[Women's Life Stages and Migraine]

The paper discusses how migraine prevalence and severity are particularly high in women aged 20–40 and argues that fluctuations in female hormones across life stages substantially influence migraine pathophysiology and management. It reviews hormonal contexts including the menstrual cycle, pregnancy and puerperium, menopause, and hormone therapy use, and highlights clinical considerations such as managing severe menstrual migraine, selecting options when migraine is complicated by endometriosis, and choosing medications during pregnancy and lactation. A stated limitation is that the abstract frames the discussion at an overview level rather than presenting new primary data or a specific study design. Relevance to endometriosis: the paper explicitly cites treatment considerations for migraines complicated by endometriosis, though its main focus is the relationship between women’s life stages, hormonal influences, and migraine.

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