The simultaneous expression of human chorionic gonadotropin and carcinoembryonic antigen in the female genital tract. Localization by immunocytochemistry

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Immunocytochemistry revealed that 0.5% of gynecologic tissue samples simultaneously expressed human chorionic gonadotropin and carcinoembryonic antigen, with ovarian and endometrial neoplasms showing the most varied marker expression.

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Abstract

Tissue from 180 gynecologic disorders were studied for the simultaneous expression of HCG and CEA, utilizing the immunoperoxidase technique. Of the total population, 0.5% expressed both antigens, 8.8% expressed only hCG, and 5.5% expressed only CEA; 85% expressed neither. The greatest variability of marker expression was among the ovarian and endometrial neoplasms.

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Condition tags

endometriosis

MeSH descriptors

Carcinoembryonic Antigen Chorionic Gonadotropin Genitalia, Female Genital Neoplasms, Female Adenocarcinoma Adenocarcinoma Carcinoembryonic Antigen Carcinoma, Squamous Cell Carcinoma, Squamous Cell Chorionic Gonadotropin Cystadenoma Cystadenoma Endometriosis Endometriosis Female Genitalia, Female Genital Neoplasms, Female Humans Immunoenzyme Techniques

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Source provenance

europepmc
last seen: 2026-08-30T09:23:35.175841+00:00
pubmed
last seen: 2026-05-13T22:10:10.897782+00:00
License: public-domain-us · commercial use OK · attribution required
Courtesy of the U.S. National Library of Medicine