIG, OE, EK and OY were obtained special molds for fixing the samples in the shear testing device. OE, FY and SEB were recorded data by performing the shear bond test in the Laboratory of the Faculty of Mechanical Engineering. All authors have substantially revised the manuscript and done the final editing; all authors have read and agreed to the published version of the manuscript. Acknowledgements To Dr. Oktay Yazıcıoglu for providing valuable supports and leading for the present research. Additional information Correspondence and requests for materials should be addressed to OEB. Reprints and permissions information is available at www.nature.com/reprints. Publisher’s note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional afliations. References Mount, G. J. & Ngo, H. Minimal intervention: Advanced lesions. Quintessence International 31 (2000). Haralur, S. B., Al-Qahtani, A. S., Al-Qarni, M. M., Al-Homrany, R. M. & Aboalkhair, A. E. 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P. et al. Two-year clinical performance of a nanofiller vs a fine-particle hybrid resin composite. Clin Oral Investig 10 , 119-125, doi:10.1007/s00784-006-0041-8 (2006). Kansal, R., Rani, S., Kumar, M., Kumar, S. & Issar, G. Comparative Evaluation of Shear Bond Strength of Newer Resin Cement (RelyX Ultimate and RelyX U200) to Lithium Disilicate and Zirconia Ceramics as Influenced by Thermocycling. Contemp Clin Dent 9 , 601-606, doi:10.4103/ccd.ccd_601_18 (2018). Zorba, Y. O., Ilday, N. O., Bayındır, Y. Z. & Demirbuga, S. Comparing the shear bond strength of direct and indirect composite inlays in relation to different surface conditioning and curing techniques. Eur J Dent 7 , 436-441, doi:10.4103/1305-7456.120679 (2013). Zhang, C. & Degrange, M. Shear bond strengths of self-adhesive luting resins fixing dentine to different restorative materials. J Biomater Sci Polym Ed 21 , 593-608, doi:10.1163/156856209x431640 (2010). Bottino, M. A. et al. Bonding of Y-TZP to dentin: effects of Y-TZP surface conditioning, resin cement type, and aging. Oper Dent 39 , 291-300, doi:10.2341/12-235-l (2014). Kim, J. Y., Cho, G. Y., Roh, B. D. & Shin, Y. Effect of Curing Mode on Shear Bond Strength of Self-Adhesive Cement to Composite Blocks. Materials (Basel) 9 , doi:10.3390/ma9030210 (2016). Liu, Q., Meng, X., Yoshida, K. & Luo, X. Bond degradation behavior of self-adhesive cement and conventional resin cements bonded to silanized ceramic. J Prosthet Dent 105 , 177-184, doi:10.1016/s0022-3913(11)60026-7 (2011). Sibai, N., El Mourad, A., Al Suhaibani, N., Al Ahmadi, R. & Al Dosary, S. Shear Bond Strength of Self-Adhesive Flowable Resin Composite. International Journal of Dentistry 2022 , 6280624, doi:10.1155/2022/6280624 (2022). Theisen, C. E. R. et al. Quality of CAD-CAM inlays placed on aged resin-based composite restorations used as deep margin elevation: a laboratory study. Clinical Oral Investigations , doi:10.1007/s00784-022-04841-y (2023). Spreafico, R. et al. Evaluation of the In Vitro Effects of Cervical Marginal Relocation Using Composite Resins on the Marginal Quality of CAD/CAM Crowns. J Adhes Dent 18 , 355-362, doi:10.3290/j.jad.a36514 (2016). Müller, V. et al. Influence of proximal box elevation technique on marginal integrity of adhesively luted Cerec inlays. Clin Oral Investig 21 , 607-612, doi:10.1007/s00784-016-1927-8 (2017). Eggmann, F., Ayub, J. M., Conejo, J. & Blatz, M. B. Deep margin elevation—Present status and future directions. Journal of Esthetic and Restorative Dentistry 35 , 26-47, doi:10.1111/jerd.13008 (2023). Da Silva, D., Ceballos, L. & Fuentes, M. V. Influence of the adhesive strategy in the sealing ability of resin composite inlays after deep margin elevation. J Clin Exp Dent 13 , e886-e893, doi:10.4317/jced.58689 (2021). Dietschi, D. & Spreafico, R. Evidence-based concepts and procedures for bonded inlays and onlays. Part III. A case series with long-term clinical results and follow-up. Int J Esthet Dent 14 , 118-133 (2019). Bresser, R. A. et al. Influence of Deep Margin Elevation and preparation design on the fracture strength of indirectly restored molars. J Mech Behav Biomed Mater 110 , 103950, doi:10.1016/j.jmbbm.2020.103950 (2020). Ilgenstein, I. et al. Influence of proximal box elevation on the marginal quality and fracture behavior of root-filled molars restored with CAD/CAM ceramic or composite onlays. Clin Oral Investig 19 , 1021-1028, doi:10.1007/s00784-014-1325-z (2015). Sandoval, M. J., Rocca, G. T., Krejci, I., Mandikos, M. & Dietschi, D. In vitro evaluation of marginal and internal adaptation of class II CAD/CAM ceramic restorations with different resinous bases and interface treatments. Clin Oral Investig 19 , 2167-2177, doi:10.1007/s00784-015-1449-9 (2015). Zhang, H. et al. Effect of proximal box elevation on fracture resistance and microleakage of premolars restored with ceramic endocrowns. PLoS One 16 , e0252269, doi:10.1371/journal.pone.0252269 (2021). Øilo, G. Biodegradation of Dental Composites/ Glass-Ionomer Cements. Advances in Dental Research 6 , 50-54, doi:10.1177/08959374920060011701 (1992). Additional Declarations No competing interests reported. Cite Share Download PDF Status: Posted Version 1 posted You are reading this latest preprint version Research Square lets you share your work early, gain feedback from the community, and start making changes to your manuscript prior to peer review in a journal. As a division of Research Square Company, we’re committed to making research communication faster, fairer, and more useful. We do this by developing innovative software and high quality services for the global research community. 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Also discoverable on Platform About Our Team In Review Editorial Policies Advisory Board Help Center Resources Author Services Accessibility API Access RSS feed Manage Cookie Preferences © Research Square 2026 | ISSN 2693-5015 (online) Privacy Policy Terms of Service Do Not Sell My Personal Information {"props":{"pageProps":{"initialData":{"identity":"rs-3821900","acceptedTermsAndConditions":true,"allowDirectSubmit":true,"archivedVersions":[],"articleType":"Article","associatedPublications":[],"authors":[{"id":264709816,"identity":"cdbdcf38-30c0-4436-afcd-8d448eae5ab2","order_by":0,"name":"Oyun Erdene 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Kıtın","email":"","orcid":"","institution":"İstanbul University","correspondingAuthor":false,"prefix":"","firstName":"Emine","middleName":"","lastName":"Kıtın","suffix":""},{"id":264709819,"identity":"bfcdb547-6299-4c51-879f-7b5272d5a463","order_by":3,"name":"Burç İhsan Gençel","email":"","orcid":"","institution":"Cerrahpaşa-İstanbul University","correspondingAuthor":false,"prefix":"","firstName":"Burç","middleName":"İhsan","lastName":"Gençel","suffix":""},{"id":264709820,"identity":"89dca636-54fa-4c39-8840-ac4d37316179","order_by":4,"name":"Fatih Yamak","email":"","orcid":"","institution":"İstanbul Technical University","correspondingAuthor":false,"prefix":"","firstName":"Fatih","middleName":"","lastName":"Yamak","suffix":""},{"id":264709821,"identity":"1b11adc1-0568-46d8-8463-7df140b5cca4","order_by":5,"name":"Süreyya Ergün Bozdağ","email":"","orcid":"","institution":"İstanbul Technical University","correspondingAuthor":false,"prefix":"","firstName":"Süreyya","middleName":"Ergün","lastName":"Bozdağ","suffix":""}],"badges":[],"createdAt":"2023-12-29 16:44:10","currentVersionCode":1,"declarations":"","doi":"10.21203/rs.3.rs-3821900/v1","doiUrl":"https://doi.org/10.21203/rs.3.rs-3821900/v1","draftVersion":[],"editorialEvents":[],"editorialNote":"","failedWorkflow":false,"files":[{"id":49100497,"identity":"a37ff48f-172a-478d-8271-9c5da0923a17","added_by":"auto","created_at":"2024-01-03 05:31:44","extension":"jpeg","order_by":1,"title":"Figure 1","display":"","copyAsset":false,"role":"figure","size":29957,"visible":true,"origin":"","legend":"\u003cp\u003e\u003cstrong\u003eRepresentative SEM images of the resin cement/ dentin interface of GRA luted on dentin surface with RX-U200 are shown in Figure 1.\u003c/strong\u003e\u003c/p\u003e","description":"","filename":"Figure1..jpeg","url":"https://assets-eu.researchsquare.com/files/rs-3821900/v1/2bdf37d3218622efc845fb76.jpeg"},{"id":49100670,"identity":"12fff607-12a6-45d0-9901-b07382cb9285","added_by":"auto","created_at":"2024-01-03 05:39:44","extension":"jpeg","order_by":2,"title":"Figure 2","display":"","copyAsset":false,"role":"figure","size":33374,"visible":true,"origin":"","legend":"\u003cp\u003e\u003cstrong\u003eThe SEM images CER luted on dentin surface with RX-U200 are shown in Figure 2.\u003c/strong\u003e\u003c/p\u003e","description":"","filename":"Figure2..jpeg","url":"https://assets-eu.researchsquare.com/files/rs-3821900/v1/8c297ead9fa5c42ab48153f0.jpeg"},{"id":49100499,"identity":"1cbcc979-ae5d-43b7-8fa0-61541e640a6b","added_by":"auto","created_at":"2024-01-03 05:31:44","extension":"jpeg","order_by":3,"title":"Figure 3","display":"","copyAsset":false,"role":"figure","size":28882,"visible":true,"origin":"","legend":"\u003cp\u003e\u003cstrong\u003eThe SEM images of resin cement/Z250 Microhybrid composite interface of TES luted on composite surface with RX-ULT are shown in Figure 3.\u003c/strong\u003e\u003c/p\u003e","description":"","filename":"Figure3..jpeg","url":"https://assets-eu.researchsquare.com/files/rs-3821900/v1/129fba3bb311b159c8023e82.jpeg"},{"id":49100498,"identity":"23b62f75-e18b-4d01-a60b-60f9e8257057","added_by":"auto","created_at":"2024-01-03 05:31:44","extension":"jpeg","order_by":4,"title":"Figure 4","display":"","copyAsset":false,"role":"figure","size":28163,"visible":true,"origin":"","legend":"\u003cp\u003e\u003cstrong\u003eThe SEM images of LAVA luted on composite surface with RX-U200 are shown in Figure 4.\u003c/strong\u003e\u003c/p\u003e","description":"","filename":"Figure4..jpeg","url":"https://assets-eu.researchsquare.com/files/rs-3821900/v1/929b1f444c88b50fc6134a39.jpeg"},{"id":52022035,"identity":"f3b0e64d-09c8-4c8c-b774-2baa1df6bc2d","added_by":"auto","created_at":"2024-03-05 15:00:23","extension":"pdf","order_by":0,"title":"","display":"","copyAsset":false,"role":"manuscript-pdf","size":802931,"visible":true,"origin":"","legend":"","description":"","filename":"manuscript.pdf","url":"https://assets-eu.researchsquare.com/files/rs-3821900/v1/e8be5b32-1cf2-4085-9cef-153c7061ee26.pdf"}],"financialInterests":"No competing interests reported.","formattedTitle":"Comparison of Bond Strength of Different Indirect Composite Systems and CAD/CAM Composite Blocks between Dentin and Composite Surfaces: An in vitro study","fulltext":[{"header":"Introduction","content":"\u003cp\u003eAs the trend towards minimally invasive approaches continues to gain traction, the progress in adhesive dentistry is progressively piquing interest. Employing minimally invasive techniques for tooth preparation serves the purpose of minimizing failures in both dental hard tissues and pulp tissue, thereby safeguarding the residual tooth structure and optimizing the natural functional capacities of the teeth to their utmost potential\u003csup\u003e\u003cspan citationid=\"CR1\" class=\"CitationRef\"\u003e1\u003c/span\u003e\u003c/sup\u003e. Numerous contemporary studies have consistently indicated that the conservation of intact tooth tissue significantly correlates with the longevity of dental restorations and overall tooth integrity \u003csup\u003e\u003cspan additionalcitationids=\"CR3\" citationid=\"CR2\" class=\"CitationRef\"\u003e2\u003c/span\u003e\u0026ndash;\u003cspan citationid=\"CR4\" class=\"CitationRef\"\u003e4\u003c/span\u003e\u003c/sup\u003e.\u003c/p\u003e \u003cp\u003eIndirect restorations represent a therapeutic modality utilized for the restitution of the innate anatomical morphology, longevity, and esthetic qualities of teeth, particularly in addressing the loss of dental substrate attributable to caries or fractures in the posterior dentition. Posterior indirect restorations categorically encompass three delineations, namely inlay, onlay, and overlay, each predicated on the extent of the cavity's dimensions. Inlay restorations entail the rehabilitation of occlusal, proximal, and gingival cavities, yet without complete encasement of the occlusal surface. Onlay restorations, in contrast, entail the coverage of the occlusal surface as well as one or more cusps. Overlay restorations extend further, encapsulating the entire occlusal surface alongside tubercles, thereby enveloping the buccal and lingual facets of the clinical crown as well \u003csup\u003e\u003cspan citationid=\"CR5\" class=\"CitationRef\"\u003e5\u003c/span\u003e,\u003cspan citationid=\"CR6\" class=\"CitationRef\"\u003e6\u003c/span\u003e\u003c/sup\u003e.\u003c/p\u003e \u003cp\u003eInherent within the direct technique employing composite materials, the potential for complications such as polymerization shrinkage exists. Conversely, in the context of the indirect approach, the polymerization shrinkage associated with laboratory-based composite materials or ceramic restorations is confined to the utilization of the resin cement \u003csup\u003e\u003cspan citationid=\"CR7\" class=\"CitationRef\"\u003e7\u003c/span\u003e\u003c/sup\u003e Consequently, the drawbacks stemming from polymerization shrinkage within indirect restorations are effectively mitigated, thereby minimizing the prospect of suboptimal outcomes concerning interproximal contact points, occlusal morphological features, and marginal edge congruence \u003csup\u003e\u003cspan citationid=\"CR8\" class=\"CitationRef\"\u003e8\u003c/span\u003e\u003c/sup\u003e.\u003c/p\u003e \u003cp\u003eThrough an analysis of 11 scholarly investigations within the field, researchers have concluded that indirect restorative procedures yield superior preservation of both form and function when compared to direct restorations, particularly in cases involving significant loss of dental structure and tissue. These studies employed adhesion techniques utilizing dual-cure resin cements, offering a combination of mechanical interlocking and chemical bonding. When successful adhesion was achieved, it was observed that an exceptional level of fracture resistance was achieved through the intricate interplay between the irregular surface features within the cement and the restoration. These findings also underscored the attainment of outstanding bond strength and a notable deterrence against the propagation of potential fractures. \u003csup\u003e\u003cspan additionalcitationids=\"CR10 CR11 CR12 CR13\" citationid=\"CR9\" class=\"CitationRef\"\u003e9\u003c/span\u003e\u0026ndash;\u003cspan citationid=\"CR14\" class=\"CitationRef\"\u003e14\u003c/span\u003e\u003c/sup\u003e.\u003c/p\u003e \u003cp\u003eVarious methodologies exist for the fabrication of indirect restorations. The CAD/CAM (computer-aided design-computer-aided manufacturing) technique, which involves the utilization of optical reader cameras for processing scanned images in a computerized environment, was introduced by Bruce Altschuler of the United States in 1977. The incorporation of CAD/CAM technology into restorative dentistry can be traced back to the 1980s. In 1984, Francois Duret of France advanced the Duret system, named after himself, offering a more comprehensive single-member restoration approach. Subsequently, in 1988, Werner M\u0026ouml;rmann and Marco Brandestini of Switzerland introduced the pioneering dental CAD/CAM application, enhancing parameters related to production, feasibility, and cost-effectiveness with the Cerec system \u003csup\u003e\u003cspan citationid=\"CR15\" class=\"CitationRef\"\u003e15\u003c/span\u003e\u003c/sup\u003e.\u003c/p\u003e \u003cp\u003eThe goal is to achieve enduring clinical success in dentistry through the continuous advancement of ceramic and composite blocks facilitated by CAD/CAM technology. Recent progress in materials science has ushered in a new era, yielding laboratory-fabricated indirect composite resins that are suitable for both indirect restorations and direct composite resins. These materials are crafted extracorally and subsequently polymerized within a controlled laboratory setting. Consequently, they offer the flexibility to employ various polymerization techniques such as high-energy ultraviolet light, heat, and pressure \u003csup\u003e\u003cspan citationid=\"CR16\" class=\"CitationRef\"\u003e16\u003c/span\u003e,\u003cspan citationid=\"CR17\" class=\"CitationRef\"\u003e17\u003c/span\u003e\u003c/sup\u003e.\u003c/p\u003e \u003cp\u003eThe enduring triumph of indirect composite resin restorations is intricately linked with the efficacious establishment of adhesion between the dental substrate and the restoration. Despite the multitude of adhesive choices available today, self-adhesive resin cements have been introduced to the clinical arena, aiming to curtail and mitigate potential procedural errors. While self-adhesive resin cements, designed for direct application devoid of a separate acid-etching and bonding step, offer a streamlined approach, debates persist surrounding their bond strength when contrasted with alternative etch-and-rinse and self-etch adhesive resin cements \u003csup\u003e\u003cspan citationid=\"CR18\" class=\"CitationRef\"\u003e18\u003c/span\u003e,\u003cspan citationid=\"CR19\" class=\"CitationRef\"\u003e19\u003c/span\u003e\u003c/sup\u003e.\u003c/p\u003e \u003cp\u003eThis in vitro investigation was undertaken to juxtapose the shear bond strength exhibited by distinct indirect composite materials, as affixed to both dentin and composite surfaces, utilizing varying adhesive resin cements. The formulated null hypotheses were as follows: 1. Comparable shear bond strength would be observed between traditional and CAD/CAM indirect composite materials. 2. Similar shear bond strength would be evident between dual-cure and self-cure adhesive cements. 3. The shear bond strength would exhibit parity on both dentin and composite surfaces.\u003c/p\u003e"},{"header":"Methods","content":"\u003cdiv id=\"Sec3\" class=\"Section2\"\u003e \u003ch2\u003eEthics information\u003c/h2\u003e \u003cp\u003eThis study was approved by the Istanbul University Faculty of Dentistry Clinical Research Ethics Committee on February 19, 2020, with the approval number (No. 2020/6-REV2) and was supported by the Istanbul University Scientific Research Project (Project No: TDK-2020-36980) The shear bond strength test was carried out following the guidelines of ISO/TS 11405:2003. \u003csup\u003e\u003cspan citationid=\"CR20\" class=\"CitationRef\"\u003e20\u003c/span\u003e\u003c/sup\u003e\u003c/p\u003e \u003c/div\u003e \u003cdiv id=\"Sec4\" class=\"Section2\"\u003e \u003ch2\u003eDentin Surface Preparation\u003c/h2\u003e \u003cp\u003eForty-eight recently extracted human molar teeth, devoid of caries, restorations, fractures, and root canal interventions, underwent meticulous cleansing to eliminate both calculus and periodontal soft tissues. Subsequently, these teeth were immersed in a 0.1% thymol solution and stored under refrigeration at 4\u0026deg;C, for a duration not exceeding six months following extraction, spanning the duration of the assessment period. Teeth were embedded completely in autopolymerizing acrylic resin using a custom-made silicon mold and teeht were cut 2-3mm below the dentinoenamel junction using a round-ended tapered diamond bladed low-speed rotary microtome under water cooling. (Isomet 1000 Buehler Precision Saw, D\u0026uuml;sseldorf, Germany). To establish a standardized and even dentin surface, the dentin facets of all utilized teeth were meticulously refined for a duration of 60 seconds with 600-grit silicon carbide papers (Buehler), while maintaining continuous water cooling(Buehler, D\u0026uuml;sseldorf, Germany).\u003c/p\u003e \u003c/div\u003e \u003cdiv id=\"Sec5\" class=\"Section2\"\u003e \u003ch2\u003eComposite Surface Preparation\u003c/h2\u003e \u003cp\u003eA total of forty-eight composite surfaces, each measuring 4x2mm in a disc-shaped format, were fabricated using the Z250 Microhybrid composite (3M Espe, USA) material. A custom-designed metal mold was employed to create a negative impression, from which a silicone mold was generated. These composite discs were meticulously prepared using a horizontal layering technique and subsequently polymerized for 20 seconds with an LED light curing device (Demi Ultra LED Curing Light, Kerr).\u003c/p\u003e \u003c/div\u003e \u003cdiv id=\"Sec6\" class=\"Section2\"\u003e \u003ch2\u003ePreparation of Indirect Composite Specimens\u003c/h2\u003e \u003cp\u003eLava\u0026trade; Ultimate CAD/CAM Block(3M Espe, St.Paul,MN,ABD)\u003c/p\u003e \u003cp\u003eCylindrical samples with dimensions of 10x3 mm (10 mm in height, 3 mm in diameter) were created through the utilization of a CAD (Computer-Aided Design) software program. These prototypes were then translated into physical entities using a CAM (Computer-Aided Manufacturing) process, employing a Lava\u0026trade; Ultimate (3M Espe, St.Paul,MN,ABD) nanoceramic-based resin composite block. Subsequently, the 10x3 mm cylindrical samples were sectioned into thirds, resulting in cylindrical samples measuring 3x3 mm, utilizing a low-speed rotary microtome under continuous water cooling. (Isomet 1000 Buehler Precision Saw, D\u0026uuml;sseldorf, Germany).\u003c/p\u003e \u003c/div\u003e \u003cdiv id=\"Sec7\" class=\"Section2\"\u003e \u003ch2\u003eGradia Plus(GC Corporation, Tokyo, Japan)\u003c/h2\u003e \u003cp\u003eA custom Teflon mold was designed to create cylindrical composite samples measuring 3x3mm. Subsequently, Gradia indirect composite was condensed into the Teflon mold using small pieces measuring 1mm with the assistance of cement fulvar. The condensed composite was pre-polymerized for 10 seconds using the GC steplight SL-1 device. Finally, the samples, which were polymerized using the layering method, were polymerized for a total of 3 minutes using the GC Labolight LV-III device.\u003c/p\u003e \u003cp\u003e \u003cb\u003eTescera ATL(Bisco Inc., Schaumburg, IL, USA).\u003c/b\u003e \u003c/p\u003e \u003cp\u003eA custom Teflon mold was designed to create cylindrical composite samples measuring 3x3mm. Subsequently, Tescera ATL indirect composite was condensed into the Teflon mold using small pieces measuring 1mm with the assistance of cement fulvar. The condensed composite was polymerized using an LED light device. The polymerization process was completed in a Tescera ATL light cup with pressure and light for 2 minutes. The final polymerization was carried out using the Tescera ATL Pressure/Light/Heat Cure Cup (Bisco Inc., Schaumburg, IL, USA) for 10\u0026ndash;13 minutes with an oxygen scavenger capsule. All Tescera ATL samples were subjected to this process.\u003c/p\u003e \u003c/div\u003e \u003cdiv id=\"Sec8\" class=\"Section2\"\u003e \u003ch2\u003eCeramage Body(Shofu Inc., Kyoto, Japan)\u003c/h2\u003e \u003cp\u003eA custom Teflon mold was designed to create cylindrical composite samples measuring 3x3mm. Subsequently, Ceramage Body (Shofu Inc., Kyoto, Japan) indirect composite was condensed into the Teflon mold using small pieces measuring 1mm with the assistance of cement fulvar. The condensed composite was pre-polymerized with the Sublite V device for 20 seconds. The samples, which were polymerized using the layering method, were polymerized for 5 minutes with the Solidilite V device. All Ceramage samples have been subjected to this process.\u003c/p\u003e \u003c/div\u003e \u003cdiv id=\"Sec9\" class=\"Section2\"\u003e \u003ch2\u003eCementation procedure\u003c/h2\u003e \u003cp\u003eUltradent Bonding Apparatus of UltraTester\u0026trade; Bond Strength Testing Machine(Ultradent Products, Inc.) was used to standardize the cementation procedure. Acrylic blocks with dentin and Z250 microhybride composite disc surfaces were fixed to Ultradent Bonding Apparatus. Two indirect composite samples were then luted to each disc surface with a standart force (500\u0026thinsp;\u0026plusmn;\u0026thinsp;50 gr) wighed with precision balance.\u003c/p\u003e \u003cp\u003eFor the eight Rely X-U200(3M ESPE, St. Paul, MN, USA) self-adhesive resin cement group; indirect composite samples were bonded to dentin and 3M Z250 microhybrid composite disc surfaces with direct cement application. Subsequently, polymerization was executed in strict adherence to the manufacturer's instructions, employing the Demi Ultra LED light device (Curing Light, Kerr). In the RelyX Ultimate adhesive resin cement group, Scotchbond Universal Etch(3M ESPE, St. Paul, MN, USA) acid was applied for 15sn to both dentin and 3M Z250 microhybrid composite disc surfaces. Then, Single Bond Universal(3M ESPE) adhesive system applied and polymerized with Demi Ultra LED light device (Curing Light, Kerr). Finally, RelyX Ultimate adhesive resin cement was applied according to the manufacturer's instructions and cured with the same light device. After cementation samples were stored in distilled water at 37\u0026deg;C for 24h.\u003c/p\u003e \u003cdiv id=\"Sec10\" class=\"Section3\"\u003e \u003ch2\u003eStudy Groups\u003c/h2\u003e \u003cp\u003eThe specimens were stratified into sixteen distinct groups based on the type of surface being cemented and the specific adhesive cement system employed. The configuration of these study groups is delineated in Table\u0026nbsp;\u003cspan refid=\"Tab1\" class=\"InternalRef\"\u003e1\u003c/span\u003e, with comprehensive details pertaining to the employed materials provided within Tables\u0026nbsp;\u003cspan refid=\"Tab2\" class=\"InternalRef\"\u003e2\u003c/span\u003e and \u003cspan refid=\"Tab3\" class=\"InternalRef\"\u003e3\u003c/span\u003e.\u003c/p\u003e \u003cp\u003eTable 1 The configuration of these study groups is delineated\u003c/p\u003e \u003cp\u003e\u003cimg 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\"\u003e\u003cbr\u003e\u003c/p\u003e\u003cp\u003e \u003cdiv class=\"gridtable\"\u003e\u003ctable float=\"Yes\" id=\"Tab2\" border=\"1\"\u003e \u003ccaption language=\"En\"\u003e \u003cdiv class=\"CaptionNumber\"\u003eTable 2\u003c/div\u003e \u003cdiv class=\"CaptionContent\"\u003e \u003cp\u003eMaterials used in this study.\u003c/p\u003e \u003c/div\u003e \u003c/caption\u003e \u003ccolgroup cols=\"5\"\u003e \u003cdiv align=\"left\" class=\"colspec\" colname=\"c1\" colnum=\"1\"\u003e\u003c/div\u003e \u003cdiv align=\"left\" class=\"colspec\" colname=\"c2\" colnum=\"2\"\u003e\u003c/div\u003e \u003cdiv align=\"left\" class=\"colspec\" colname=\"c3\" colnum=\"3\"\u003e\u003c/div\u003e \u003cdiv align=\"left\" class=\"colspec\" colname=\"c4\" colnum=\"4\"\u003e\u003c/div\u003e \u003cdiv align=\"left\" class=\"colspec\" colname=\"c5\" colnum=\"5\"\u003e\u003c/div\u003e \u003cthead\u003e \u003ctr\u003e \u003cth align=\"left\" colname=\"c1\"\u003e \u003cp\u003eIndirect composite resins\u003c/p\u003e \u003c/th\u003e \u003cth align=\"left\" colname=\"c2\"\u003e \u003cp\u003eLot No\u003c/p\u003e \u003c/th\u003e \u003cth align=\"left\" colname=\"c3\"\u003e \u003cp\u003eMain Matrix Monomers\u003c/p\u003e \u003c/th\u003e \u003cth align=\"left\" colname=\"c4\"\u003e \u003cp\u003eComponents\u003c/p\u003e \u003c/th\u003e \u003cth align=\"left\" colname=\"c5\"\u003e \u003cp\u003eManufacturer\u003c/p\u003e \u003c/th\u003e \u003c/tr\u003e \u003c/thead\u003e \u003ctbody\u003e \u003ctr\u003e \u003ctd align=\"left\" colname=\"c1\"\u003e \u003cp\u003e\u003cb\u003eGradia Plus\u003c/b\u003e\u003c/p\u003e \u003c/td\u003e \u003ctd align=\"left\" colname=\"c2\"\u003e \u003cp\u003e200211A\u003c/p\u003e \u003c/td\u003e \u003ctd align=\"left\" colname=\"c3\"\u003e \u003cp\u003e%1\u0026ndash;5 Bis-GMA, 5\u0026ndash;10% TEGDMA,\u003c/p\u003e \u003cp\u003e1\u0026ndash;5% UDMA\u003c/p\u003e \u003c/td\u003e \u003ctd align=\"left\" colname=\"c4\"\u003e \u003cp\u003eCeramic particls\u003c/p\u003e \u003c/td\u003e \u003ctd align=\"left\" colname=\"c5\"\u003e \u003cp\u003eGC Corporation, Tokyo, Japan\u003c/p\u003e \u003c/td\u003e \u003c/tr\u003e \u003ctr\u003e \u003ctd align=\"left\" colname=\"c1\"\u003e \u003cp\u003e\u003cb\u003eCeramage\u003c/b\u003e\u003c/p\u003e \u003c/td\u003e \u003ctd align=\"left\" colname=\"c2\"\u003e \u003cp\u003e091948\u003c/p\u003e \u003c/td\u003e \u003ctd align=\"left\" colname=\"c3\"\u003e \u003cp\u003e5\u0026ndash;10% UDMA\u003c/p\u003e \u003c/td\u003e \u003ctd align=\"left\" colname=\"c4\"\u003e \u003cp\u003eZirconium silicate %73\u003c/p\u003e \u003c/td\u003e \u003ctd align=\"left\" colname=\"c5\"\u003e \u003cp\u003eShofu Inc., Kyoto, Japan\u003c/p\u003e \u003c/td\u003e \u003c/tr\u003e \u003ctr\u003e \u003ctd align=\"left\" colname=\"c1\"\u003e \u003cp\u003e\u003cb\u003eTescera ATL\u003c/b\u003e\u003c/p\u003e \u003c/td\u003e \u003ctd align=\"left\" colname=\"c2\"\u003e \u003cp\u003e1800007837\u003c/p\u003e \u003c/td\u003e \u003ctd align=\"left\" colname=\"c3\"\u003e \u003cp\u003eTEGDMA, Bis-GMA\u003c/p\u003e \u003c/td\u003e \u003ctd align=\"left\" colname=\"c4\"\u003e \u003cp\u003eAmorphous silica, %85\u003c/p\u003e \u003c/td\u003e \u003ctd align=\"left\" colname=\"c5\"\u003e \u003cp\u003eBisco Inc., Schaumburg, USA\u003c/p\u003e \u003c/td\u003e \u003c/tr\u003e \u003ctr\u003e \u003ctd align=\"left\" colname=\"c1\"\u003e \u003cp\u003e\u003cb\u003eLAVA Ultimate\u003c/b\u003e\u003c/p\u003e \u003c/td\u003e \u003ctd align=\"left\" colname=\"c2\"\u003e \u003cp\u003eN895356\u003c/p\u003e \u003c/td\u003e \u003ctd align=\"left\" colname=\"c3\"\u003e \u003cp\u003e%80 Nano-seramik composite Bis-GMA/ TEGDMA,\u003c/p\u003e \u003c/td\u003e \u003ctd align=\"left\" colname=\"c4\"\u003e \u003cp\u003eSilica and zirconia fillers\u003c/p\u003e \u003c/td\u003e \u003ctd align=\"left\" colname=\"c5\"\u003e \u003cp\u003e3M ESPE, St.Paul, MN, USA\u003c/p\u003e \u003c/td\u003e \u003c/tr\u003e \u003ctr\u003e \u003ctd align=\"left\" colname=\"c1\"\u003e \u003cp\u003e\u003cb\u003eScotchbond Universal Etchant\u003c/b\u003e\u003c/p\u003e \u003c/td\u003e \u003ctd align=\"left\" colname=\"c2\"\u003e \u003cp\u003e4550701\u003c/p\u003e \u003c/td\u003e \u003ctd align=\"left\" colname=\"c3\"\u003e \u003cp\u003eFosforik asit\u003c/p\u003e \u003c/td\u003e \u003ctd align=\"left\" colname=\"c4\"\u003e \u003cp\u003e%35 Phosphoric acid\u003c/p\u003e \u003c/td\u003e \u003ctd align=\"left\" colname=\"c5\"\u003e \u003cp\u003e3M ESPE GmbH dental Products Neuss, Germany\u003c/p\u003e \u003c/td\u003e \u003c/tr\u003e \u003ctr\u003e \u003ctd align=\"left\" colname=\"c1\"\u003e \u003cp\u003e\u003cb\u003eZ250\u003c/b\u003e\u003c/p\u003e \u003c/td\u003e \u003ctd align=\"left\" colname=\"c2\"\u003e \u003cp\u003eNC33470\u003c/p\u003e \u003c/td\u003e \u003ctd align=\"left\" colname=\"c3\"\u003e \u003cp\u003eOrganic matrix: Bis-GMA, UDMA, Bis-EMA\u003c/p\u003e \u003c/td\u003e \u003ctd align=\"left\" colname=\"c4\"\u003e \u003cp\u003eZirconia/silica filler (0.01\u0026ndash;3.5 \u0026micro;m, %82 wt- %60 vol)\u003c/p\u003e \u003c/td\u003e \u003ctd align=\"left\" colname=\"c5\"\u003e \u003cp\u003e3M ESPE, St.Paul, MN, USA\u003c/p\u003e \u003c/td\u003e \u003c/tr\u003e \u003ctr\u003e \u003ctd align=\"left\" colname=\"c1\"\u003e \u003cp\u003e\u003cb\u003eSingle Bond\u003c/b\u003e\u003c/p\u003e \u003cp\u003e\u003cb\u003eUniversal\u003c/b\u003e\u003c/p\u003e \u003c/td\u003e \u003ctd align=\"left\" colname=\"c2\"\u003e \u003cp\u003e00221A\u003c/p\u003e \u003c/td\u003e \u003ctd align=\"left\" colspan=\"2\" nameend=\"c4\" namest=\"c3\"\u003e \u003cp\u003e10MDP, fosfat monomer,\u003c/p\u003e \u003cp\u003edimethacrylate resins,\u003c/p\u003e \u003cp\u003eHEMA,\u003c/p\u003e \u003cp\u003emethacrylate-modified\u003c/p\u003e \u003cp\u003epolyalkenoic acid copolymer,\u003c/p\u003e \u003cp\u003efiller,ethanol,\u003c/p\u003e \u003cp\u003ewater, initiator, silane\u003c/p\u003e \u003c/td\u003e \u003ctd align=\"left\" colname=\"c5\"\u003e \u003cp\u003e3M ESPE GmbH dental Products Neuss, Germany\u003c/p\u003e \u003c/td\u003e \u003c/tr\u003e \u003c/tbody\u003e \u003c/colgroup\u003e \u003c/table\u003e\u003c/div\u003e \u003c/p\u003e \u003cp\u003e \u003cdiv class=\"gridtable\"\u003e\u003ctable float=\"Yes\" id=\"Tab3\" border=\"1\"\u003e \u003ccaption language=\"En\"\u003e \u003cdiv class=\"CaptionNumber\"\u003eTable 3\u003c/div\u003e \u003cdiv class=\"CaptionContent\"\u003e \u003cp\u003eComposition of different types of resin cement\u003c/p\u003e \u003c/div\u003e \u003c/caption\u003e \u003ccolgroup cols=\"5\"\u003e \u003cdiv align=\"left\" class=\"colspec\" colname=\"c1\" colnum=\"1\"\u003e\u003c/div\u003e \u003cdiv align=\"left\" class=\"colspec\" colname=\"c2\" colnum=\"2\"\u003e\u003c/div\u003e \u003cdiv align=\"left\" class=\"colspec\" colname=\"c3\" colnum=\"3\"\u003e\u003c/div\u003e \u003cdiv align=\"left\" class=\"colspec\" colname=\"c4\" colnum=\"4\"\u003e\u003c/div\u003e \u003cdiv align=\"left\" class=\"colspec\" colname=\"c5\" colnum=\"5\"\u003e\u003c/div\u003e \u003cthead\u003e \u003ctr\u003e \u003cth align=\"left\" colname=\"c1\"\u003e \u003cp\u003eResin cement\u003c/p\u003e \u003c/th\u003e \u003cth align=\"left\" colname=\"c2\"\u003e \u003cp\u003eLot No\u003c/p\u003e \u003c/th\u003e \u003cth align=\"left\" colname=\"c3\"\u003e \u003cp\u003eCement Type\u003c/p\u003e \u003c/th\u003e \u003cth align=\"left\" colname=\"c4\"\u003e \u003cp\u003eContents\u003c/p\u003e \u003c/th\u003e \u003cth align=\"left\" colname=\"c5\"\u003e \u003cp\u003eManufacturer\u003c/p\u003e \u003c/th\u003e \u003c/tr\u003e \u003c/thead\u003e \u003ctbody\u003e \u003ctr\u003e \u003ctd align=\"left\" colname=\"c1\"\u003e \u003cp\u003e\u003cb\u003eRelyX Ultimate\u003c/b\u003e\u003c/p\u003e \u003c/td\u003e \u003ctd align=\"left\" colname=\"c2\"\u003e \u003cp\u003e711943\u003c/p\u003e \u003c/td\u003e \u003ctd align=\"left\" colname=\"c3\"\u003e \u003cp\u003eUniversal adhesive cement that can be cured both chemically and with light.\u003c/p\u003e \u003c/td\u003e \u003ctd align=\"left\" colname=\"c4\"\u003e \u003cp\u003eMethacrylate monomers, silanized fillers, initiators, stabilizers, Dual-cure activators\u003c/p\u003e \u003c/td\u003e \u003ctd align=\"left\" colname=\"c5\"\u003e \u003cp\u003e3M ESPE GmbH dental Products Neuss, Almanya\u003c/p\u003e \u003c/td\u003e \u003c/tr\u003e \u003ctr\u003e \u003ctd align=\"left\" colname=\"c1\"\u003e \u003cp\u003e\u003cb\u003eRely X U200\u003c/b\u003e\u003c/p\u003e \u003c/td\u003e \u003ctd align=\"left\" colname=\"c2\"\u003e \u003cp\u003e6716146\u003c/p\u003e \u003c/td\u003e \u003ctd align=\"left\" colname=\"c3\"\u003e \u003cp\u003eSelf-adhesive resin cement\u003c/p\u003e \u003c/td\u003e \u003ctd align=\"left\" colname=\"c4\"\u003e \u003cp\u003eMatrix: hydroxyethylmethacrylate (HEMA), Bis-GMA Fillers: fluoro alumino silicate glass, zirconium silica\u003c/p\u003e \u003c/td\u003e \u003ctd align=\"left\" colname=\"c5\"\u003e \u003cp\u003e3M ESPE GmbH dental Products Neuss, Germany\u003c/p\u003e \u003c/td\u003e \u003c/tr\u003e \u003c/tbody\u003e \u003c/colgroup\u003e \u003c/table\u003e\u003c/div\u003e \u003c/p\u003e \u003c/div\u003e \u003c/div\u003e \u003cdiv id=\"Sec11\" class=\"Section2\"\u003e \u003ch2\u003eShear Bond Strength (SBS) Measurement\u003c/h2\u003e \u003cp\u003eThe Shear Test was conducted using the Shear Testing Machine (MTS Mini-ics, model 858, MTS Corporation, USA). The test involved applying a loading force of 0-400 N at a crosshead speed of 1mm/min. The bond strength was determined by recording the value at the point of failure. The results were then converted from Newton to mPa for statistical analysis. To determine the type of failure, fractured specimens were examined under a stereomicroscope (Olympus SZ51, Edmund Optics\u0026reg;, Inc., Barrington, USA) at \u0026times;32 magnification. Three types of failure were defined as follows:\u003c/p\u003e \u003cp\u003eAdhesive failure: This occurs when the resin cement completely separates from the composite surface.\u003c/p\u003e \u003cp\u003eCohesive failure: This happens when the resin cement fractures completely.\u003c/p\u003e \u003cp\u003eMixed failure: This is observed when both adhesive and cohesive failures are present simultaneously.\u003c/p\u003e \u003cp\u003eThese observations were made to understand the nature of failure and assess the performance of the resin cement used in the study.\u003c/p\u003e \u003c/div\u003e \u003cdiv id=\"Sec12\" class=\"Section2\"\u003e \u003ch2\u003eSEM(Scanning Electron Microscopy) Examination\u003c/h2\u003e \u003cp\u003eSome randomly selected specimens were sputter-coated with gold/palladium and examined with a SEM (Zeis EVO LS 10) (\u0026times;1000 and x3000).\u003c/p\u003e \u003c/div\u003e \u003cdiv id=\"Sec13\" class=\"Section2\"\u003e \u003ch2\u003eStatistical Analysis\u003c/h2\u003e \u003cp\u003eThe statistical analysis was conducted using SPSS version 24 software (IBM Corp. Armonk, NY, USA). The normality of the data was checked by the ShapiroWilk's test, comparisons of two independent groups that did not show normal distribution were analyzed with Mann-Whitney U test. Chi-square analysis was calculated for double-triple group comparisons. The level of significance was set to p\u0026thinsp;\u0026lt;\u0026thinsp;0.05.\u003c/p\u003e \u003c/div\u003e \u003cdiv id=\"Sec14\" class=\"Section2\"\u003e \u003ch2\u003eData availability\u003c/h2\u003e \u003cp\u003eThe datasets analysed during the current study are available from the corresponding author on reasonable request.\u003c/p\u003e \u003c/div\u003e"},{"header":"Results","content":"\u003cp\u003eThe Mann-Whitney U Test revealed significant differences between the dentin and microhybrid composite groups, as shown in Table 4. The mean shear bond strength value on the dentin surface was measured to be 5.6\u0026plusmn;2.9 MPa, while on the composite surface it was 9.3\u0026plusmn;3.5 MPa (p\u0026lt;0.001).\u003c/p\u003e\n\u003cp\u003eThese findings indicate that there is a statistically significant difference in the bond strength between the dentin and microhybrid composite groups. The composite surface exhibited a higher mean shear bond strength compared to the dentin surface. \u0026nbsp;\u003c/p\u003e\n\u003ctable border=\"1\" cellspacing=\"0\" cellpadding=\"0\"\u003e\n \u003ctbody\u003e\n \u003ctr\u003e\n \u003ctd width=\"17.43970315398887%\" valign=\"top\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"14.100185528756958%\" valign=\"top\"\u003e\n \u003cp\u003e\u003cstrong\u003eMinimum\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"15.769944341372913%\" valign=\"top\"\u003e\n \u003cp\u003e\u003cstrong\u003eMaximum\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"14.100185528756958%\" valign=\"top\"\u003e\n \u003cp\u003e\u003cstrong\u003eMean\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"14.100185528756958%\" valign=\"top\"\u003e\n \u003cp\u003e\u003cstrong\u003eStd. Dev\u003c/strong\u003e.\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"12.244897959183673%\" valign=\"top\"\u003e\n \u003cp\u003e\u003cstrong\u003eMedian\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"12.244897959183673%\" valign=\"top\"\u003e\n \u003cp\u003e\u003cstrong\u003eP Value\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd width=\"17.43970315398887%\" valign=\"top\"\u003e\n \u003cp\u003e\u003cstrong\u003eDentine\u003c/strong\u003e\u003c/p\u003e\n \u003cp\u003e\u003cstrong\u003eSurface\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"14.100185528756958%\" valign=\"top\"\u003e\n \u003cp\u003e0,85\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"15.769944341372913%\" valign=\"top\"\u003e\n \u003cp\u003e15,3\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"14.100185528756958%\" valign=\"top\"\u003e\n \u003cp\u003e5,6\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"14.100185528756958%\" valign=\"top\"\u003e\n \u003cp\u003e2,9\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"12.244897959183673%\" valign=\"top\"\u003e\n \u003cp\u003e5,3\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"12.244897959183673%\" valign=\"top\"\u003e\n \u003cp\u003e0,001**\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd width=\"17.43970315398887%\" valign=\"top\"\u003e\n \u003cp\u003e\u003cstrong\u003e3M Z250 \u0026nbsp; \u0026nbsp; \u0026nbsp; \u0026nbsp; \u0026nbsp; \u0026nbsp; \u0026nbsp; Micro-hybrid Composite\u003c/strong\u003e\u003c/p\u003e\n \u003cp\u003e\u003cstrong\u003eSurface\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"14.100185528756958%\" valign=\"top\"\u003e\n \u003cp\u003e2,15\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"15.769944341372913%\" valign=\"top\"\u003e\n \u003cp\u003e19,0\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"14.100185528756958%\" valign=\"top\"\u003e\n \u003cp\u003e9,3\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"14.100185528756958%\" valign=\"top\"\u003e\n \u003cp\u003e3,5\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"12.244897959183673%\" valign=\"top\"\u003e\n \u003cp\u003e9,01\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"12.244897959183673%\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003c/tbody\u003e\n\u003c/table\u003e\n\u003cp\u003eTable 4. Statistical Comparison of Shear Test Results on different surfaces (MPa)\u0026nbsp;\u003c/p\u003e\n\u003cp\u003eThe shear bond strengths of indirect composites luted on the dentin surface group with RX-ULT were respectively, CER\u0026gt;TES\u0026gt;GRA\u0026gt;LAVA. Other results were, TES\u0026gt;CER\u0026gt;GRA\u0026gt;LAVA luted with RX-U200 on dentin group and also the same for all other composite surface groups. LAVA showed significantly lower bond strength values for each group and the lowest value for LAVA luted on dentin surface with RX-U200 was 3.02\u0026plusmn;1.34 MPa (p\u0026lt;0.001). TES showed the highest bond strength at composite surface luted with RX-ULT with 13.17\u0026plusmn;2.45 MPa (Table 5.)\u0026nbsp;\u003c/p\u003e\n\u003ctable border=\"1\" cellspacing=\"0\" cellpadding=\"0\" width=\"604\"\u003e\n \u003ctbody\u003e\n \u003ctr\u003e\n \u003ctd width=\"33.88429752066116%\" valign=\"top\"\u003e\n \u003cp\u003e\u003cstrong\u003eShear Bond Strength Test Results(MPa)\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"12.892561983471074%\" valign=\"top\"\u003e\n \u003cp\u003e\u003cstrong\u003eMinimum\u0026nbsp;\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"14.049586776859504%\" valign=\"top\"\u003e\n \u003cp\u003e\u003cstrong\u003eMaximum\u0026nbsp;\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"10.909090909090908%\" valign=\"top\"\u003e\n \u003cp\u003e\u003cstrong\u003eMean\u0026nbsp;\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"12.561983471074381%\" valign=\"top\"\u003e\n \u003cp\u003e\u003cstrong\u003eStd. Dev.\u003c/strong\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"15.702479338842975%\" valign=\"top\"\u003e\n \u003cp\u003e\u003cstrong\u003eMedian\u0026nbsp;\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd width=\"33.88429752066116%\" valign=\"top\"\u003e\n \u003cp\u003eDentine-Tescera RX-U200\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"12.892561983471074%\" valign=\"top\"\u003e\n \u003cp\u003e1,88\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"14.049586776859504%\" valign=\"top\"\u003e\n \u003cp\u003e7,47\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"10.909090909090908%\" valign=\"top\"\u003e\n \u003cp\u003e4,81\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"12.561983471074381%\" valign=\"top\"\u003e\n \u003cp\u003e1,63\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"15.702479338842975%\" valign=\"top\"\u003e\n \u003cp\u003e5,35\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd width=\"33.88429752066116%\" valign=\"top\"\u003e\n \u003cp\u003eDentine-Tescera RX-ULT\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"12.892561983471074%\" valign=\"top\"\u003e\n \u003cp\u003e1,57\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"14.049586776859504%\" valign=\"top\"\u003e\n \u003cp\u003e15,28\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"10.909090909090908%\" valign=\"top\"\u003e\n \u003cp\u003e8,05\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"12.561983471074381%\" valign=\"top\"\u003e\n \u003cp\u003e3,68\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"15.702479338842975%\" valign=\"top\"\u003e\n \u003cp\u003e8,05\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd width=\"33.88429752066116%\" valign=\"top\"\u003e\n \u003cp\u003eDentine-Gradia RX-U200\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"12.892561983471074%\" valign=\"top\"\u003e\n \u003cp\u003e1,3\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"14.049586776859504%\" valign=\"top\"\u003e\n \u003cp\u003e5,79\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"10.909090909090908%\" valign=\"top\"\u003e\n \u003cp\u003e3,62\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"12.561983471074381%\" valign=\"top\"\u003e\n \u003cp\u003e1,23\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"15.702479338842975%\" valign=\"top\"\u003e\n \u003cp\u003e4,07\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd width=\"33.88429752066116%\" valign=\"top\"\u003e\n \u003cp\u003eDentine-Gradia RX-ULT\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"12.892561983471074%\" valign=\"top\"\u003e\n \u003cp\u003e3,66\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"14.049586776859504%\" valign=\"top\"\u003e\n \u003cp\u003e12,39\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"10.909090909090908%\" valign=\"top\"\u003e\n \u003cp\u003e6,98\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"12.561983471074381%\" valign=\"top\"\u003e\n \u003cp\u003e2,33\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"15.702479338842975%\" valign=\"top\"\u003e\n \u003cp\u003e6,77\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd width=\"33.88429752066116%\" valign=\"top\"\u003e\n \u003cp\u003eDentine-Lava RX-U200\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"12.892561983471074%\" valign=\"top\"\u003e\n \u003cp\u003e0,85\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"14.049586776859504%\" valign=\"top\"\u003e\n \u003cp\u003e4,35\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"10.909090909090908%\" valign=\"top\"\u003e\n \u003cp\u003e3,02\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"12.561983471074381%\" valign=\"top\"\u003e\n \u003cp\u003e1,34\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"15.702479338842975%\" valign=\"top\"\u003e\n \u003cp\u003e3,51\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd width=\"33.88429752066116%\" valign=\"top\"\u003e\n \u003cp\u003eDentine-Lava RX-ULT\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"12.892561983471074%\" valign=\"top\"\u003e\n \u003cp\u003e3,19\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"14.049586776859504%\" valign=\"top\"\u003e\n \u003cp\u003e13,99\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"10.909090909090908%\" valign=\"top\"\u003e\n \u003cp\u003e5,69\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"12.561983471074381%\" valign=\"top\"\u003e\n \u003cp\u003e2,85\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"15.702479338842975%\" valign=\"top\"\u003e\n \u003cp\u003e5,09\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd width=\"33.88429752066116%\" valign=\"top\"\u003e\n \u003cp\u003eDentine-Ceramage RX-U200\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"12.892561983471074%\" valign=\"top\"\u003e\n \u003cp\u003e2,16\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"14.049586776859504%\" valign=\"top\"\u003e\n \u003cp\u003e6,34\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"10.909090909090908%\" valign=\"top\"\u003e\n \u003cp\u003e3,3\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"12.561983471074381%\" valign=\"top\"\u003e\n \u003cp\u003e1,35\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"15.702479338842975%\" valign=\"top\"\u003e\n \u003cp\u003e2,98\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd width=\"33.88429752066116%\" valign=\"top\"\u003e\n \u003cp\u003eDentine-Ceramage RX-ULT\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"12.892561983471074%\" valign=\"top\"\u003e\n \u003cp\u003e5,35\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"14.049586776859504%\" valign=\"top\"\u003e\n \u003cp\u003e12,45\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"10.909090909090908%\" valign=\"top\"\u003e\n \u003cp\u003e8,63\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"12.561983471074381%\" valign=\"top\"\u003e\n \u003cp\u003e2,13\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"15.702479338842975%\" valign=\"top\"\u003e\n \u003cp\u003e8,12\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd width=\"33.88429752066116%\" valign=\"top\"\u003e\n \u003cp\u003eComposite-Tescera RX-U200\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"12.892561983471074%\" valign=\"top\"\u003e\n \u003cp\u003e10,04\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"14.049586776859504%\" valign=\"top\"\u003e\n \u003cp\u003e15,74\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"10.909090909090908%\" valign=\"top\"\u003e\n \u003cp\u003e12,56\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"12.561983471074381%\" valign=\"top\"\u003e\n \u003cp\u003e1,84\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"15.702479338842975%\" valign=\"top\"\u003e\n \u003cp\u003e12,15\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd width=\"33.88429752066116%\" valign=\"top\"\u003e\n \u003cp\u003eComposite-Tescera RX-ULT\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"12.892561983471074%\" valign=\"top\"\u003e\n \u003cp\u003e9,52\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"14.049586776859504%\" valign=\"top\"\u003e\n \u003cp\u003e19,03\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"10.909090909090908%\" valign=\"top\"\u003e\n \u003cp\u003e13,17\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"12.561983471074381%\" valign=\"top\"\u003e\n \u003cp\u003e2,45\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"15.702479338842975%\" valign=\"top\"\u003e\n \u003cp\u003e12,93\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd width=\"33.88429752066116%\" valign=\"top\"\u003e\n \u003cp\u003eComposite-Gradia RX-U200\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"12.892561983471074%\" valign=\"top\"\u003e\n \u003cp\u003e6,12\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"14.049586776859504%\" valign=\"top\"\u003e\n \u003cp\u003e10,9\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"10.909090909090908%\" valign=\"top\"\u003e\n \u003cp\u003e8,21\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"12.561983471074381%\" valign=\"top\"\u003e\n \u003cp\u003e1,37\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"15.702479338842975%\" valign=\"top\"\u003e\n \u003cp\u003e7,85\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd width=\"33.88429752066116%\" valign=\"top\"\u003e\n \u003cp\u003eComposite-Gradia RX-ULT\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"12.892561983471074%\" valign=\"top\"\u003e\n \u003cp\u003e5,66\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"14.049586776859504%\" valign=\"top\"\u003e\n \u003cp\u003e11,74\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"10.909090909090908%\" valign=\"top\"\u003e\n \u003cp\u003e8,63\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"12.561983471074381%\" valign=\"top\"\u003e\n \u003cp\u003e1,93\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"15.702479338842975%\" valign=\"top\"\u003e\n \u003cp\u003e8,94\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd width=\"33.88429752066116%\" valign=\"top\"\u003e\n \u003cp\u003eComposite-Lava RX-U200\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"12.892561983471074%\" valign=\"top\"\u003e\n \u003cp\u003e2,15\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"14.049586776859504%\" valign=\"top\"\u003e\n \u003cp\u003e7,2\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"10.909090909090908%\" valign=\"top\"\u003e\n \u003cp\u003e4,67\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"12.561983471074381%\" valign=\"top\"\u003e\n \u003cp\u003e1,4\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"15.702479338842975%\" valign=\"top\"\u003e\n \u003cp\u003e4,68\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd width=\"33.88429752066116%\" valign=\"top\"\u003e\n \u003cp\u003eComposite-Lava RX-ULT\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"12.892561983471074%\" valign=\"top\"\u003e\n \u003cp\u003e3,03\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"14.049586776859504%\" valign=\"top\"\u003e\n \u003cp\u003e7,76\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"10.909090909090908%\" valign=\"top\"\u003e\n \u003cp\u003e5,47\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"12.561983471074381%\" valign=\"top\"\u003e\n \u003cp\u003e1,59\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"15.702479338842975%\" valign=\"top\"\u003e\n \u003cp\u003e5,44\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd width=\"33.88429752066116%\" valign=\"top\"\u003e\n \u003cp\u003eComposite-Ceramage RX-U200\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"12.892561983471074%\" valign=\"top\"\u003e\n \u003cp\u003e5,43\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"14.049586776859504%\" valign=\"top\"\u003e\n \u003cp\u003e13,44\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"10.909090909090908%\" valign=\"top\"\u003e\n \u003cp\u003e9,71\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"12.561983471074381%\" valign=\"top\"\u003e\n \u003cp\u003e2,97\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"15.702479338842975%\" valign=\"top\"\u003e\n \u003cp\u003e9,66\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd width=\"33.88429752066116%\" valign=\"top\"\u003e\n \u003cp\u003eComposite-Ceramage RX-ULT\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"12.892561983471074%\" valign=\"top\"\u003e\n \u003cp\u003e8,01\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"14.049586776859504%\" valign=\"top\"\u003e\n \u003cp\u003e14,85\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"10.909090909090908%\" valign=\"top\"\u003e\n \u003cp\u003e10,88\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"12.561983471074381%\" valign=\"top\"\u003e\n \u003cp\u003e2,12\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"15.702479338842975%\" valign=\"top\"\u003e\n \u003cp\u003e10,45\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003c/tbody\u003e\n\u003c/table\u003e\n\u003cp\u003eTable 5. Shear bond strengths of indirect composites (MPa)\u0026nbsp;\u003c/p\u003e\n\u003cp\u003eWhen we compare the groups according to used resin cements, the results varied depending on the luted surface. There was a highly significant difference between RX-ULT and RX-U200 groups luted on dentin surface.(TableX) Indirect composite groups luted with RX-ULT showed higher bond strength than groups luted with RX-U200 on dentin surfaces(p\u0026lt;0.005). Otherwise, there was no significant difference between bond strength of indirect composites luted on composite surfaces with RX-ULT and RX-U200(p\u0026gt;0.05) (Table 6.) \u0026nbsp;\u003c/p\u003e\n\u003ctable border=\"1\" cellspacing=\"0\" cellpadding=\"0\"\u003e\n \u003ctbody\u003e\n \u003ctr\u003e\n \u003ctd width=\"79.15831663326654%\" valign=\"top\"\u003e\n \u003cp\u003e\u003cstrong\u003eComparision of Adhesive Cement Type\u0026rsquo;s Stress Values\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"20.841683366733466%\" valign=\"top\"\u003e\n \u003cp\u003e\u003cstrong\u003eStress P Value\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd width=\"79.15831663326654%\" valign=\"top\"\u003e\n \u003cp\u003eDentine - Tescera ( RX-U200-RX-ULT)\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"20.841683366733466%\" valign=\"top\"\u003e\n \u003cp\u003e0,005*\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd width=\"79.15831663326654%\" valign=\"top\"\u003e\n \u003cp\u003eDentine - Ceramage ( RX-U200-RX-ULT)\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"20.841683366733466%\" valign=\"top\"\u003e\n \u003cp\u003e0,001**\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd width=\"79.15831663326654%\" valign=\"top\"\u003e\n \u003cp\u003eDentine - Gradia ( RX-U200-RX-ULT)\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"20.841683366733466%\" valign=\"top\"\u003e\n \u003cp\u003e0,001**\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd width=\"79.15831663326654%\" valign=\"top\"\u003e\n \u003cp\u003eDentine - Lava ( RX-U200-RX-ULT)\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"20.841683366733466%\" valign=\"top\"\u003e\n \u003cp\u003e0,003*\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd width=\"79.15831663326654%\" valign=\"top\"\u003e\n \u003cp\u003eComposite - Tescera ( RX-U200 - RX-ULT)\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"20.841683366733466%\" valign=\"top\"\u003e\n \u003cp\u003e0,650\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd width=\"79.15831663326654%\" valign=\"top\"\u003e\n \u003cp\u003eComposite - Ceramage ( RX-U200-RX-ULT)\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"20.841683366733466%\" valign=\"top\"\u003e\n \u003cp\u003e0,443\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd width=\"79.15831663326654%\" valign=\"top\"\u003e\n \u003cp\u003eComposite - Gradia ( RX-U200-RX-ULT)\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"20.841683366733466%\" valign=\"top\"\u003e\n \u003cp\u003e0,541\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd width=\"79.15831663326654%\" valign=\"top\"\u003e\n \u003cp\u003eComposite - Lava ( RX-U200-RX-ULT)\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"20.841683366733466%\" valign=\"top\"\u003e\n \u003cp\u003e0,266\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003c/tbody\u003e\n\u003c/table\u003e\n\u003cp\u003eTable 6. Statistical Comparison of Different Types of Adhesive Cement Application on dentine and composite groups.\u0026nbsp;\u003c/p\u003e\n\u003cp\u003eTable 7 shows the failure mode distributions of the experimental groups. Adhesive failures were more common in dentin groups, whereas cohesive failures were more common in composite groups. \u0026nbsp;The failure modes for dentin group were 20,6% cohesive failure occured between the dentin and the adhesive resin cement cement, 66,7% adhesive failure occured inside the resin cement and 33.3% mixed failure. For microhybride composite group; 33,3% adhesive failure, 79,4% cohesive failure and 50,2% mixed failure were observed.\u0026nbsp;\u003c/p\u003e\n\u003ctable border=\"1\" cellspacing=\"0\" cellpadding=\"0\"\u003e\n \u003ctbody\u003e\n \u003ctr\u003e\n \u003ctd width=\"48.739495798319325%\" colspan=\"5\" valign=\"top\"\u003e\n \u003cp\u003e\u003cstrong\u003eDentine\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"51.260504201680675%\" colspan=\"4\" valign=\"top\"\u003e\n \u003cp\u003e\u003cstrong\u003eComposite(Z-250 Microhybrid)\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd width=\"18.624161073825505%\" valign=\"top\"\u003e\n \u003cp\u003e\u003cstrong\u003eFracture\u003c/strong\u003e\u003c/p\u003e\n \u003cp\u003e\u003cstrong\u003eType\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"12.583892617449665%\" valign=\"top\"\u003e\n \u003cp\u003e\u0026nbsp;Count\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"17.61744966442953%\" colspan=\"3\" valign=\"top\"\u003e\n \u003cp\u003e%\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"14.261744966442953%\" valign=\"top\"\u003e\n \u003cp\u003eCount\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"14.261744966442953%\" valign=\"top\"\u003e\n \u003cp\u003e%\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"12.751677852348994%\" valign=\"top\"\u003e\n \u003cp\u003eTotal\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"9.899328859060402%\" valign=\"top\"\u003e\n \u003cp\u003ep\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd width=\"18.624161073825505%\" valign=\"top\"\u003e\n \u003cp\u003e\u003cstrong\u003eAdhesive\u0026nbsp;\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"12.751677852348994%\" colspan=\"2\" valign=\"top\"\u003e\n \u003cp\u003e71\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"17.449664429530202%\" colspan=\"2\" valign=\"top\"\u003e\n \u003cp\u003e66%\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"14.261744966442953%\" valign=\"top\"\u003e\n \u003cp\u003e35\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"14.261744966442953%\" valign=\"top\"\u003e\n \u003cp\u003e33%\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"12.751677852348994%\" valign=\"top\"\u003e\n \u003cp\u003e106\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"9.899328859060402%\" valign=\"top\"\u003e\n \u003cp\u003e\u0026nbsp; 0,001\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd width=\"18.624161073825505%\" valign=\"top\"\u003e\n \u003cp\u003e\u003cstrong\u003eCohesive\u0026nbsp;\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"12.751677852348994%\" colspan=\"2\" valign=\"top\"\u003e\n \u003cp\u003e6\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"17.449664429530202%\" colspan=\"2\" valign=\"top\"\u003e\n \u003cp\u003e20%\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"14.261744966442953%\" valign=\"top\"\u003e\n \u003cp\u003e25\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"14.261744966442953%\" valign=\"top\"\u003e\n \u003cp\u003e80%\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"12.751677852348994%\" valign=\"top\"\u003e\n \u003cp\u003e31\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"9.899328859060402%\" valign=\"top\"\u003e\n \u003cp\u003e\u0026nbsp; 0,001\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd width=\"18.624161073825505%\" valign=\"top\"\u003e\n \u003cp\u003e\u003cstrong\u003eMix\u0026nbsp;\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"12.751677852348994%\" colspan=\"2\" valign=\"top\"\u003e\n \u003cp\u003e19\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"17.449664429530202%\" colspan=\"2\" valign=\"top\"\u003e\n \u003cp\u003e35%\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"14.261744966442953%\" valign=\"top\"\u003e\n \u003cp\u003e36\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"14.261744966442953%\" valign=\"top\"\u003e\n \u003cp\u003e65%\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"12.751677852348994%\" valign=\"top\"\u003e\n \u003cp\u003e55\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"9.899328859060402%\" valign=\"top\"\u003e\n \u003cp\u003e\u0026nbsp; 0,001\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd width=\"18.624161073825505%\" valign=\"top\"\u003e\n \u003cp\u003eTotal \u0026nbsp; \u0026nbsp; \u0026nbsp; \u0026nbsp; \u0026nbsp; \u0026nbsp; \u0026nbsp; \u0026nbsp; \u0026nbsp; \u0026nbsp; \u0026nbsp; \u0026nbsp; \u0026nbsp; \u0026nbsp;\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"12.751677852348994%\" colspan=\"3\" valign=\"top\"\u003e\n \u003cp\u003e96 \u0026nbsp; \u0026nbsp; \u0026nbsp;\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"17.449664429530202%\" valign=\"top\"\u003e\n \u003cp\u003e50%\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"14.261744966442953%\" valign=\"top\"\u003e\n \u003cp\u003e96\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"14.261744966442953%\" valign=\"top\"\u003e\n \u003cp\u003e50%\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"12.751677852348994%\" valign=\"top\"\u003e\n \u003cp\u003e\u0026nbsp;192\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd width=\"9.899328859060402%\" valign=\"top\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003c/tbody\u003e\n\u003c/table\u003e\n\u003cp\u003eTable 7. Statistical Evaluation of Fracture Types\u0026nbsp;\u003c/p\u003e\n\u003cp\u003eRepresentative SEM images of the resin cement/ dentin interface of GRA luted on dentin surface with RX-U200 are shown in Figure 1, CER luted on dentin surface with RX-U200 are shown in Figure 2. The images of resin cement/Z250 Microhybrid composite interface of TES luted on composite surface with RX-ULT are shown in Figure 3 and LAVA luted on composite surface with RX-U200 in Figure 4. The adhesive fracture and remnants of bonding agent in dentin tubules(hybrid layer) can be seen in Figure 2.\u0026nbsp;\u003c/p\u003e"},{"header":"Discussion","content":"\u003cp\u003eThe first null hypothesis, which stated that the shear bond strength of traditional and CAD/CAM indirect composite materials would be similar, was rejected. The mean bond strength of Lava\u0026trade; Ultimate CAD/CAM Block (3M ESPE) was found to be the lowest on both dentin and composite surfaces.\u003c/p\u003e \u003cp\u003eSignificant research endeavors have been undertaken in the evolution of composite resins within the realm of CAD/CAM systems. These materials have found utility in the fabrication of both provisional restorations and enduring fixed prosthetic solutions. Capitalizing on the progressive advancements in technology, novel and more resilient resin-based restorative materials, adaptable for utilization within computerized frameworks, have emerged. Examples of such materials encompass Lava Ultimate (3M ESPE), Cerasmart (GC), Enamic (Vita), and Tetric CAD (Ivoclar Vivadent), each tailored to harness the benefits of evolving technology\u003csup\u003e\u003cspan citationid=\"CR21\" class=\"CitationRef\"\u003e21\u003c/span\u003e,\u003cspan citationid=\"CR22\" class=\"CitationRef\"\u003e22\u003c/span\u003e\u003c/sup\u003e. CAD-CAM composite materials, characterized by a resin matrix interspersed with ceramic particles, can be categorized into two primary groups: resin nano-ceramics and hybrid ceramics. This classification hinges upon the relative proportions of ceramics and composites within their foundational components. Pioneering the realm of resin nano-ceramics is Lava Ultimate, comprised of a composition including 80% nanoceramic composite complexes, BisGMA, TEGDMA, as well as silica and zircon filler particles, as reported in prior studies \u003csup\u003e\u003cspan citationid=\"CR21\" class=\"CitationRef\"\u003e21\u003c/span\u003e,\u003cspan citationid=\"CR22\" class=\"CitationRef\"\u003e22\u003c/span\u003e\u003c/sup\u003e.\u003c/p\u003e \u003cp\u003eAmong the indirect composite materials used, Gradia Indirect has 75% microglass and ceramic fillers, Ceramage has 73% microglass and ceramic fillers, and Tescera ATL has 85% microglass and ceramic fillers. On the other hand, Lava Ultimate consists of 80% nanoceramic composite complexes, silica, and zircon, as well as ceramic filler particles \u003csup\u003e\u003cspan citationid=\"CR23\" class=\"CitationRef\"\u003e23\u003c/span\u003e\u003c/sup\u003e. The disparity in bond strength observed in our study could potentially stem from the variances in the compositions of conventional and CAD/CAM indirect composite materials. Notably, the incorporation of Glassfrit components in Tescera ATL might contribute to its heightened resilience compared to the other composite groups.\u003csup\u003e\u003cspan citationid=\"CR23\" class=\"CitationRef\"\u003e23\u003c/span\u003e\u003c/sup\u003e.\u003c/p\u003e \u003cp\u003eAnother contributing factor could be the diverse polymerization techniques employed in the composite systems. A multitude of previously documented investigations have underscored that a heightened level of monomer conversion enhances both the physical and chemical attributes of the composite.\u003csup\u003e\u003cspan citationid=\"CR24\" class=\"CitationRef\"\u003e24\u003c/span\u003e,\u003cspan citationid=\"CR25\" class=\"CitationRef\"\u003e25\u003c/span\u003e\u003c/sup\u003e. In this study, Gradia indirect composite achieves polymerization solely through light activation, while Ceramage indirect composite undergoes a dual process of polymerization utilizing both heat and light within an oven. Conversely, Lava Ultimate CAD-CAM blocks undergo milling without necessitating an additional polymerization stage. The notable robust bonding values observed in the Tescera ATL group can be ascribed to its unique polymerization method, which involves a pressure oven supplemented with an oxygen scavenger capsule, alongside heat and light exposure throughout the polymerization cycle. As a consequence, this process yields a substantial degree of monomer conversion.\u003c/p\u003e \u003cp\u003eSimilar to our investigation, Ozakar-Ilda conducted an in vivo study assessing the clinical efficacy of two types of indirect composite inlays in comparison to direct composite restorations over a span of three years. The outcomes of this study revealed a success rate of 93% for Tescera ATL (BISCO, Inc Schaumburg) system indirect inlays, 86% for Brilliant Esthetic Line (Colt\u0026egrave;ne/Whaledent) indirect inlays, and 67% for Valux Plus (3M ESPE) direct composite fillings, based on the modified USPHS criteria.\u003csup\u003e\u003cspan citationid=\"CR26\" class=\"CitationRef\"\u003e26\u003c/span\u003e\u003c/sup\u003e. Similarly, \u0026Ccedil;etin et al. conducted a five-year evaluation of direct nanofilled and indirect composite resin restorations in posterior teeth, concluding that Tescera ATL received an Alpha score based on the modified USPHS criteria, indicative of excellent performance.\u003csup\u003e\u003cspan citationid=\"CR27\" class=\"CitationRef\"\u003e27\u003c/span\u003e,\u003cspan citationid=\"CR28\" class=\"CitationRef\"\u003e28\u003c/span\u003e\u003c/sup\u003e.\u003c/p\u003e \u003cp\u003eTwo distinct adhesive cement materials were employed within this investigation. The initial adhesive cement, Rely X U200 represents a self-adhesive cement. Conversely, the second material, Rely X Ultimate constitutes a dual-cure cement capable of undergoing both light and chemical curing processes, utilized in tandem with a total etch adhesive system.\u003c/p\u003e \u003cp\u003eThe secondary hypothesis, which posited similarity in shear bond strength between dual-cure and self-cure adhesive cements, has been partially refuted. Specifically, in the context of dentin surfaces, the indirect composite groups bonded with Rely X Ultimate exhibited superior bond strength in comparison to those connected with Rely X U200 (p\u0026thinsp;\u0026lt;\u0026thinsp;0.005). In contrast, no statistically significant discrepancy in bond strength emerged between the Rely X Ultimate and Rely X U200 adhesive systems for indirect composite groups bonded onto composite surfaces (p\u0026thinsp;\u0026gt;\u0026thinsp;0.05). In our obtained results, the shear strength assessments within the experimental group utilizing the total-etch bonding system revealed higher bond strengths for restorations affixed to both dentin and enamel surfaces compared to the self-adhesive system\u003csup\u003e\u003cspan citationid=\"CR29\" class=\"CitationRef\"\u003e29\u003c/span\u003e,\u003cspan citationid=\"CR30\" class=\"CitationRef\"\u003e30\u003c/span\u003e\u003c/sup\u003e. The diminished values observed within the groups employing the self-etch resin cement system can be attributed to the inability of self-adhesive resin cements to effectively eliminate the smear layer. Consequently, the formation of a substantial, deep, and robust hybrid layer is compromised. \u003csup\u003e\u003cspan citationid=\"CR31\" class=\"CitationRef\"\u003e31\u003c/span\u003e,\u003cspan citationid=\"CR32\" class=\"CitationRef\"\u003e32\u003c/span\u003e\u003c/sup\u003e.\u003c/p\u003e \u003cp\u003eKim et al. conducted an investigation into the impact of cementation methods on the tensile strength of self-adhesive resin cements when bonded to composite blocks. Within the study, CAD/CAM blocks were fabricated, with the initial group being cemented using RelyX Ultimate alongside the conventional Single Bonding agent. In the remaining groups, self-adhesive dual-cure cements, namely RelyX U-200 and G-CEM Cerasmart, were employed. The outcomes of the study revealed that the highest shear strength was observed in the cementation achieved using RelyX Ultimate in conjunction with the Single Bond Universal (3M Espe) bonding agent.\u003csup\u003e\u003cspan citationid=\"CR33\" class=\"CitationRef\"\u003e33\u003c/span\u003e\u003c/sup\u003e. Various investigations have indicated that conventional resin cement exhibits superiority over self-adhesive resin cement concerning aspects such as microleakage and biodegradation. \u003csup\u003e\u003cspan citationid=\"CR34\" class=\"CitationRef\"\u003e34\u003c/span\u003e\u003c/sup\u003e.\u003c/p\u003e \u003cp\u003eThe final null hypothesis, which postulated that the shear bond strength would be comparable between dentin and composite surfaces, is also refuted based on the outcomes of this study. The shear bond strength measurements on the composite surface surpassed those on dentin across all groups adhered to both dentin and the Z250 microhybrid composite surface using RelyX-U200 and Rely-X Ultimate (p\u0026thinsp;\u0026lt;\u0026thinsp;0.05). We speculate that the higher bond strength on the composite surface may be due to the formation of polymer-polymer linked bonding between the Z250, a universal resin composite material with a microhybrid structure, and the adhesive resin cement materials. Additionally, we believe that the limited presence of enamel on the surfaces, which are primarily composed of dentin tissue, may resin weak adhesion due to the insufficient formation of the hybrid layer in dentin. When the literature on this subject was examined, no similar study was found. We think that the results we have obtained will be a reference for future studies \u003csup\u003e\u003cspan citationid=\"CR30\" class=\"CitationRef\"\u003e30\u003c/span\u003e,\u003cspan citationid=\"CR35\" class=\"CitationRef\"\u003e35\u003c/span\u003e\u003c/sup\u003e.\u003c/p\u003e \u003cp\u003eIn the present study, our objective was to replicate the Deep Margin Elevation (DME) technique by cementing Z250 microhybrid composite and indirect resin restoration. The findings revealed that the cementation of indirect composite onto an elevated microhybrid composite margin does not lead to a reduction in shear bond strength (SBS); rather, it results in an increase. In their investigation of deep margin elevation, Theisen, Spreafico R., and M\u0026uuml;ller V. reported that the elevation of the margin did not have a negative impact on the adhesion quality between the restoration and the tooth structure. \u003csup\u003e\u003cspan additionalcitationids=\"CR37\" citationid=\"CR36\" class=\"CitationRef\"\u003e36\u003c/span\u003e\u0026ndash;\u003cspan citationid=\"CR38\" class=\"CitationRef\"\u003e38\u003c/span\u003e\u003c/sup\u003e. Based on the recent comprehensive review by Eggman et al., which encompasses 38 studies on Deep Margin Elevation, it is indicated that DME does not result in any adverse consequences for the fracture resistance of restored teeth. While there is conflicting evidence regarding the influence of DME on marginal quality, the majority of in vitro studies have reported no detrimental effects. \u003csup\u003e\u003cspan citationid=\"CR39\" class=\"CitationRef\"\u003e39\u003c/span\u003e\u003c/sup\u003e.\u003c/p\u003e \u003cp\u003eIn numerous studies, surface pretreatment techniques for the DME surface, such as grit blasting, diamond bur finishing, tribochemical silica coating, gentle air-borne particle abrasion with sodium bicarbonate, as well as the application of a silane coupling agent and/or adhesive or a combination of these methods, have been recommended to enhance bond strength. \u003csup\u003e\u003cspan additionalcitationids=\"CR41 CR42 CR43 CR44\" citationid=\"CR40\" class=\"CitationRef\"\u003e40\u003c/span\u003e\u0026ndash;\u003cspan citationid=\"CR45\" class=\"CitationRef\"\u003e45\u003c/span\u003e\u003c/sup\u003e. In this research, no surface pre-treatment procedures were administered to any specimen to maintain uniformity across all experimental groups. Future inquiries could be pursued to explore the influence of surface conditioning on the bonding strength between diverse surfaces and cement materials. This current investigation was conducted in vitro, and it's important to acknowledge that in vitro studies come with inherent limitations. Prior to the shear bond strength assessment, the specimens were stored in distilled water at 37\u0026deg;C\u0026thinsp;\u0026plusmn;\u0026thinsp;2\u0026deg;C for 24 hours (short-term). However, it's important to note that biodegradation is influenced by a combination of factors, including disintegration and dissolution in saliva, chemical and physical degradation, wear due to occlusal forces, erosion caused by acidic foods and beverages, and bacterial activity. \u003csup\u003e\u003cspan citationid=\"CR46\" class=\"CitationRef\"\u003e46\u003c/span\u003e\u003c/sup\u003e \u0026Oslash;ilo pointed out that the degradation of composite materials and bonding agents in the oral cavity involves a complex interaction process that cannot be fully replicated in vitro. Therefore, it's essential to acknowledge the limitations of simulating the oral environment in this in vitro study. \u003csup\u003e\u003cspan citationid=\"CR46\" class=\"CitationRef\"\u003e46\u003c/span\u003e\u003c/sup\u003e\u003c/p\u003e"},{"header":"Conclusion","content":"\u003cp\u003e1.Adhesive resin cement systems with acid etching and bonding application exhibited higher shear bond strength than self-adhesive cement systems.\u003c/p\u003e\n\u003cp\u003e2. Indirect restoration materials showed a much better SBS on the microhybrid composite than on the dentine surface. The Deep Margin Elevation(DME) process performed in very deep cavities not only eliminates the problems that may occur during the cementation of the indirect restoration, but also allows long-lasting restorations to be obtained with high bond strength.\u003c/p\u003e\n\u003cp\u003e3. Tescera ATL showed the highest SBS among the indirect composite groups.\u003c/p\u003e\n\u003cp\u003e4. Lava Ultimate showed the lowest SBS value among the indirect composite groups.\u003c/p\u003e\n\u003cp\u003e5. According to the fracture types examinations with stereomicroscope, it was observed that the most cohesive type fracture was observed in the Z250 microhybrid composite groups, while the adhesive type fracture occurred in the dentine groups.\u003c/p\u003e"},{"header":"Declarations","content":"\u003cp\u003e \u003ch2\u003eCompeting interests\u003c/h2\u003e \u003cp\u003eThe authors declare no competing interests.\u003c/p\u003e \u003c/p\u003e\u003ch2\u003eAuthor Contribution\u003c/h2\u003e\u003cp\u003eOEB,OY and EK wrote the main manuscript text. OE and EK prepared figures. BIG, OE, EK and OY were obtained special molds for fixing the samples in the shear testing device. OE, FY and SEB were recorded data by performing the shear bond test in the Laboratory of the Faculty of Mechanical Engineering. All authors have substantially revised the manuscript and done the final editing; all authors have read and agreed to the published version of the manuscript.\u003c/p\u003e\u003ch2\u003eAcknowledgements\u003c/h2\u003e \u003cp\u003eTo Dr. Oktay Yazıcıoglu for providing valuable supports and leading for the present research.\u003c/p\u003e\n\u003ch1\u003e\u003cstrong\u003eAdditional information\u003c/strong\u003e\u003c/h1\u003e\n\u003cp\u003e\u003cstrong\u003eCorrespondence\u003c/strong\u003e and requests for materials should be addressed to OEB.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eReprints and permissions information\u003c/strong\u003e is available at www.nature.com/reprints.\u0026nbsp;\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003ePublisher’s note\u003c/strong\u003e Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional afliations.\u003c/p\u003e"},{"header":"References","content":"\u003col\u003e\n\u003cli\u003eMount, G. 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In vitro evaluation of marginal and internal adaptation of class II CAD/CAM ceramic restorations with different resinous bases and interface treatments. \u003cem\u003eClin Oral Investig\u003c/em\u003e \u003cstrong\u003e19\u003c/strong\u003e, 2167-2177, doi:10.1007/s00784-015-1449-9 (2015).\u003c/li\u003e\n\u003cli\u003eZhang, H.\u003cem\u003e et al.\u003c/em\u003e Effect of proximal box elevation on fracture resistance and microleakage of premolars restored with ceramic endocrowns. \u003cem\u003ePLoS One\u003c/em\u003e \u003cstrong\u003e16\u003c/strong\u003e, e0252269, doi:10.1371/journal.pone.0252269 (2021).\u003c/li\u003e\n\u003cli\u003e\u0026Oslash;ilo, G. Biodegradation of Dental Composites/ Glass-Ionomer Cements. \u003cem\u003eAdvances in Dental Research\u003c/em\u003e \u003cstrong\u003e6\u003c/strong\u003e, 50-54, doi:10.1177/08959374920060011701 (1992).\u003c/li\u003e\n\u003c/ol\u003e"}],"fulltextSource":"","fullText":"","funders":[],"hasAdminPriorityOnWorkflow":false,"hasManuscriptDocX":true,"hasOptedInToPreprint":true,"hasPassedJournalQc":"","hasAnyPriority":false,"hideJournal":true,"highlight":"","institution":"","isAcceptedByJournal":false,"isAuthorSuppliedPdf":false,"isDeskRejected":"","isHiddenFromSearch":false,"isInQc":false,"isInWorkflow":false,"isPdf":false,"isPdfUpToDate":true,"isWithdrawnOrRetracted":false,"journal":{"display":true,"email":"
[email protected]","identity":"researchsquare","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":true,"externalIdentity":"","sideBox":"","snPcode":"","submissionUrl":"/submission","title":"Research Square","twitterHandle":"researchsquare","acdcEnabled":true,"dfaEnabled":false,"editorialSystem":"","reportingPortfolio":"","inReviewEnabled":false,"inReviewRevisionsEnabled":true},"keywords":"Indirect composite, micro-hybrid composite, shear bond strength","lastPublishedDoi":"10.21203/rs.3.rs-3821900/v1","lastPublishedDoiUrl":"https://doi.org/10.21203/rs.3.rs-3821900/v1","license":{"name":"CC BY 4.0","url":"https://creativecommons.org/licenses/by/4.0/"},"manuscriptAbstract":"\u003cp\u003eThis study aims to compare the shear bond strength of different indirect restorative materials bonded to the microhybrid composite and dentin surfaces. A total of 192 cylindrical specimens (3mm height, 3mm diameter) were prepared from GradiaPlus, GC(GRA); CeramageBody, Shofu(CER); TesceraATL, Bisco(TES); and Lava Ultimate, 3M Espe(LAV) materials. In addition, 48 newly extracted molars were embedded in acrylic resin 2 mm below the cementoenamel junction and sliced horizontally using a cutting device (IsoMet 1000; Buehler, USA) to form flat dentin surfaces. Using a specially customized 4x2mm disc-shaped mold, 48 disc-shaped composite surfaces were obtained with the Z250 Microhybrid composite (3M Espe, USA) material by layering technique. A total of 2 cylindrical indirect composite specimens were cemented to each disc-shaped composite and flat dentin surfaces. Samples obtained from indirect composite were divided into 16 groups in total, with two different subgroups luted with RelyX U200(RX-U200) self-adhesive cement (3M Espe, USA) and RelyX Ultimate(RX-ULT) clicker dual-cure cement (3M Espe, USA) to the dentin and microhybrid composite surfaces (n\u0026thinsp;=\u0026thinsp;12). Groups are respectively: 1)GRA\u0026thinsp;+\u0026thinsp;Dentin\u0026thinsp;+\u0026thinsp;RX-U200 2)TES\u0026thinsp;+\u0026thinsp;Dentin\u0026thinsp;+\u0026thinsp;RX-U200 3)CER\u0026thinsp;+\u0026thinsp;Dentin\u0026thinsp;+\u0026thinsp;RX-U200 4)LAVA\u0026thinsp;+\u0026thinsp;Dentin\u0026thinsp;+\u0026thinsp;RX-U200 5)GRA\u0026thinsp;+\u0026thinsp;Composite\u0026thinsp;+\u0026thinsp;RX-U200 6)TES\u0026thinsp;+\u0026thinsp;Composite\u0026thinsp;+\u0026thinsp;RX-U200 7)CER\u0026thinsp;+\u0026thinsp;Composite\u0026thinsp;+\u0026thinsp;RX-U200 8)LAVA\u0026thinsp;+\u0026thinsp;Composite\u0026thinsp;+\u0026thinsp;RX-U200 9)GRA\u0026thinsp;+\u0026thinsp;Dentin\u0026thinsp;+\u0026thinsp;RX-ULT 10)TES\u0026thinsp;+\u0026thinsp;Dentin\u0026thinsp;+\u0026thinsp;RX-ULT 11)CER\u0026thinsp;+\u0026thinsp;Dentin\u0026thinsp;+\u0026thinsp;RX-ULT 12)LAVA\u0026thinsp;+\u0026thinsp;Dentin\u0026thinsp;+\u0026thinsp;RX-ULT 13)GRA\u0026thinsp;+\u0026thinsp;Composite\u0026thinsp;+\u0026thinsp;RX-ULT 14)TES\u0026thinsp;+\u0026thinsp;Composite\u0026thinsp;+\u0026thinsp;RX-ULT 15)CER\u0026thinsp;+\u0026thinsp;Composite\u0026thinsp;+\u0026thinsp;RX-ULT 16)LAVA\u0026thinsp;+\u0026thinsp;Composite\u0026thinsp;+\u0026thinsp;RX-ULT (n\u0026thinsp;=\u0026thinsp;12). The Shear Test was carried out by applying 0-400 N loading and 1 mm/min force to each sample at Instron Universal Testing Machine. Light microscopy and SEM were used to examine the failure type. The results obtained in the study were evaluated by using ShapiroWilk's test, Mann-Whitney U test and Chi-Square test.(p\u0026thinsp;\u0026lt;\u0026thinsp;0.05) Significantly higher bonding values were obtained in the specimens bonded to the surface of Z250 microhybrid composite (3M ESPE, USA) compared to the specimens bonded to the dentin surface (p\u0026thinsp;\u0026lt;\u0026thinsp;0.001). When the shear strength of indirect restoration materials is compared; the highest value was measured in the CER\u0026thinsp;+\u0026thinsp;Composite\u0026thinsp;+\u0026thinsp;RX-ULT(Av:91.41Mpa) group, and the lowest value was measured in the LAVA\u0026thinsp;+\u0026thinsp;Dentin\u0026thinsp;+\u0026thinsp;RX-U200(Mean:35.96Mpa) group(p\u0026thinsp;\u0026lt;\u0026thinsp;0.001). When the bond strengths of the cement systems were compared, RX-ULT dual-cure cement showed higher bond strength values than RX-U200 self-adhesive cement on both dentin and Z250 Microhybrid composite surface (p\u0026thinsp;\u0026lt;\u0026thinsp;0.05).\u003c/p\u003e \u003cp\u003e \u003c/p\u003e","manuscriptTitle":"Comparison of Bond Strength of Different Indirect Composite Systems and CAD/CAM Composite Blocks between Dentin and Composite Surfaces: An in vitro study","msid":"","msnumber":"","nonDraftVersions":[{"code":1,"date":"2024-01-03 05:31:40","doi":"10.21203/rs.3.rs-3821900/v1","editorialEvents":[{"type":"communityComments","content":0}],"status":"published","journal":{"display":true,"email":"
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