Bromelain: Unveiling Its Potential as a Natural Anti-inflammatory Agent through Effective Binding to Apoptosis-Associated Speck-Like Containing CARD (ASC)

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Abstract

This theoretical study presents a novel perspective on the potential anti-inflammatory properties of Bromelain, a natural agent extracted from pineapple stems. The investigation explores the binding capabilities of Bromelain to Apoptosis-associated speck-like containing CARD (ASC), a crucial adapter molecule known for its involvement in inflammatory processes and inflammasome formation. For the first time, these findings suggest that Bromelain exhibits a notable affinity for ASC, indicating its promising role as a natural anti-inflammatory agent. This study sheds light on the molecular interactions that may contribute to Bromelain's therapeutic potential in modulating inflammatory responses.

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europepmc
last seen: 2026-05-20T01:45:00.602351+00:00