A Unique Case of Wilkie Syndrome Reported in a Middle-Aged Female with Posterior Nutcracker Syndrome

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Abstract

Abstract Nutcracker and Wilkie syndromes are rarely encountered, often being diagnosed incidentally during imaging investigations for other conditions. In this paper, we present the case of a 36-year-old patient with quasi-permanent symptoms characterized by epigastralgia, loss of appetite, early satiety, left lumbar colic pain, and dysuria. The clinical examination revealed a supple abdomen, sensitivity to palpation in the epigastrium and hypogastrium, frequent urination, and severe protein-caloric malnutrition body mass index (BMI = 15 kg/m2). Laboratory tests indicated a persistent microscopic hematuria without proteinuria and repeated urinary infections. Abdominal-pelvic ultrasound with Doppler showed a dilated left renal vein(LRV) up to 10 mm left of the paraaortic (Nutcracker syndrome) and duodenal obstruction with distension at this level, also confirmed by gastroduodenoscopy (EGD) (Wilkie syndrome). Abdominal-pelvic angioCT results indicated a malformation of the left renal vein dilated by compression in the aorto-mesenteric clamp and communicating with an aberrant left paravertebral and paraspinal network extending to L1 and L5 and a thrombosis of the left ovarian vein. The patient benefited from conservative treatment.

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last seen: 2026-05-20T01:45:00.602351+00:00