Is there any difference in between patients with primary endometriomas and recurrent endometriomas?

In: Istanbul Medical Journal · 2017 · doi:10.5152/imj.2017.27136 · W2774844485
article OA: closed CC0
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This retrospective study compared patients with primary versus recurrent endometriomas and found no significant demographic or clinical differences, though recurrent cases had larger cysts and higher CA-125 levels.

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This retrospective cohort study evaluated 151 patients who underwent surgery for endometriomas to identify predictive factors associated with disease recurrence. The researchers compared demographic and clinical characteristics between those receiving primary surgery and those undergoing repeat procedures for recurrent cysts. Results indicated that while recurrent cases presented with larger cysts and higher cancer antigen-125 levels, no significant differences existed in overall demographic or clinical profiles between the two groups. Consequently, the authors concluded that it is not possible to predict which patients will experience recurrence based on these variables, emphasizing careful surgical technique to preserve ovarian reserve. This paper is centrally about endometriosis — specifically focusing on the clinical comparison of primary versus recurrent endometrioma management.

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Abstract

Introduction: Repeated surgery for recurrent endometriomas is harmful to the ovarian reserve. The aim of the study was to identify predictive factors determining recurrence of endometriomas based on demographic and clinical characteristics.

Methods

A total of 151 patients who underwent surgery for endometriomas between May 2014 and May 2016 were included in this retrospective cohort study. The patients were grouped according to the presence of recurrent surgery for endometriomas and compared based on demographic and clinical characteristics.

Results

A total of 8 patients had repeated surgery for recurrent endometriomas. The patients with recurrent endometriomas had larger cysts and higher cancer antigen-125 levels. There is no statistically significant difference between patients who underwent surgical treatment primarily or secondarily.

Conclusion

There was no significant difference found in patients who underwent primary or secondary surgery for endometriomas according to demographic and clinical characteristics. It was found that it is not possible to predict the patients in whom endometriomas will recur. Therefore, excision of the cyst in the first surgery should be carefully performed to minimize the ovarian damage and delay recurrence.

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