Binding mechanism of SARS-CoV-2 spike protein with human ACE2 receptor

Binding mechanism of SARS-CoV-2 spike protein with human ACE2 receptor | Research Square window.SnipcartSettings = { analytics: { enabled: false } }; (function() { var accessVector = localStorage.getItem('access_vector') || ''; window.dataLayer = window.dataLayer || []; if (accessVector) { window.dataLayer.push({ user: { profile: { profileInfo: { snid: accessVector } } } }); } })(); (function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start':new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0],j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src='https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f);})(window,document,'script','dataLayer','GTM-K279D39R'); Browse Preprints In Review Journals COVID-19 Preprints AJE Video Bytes Research Tools Research Promotion AJE Professional Editing AJE Rubriq About Preprint Platform In Review Editorial Policies Our Team Advisory Board Help Center Sign In Submit a Preprint Cite Share Download PDF Research Article Binding mechanism of SARS-CoV-2 spike protein with human ACE2 receptor Rajendra P Koirala, Bidhya Thapa, Shyam P Khanal, Jhulan Powrel, and 2 more This is a preprint; it has not been peer reviewed by a journal. https://doi.org/ 10.21203/rs.3.rs-71923/v1 This work is licensed under a CC BY 4.0 License Status: Posted Version 1 posted You are reading this latest preprint version Abstract SARS-CoV-2 virus interacts via C-terminal domain of spike protein to human cell receptor protein hACE2. Amino acid residues residing at the interface play vital role in binding of SARS-CoV-2 CTD to hACE2. The detailed atomic level inves- tigation of interactions at binding interface of SARS-CoV-2 CTD/hACE2 provides indispensable information on better understanding of location for drug target. In the present work, we have studied the dynamical behaviour of the complex by ana- lyzing the molecular dynamics (MD) trajectories. The major interacting residues of SARS-CoV-2 CTD and hACE2 have been identified by analyzing the non-bonded interactions such as hydrogen bondings, salt bridges, hydrophobic interactions, van der Waals interactions etc. Umbrella sampling method has been used to estimate the binding free energy for in-depth understanding of binding mechanism between virus protein and host receptor. The binding free energy difference, key residues at the interface, important atomic interactions and contact surface areas have been compared with the molecular complex of SARS-CoV and hACE2. Relatively larger contact surface area, more non-bonded interactions as well as greater binding free energy provide the evidence for favorable binding of SARS-CoV-2 with hACE2 receptor than SARS-CoV. Biophysics SARS-COV 2 hACE2 Spike protein Binding mechanism Figures Figure 1 Figure 2 Figure 3 Figure 4 Figure 5 Figure 6 Figure 7 Figure 8 Full Text Tables Supplementary Files CORONASupplementarymaterials.pdf Cite Share Download PDF Status: Posted Version 1 posted You are reading this latest preprint version Research Square lets you share your work early, gain feedback from the community, and start making changes to your manuscript prior to peer review in a journal. As a division of Research Square Company, we’re committed to making research communication faster, fairer, and more useful. We do this by developing innovative software and high quality services for the global research community. Our growing team is made up of researchers and industry professionals working together to solve the most critical problems facing scientific publishing. Also discoverable on Platform About Our Team In Review Editorial Policies Advisory Board Help Center Resources Author Services Accessibility API Access RSS feed Manage Cookie Preferences © Research Square 2026 | ISSN 2693-5015 (online) Privacy Policy Terms of Service Do Not Sell My Personal Information {"props":{"pageProps":{"initialData":{"identity":"rs-71923","acceptedTermsAndConditions":true,"allowDirectSubmit":true,"archivedVersions":[],"articleType":"Research Article","associatedPublications":[],"authors":[{"id":2005593,"identity":"6fd24771-a5bb-4102-84af-97cf2ae7e333","order_by":0,"name":"Rajendra P Koirala","email":"","orcid":"","institution":"Tribhuvan University Kathmandu","correspondingAuthor":false,"submittingAuthor":false,"prefix":"","firstName":"Rajendra","middleName":"P","lastName":"Koirala","suffix":""},{"id":2005594,"identity":"704654ef-d965-4b04-849e-f7346996de99","order_by":1,"name":"Bidhya Thapa","email":"","orcid":"","institution":"Padhma Kanya Campus Tribhuvan 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Kathmandu","correspondingAuthor":true,"submittingAuthor":false,"prefix":"","firstName":"Narayan","middleName":"P","lastName":"Adhikari","suffix":""}],"badges":[],"createdAt":"2020-09-04 03:35:22","currentVersionCode":1,"declarations":{"humanSubjects":false,"vertebrateSubjects":false,"conflictsOfInterestStatement":true,"humanSubjectEthicalGuidelines":false,"humanSubjectConsent":false,"humanSubjectClinicalTrial":false,"humanSubjectCaseReport":false,"vertebrateSubjectEthicalGuidelines":false,"coiExplicitlySet":false},"doi":"10.21203/rs.3.rs-71923/v1","doiUrl":"https://doi.org/10.21203/rs.3.rs-71923/v1","draftVersion":[],"editorialEvents":[],"editorialNote":"","failedWorkflow":false,"files":[{"id":2303743,"identity":"978454be-6f96-47bd-9396-57f118f55795","added_by":"auto","created_at":"2020-09-08 18:52:19","extension":"png","order_by":1,"title":"Figure 1","display":"","copyAsset":false,"role":"figure","size":68238,"visible":true,"origin":"","legend":"RMSD of SARS-CoV-2 CTD/hACE2 and 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The contact residues which can form potential hydrogen bonds are shown as sticks \u0026 labelled by 1 residue letter (for 0th frame).","description":"","filename":"Fig4.png","url":"https://assets-eu.researchsquare.com/files/rs-71923/v1/Fig4.png"},{"id":2303747,"identity":"b11fa82e-445c-4062-baf1-73ca1659d8ab","added_by":"auto","created_at":"2020-09-08 18:52:19","extension":"png","order_by":5,"title":"Figure 5","display":"","copyAsset":false,"role":"figure","size":294725,"visible":true,"origin":"","legend":"Details of hydrogen bondings at the three key contact sites on binding interface between SARS-CoV-2 CTD and hACE2 receptor. hACE2 receptor is shown in green and SARS-CoV-2 CTD is shown in magenta color. The contact residues which can form potential hydrogen bonds are shown as sticks \u0026 labelled by 1 residue letter (for 0th frame).","description":"","filename":"Fig5.png","url":"https://assets-eu.researchsquare.com/files/rs-71923/v1/Fig5.png"},{"id":2303748,"identity":"e9da4488-c90d-4280-b28f-30dbd7cc2c9f","added_by":"auto","created_at":"2020-09-08 18:52:19","extension":"png","order_by":6,"title":"Figure 6","display":"","copyAsset":false,"role":"figure","size":41627,"visible":true,"origin":"","legend":" Comparison of time evolution of salt-bridge bond length at the interface of SARS-CoV RBD/hACE2 and SARS-CoV-2 CTD/hACE2.","description":"","filename":"Fig6.png","url":"https://assets-eu.researchsquare.com/files/rs-71923/v1/Fig6.png"},{"id":2303749,"identity":"10f973db-adad-45c6-b0a2-74c36c6f1b86","added_by":"auto","created_at":"2020-09-08 18:52:20","extension":"png","order_by":7,"title":"Figure 7","display":"","copyAsset":false,"role":"figure","size":405016,"visible":true,"origin":"","legend":"Comparison of electrostatic and vdw interactions of SARS-CoV-2 CTD and SARS-CoV RBD with hACE2.","description":"","filename":"Fig7.png","url":"https://assets-eu.researchsquare.com/files/rs-71923/v1/Fig7.png"},{"id":2303750,"identity":"ef616923-ec26-47b9-a178-abeddebacaa4","added_by":"auto","created_at":"2020-09-08 18:52:20","extension":"png","order_by":8,"title":"Figure 8","display":"","copyAsset":false,"role":"figure","size":8496,"visible":true,"origin":"","legend":"Free energy curve for SARS-CoV-2 CTD/hACE2 and SARS-CoV RBD/hACE2 during the translation of spikes CTD/RBD from hACE2.","description":"","filename":"Fig8.png","url":"https://assets-eu.researchsquare.com/files/rs-71923/v1/Fig8.png"},{"id":13529167,"identity":"ea966911-2f55-41ef-bed6-e09040d22769","added_by":"auto","created_at":"2021-09-17 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JUfmxkW8/127K+w4ZHGMrEKn8WdfdF/ofkHnORYWPcbTBu7aBNSQ8FwFMOj30++gqBEctU2jryWJrQegQcKMQ0wcZQhM/PIYtQHZdhdn4lE6SXpWMlvtfDPbf/48vZwkr4eiLEHklRO8ctRtK7gwND0//fu1qv3qAdrWjJa+EMo/9dq/7J/4zX67CzZ6RWaVbSIIJCUoPkxTQXdXnJqkQbMOGc3OBV//KQO9NhSlAvm380cE+Juwn5ciri4FVWmEOHRmTT6+/UHNDtSn72V9lLG1+Z7u5UXKJL3+AszGU+nJ1Ta4espA+ceevow+AyyhqXES7nEEK4PUoquTnn2NtXRwmnEbb36SYk4G8bUtMG4+wGkZ3CKEZu0n03eeY5ecmb7gPa2FHL0MuoxapECclOkKFC2aSK8+cEd3MXElJQGajeStnVEzz5/NvHaodovWX3awc4NRcsj5KejSal1Baspev2enZohxGMdYA29Al/oSCEHi0SAZUSL0zwJAhZZE3DaAfrNqGxotOJUPvx83F3LaMF++NLziyKuQ55mxKIk3LRycefZ8hoKe5ZIrbZzZ/5D/+ehLye1Q8rUBFFSUN5mU/9/rKInEzJK3p/n8E97xVZSBSF1B4FeC6oqXtR70dkCZXkrvOZCSDgdYUo7jkKDXVrMzec9Xyp7n7KLsO/f3jqiVQAW9luPnfw27L4Sgp4abGOWffDkDMoMGS3ZDgBSx9gAM84Oq9O3IbRoLNff8qbAvC8OpCr9La0SZk2938SQetZMEP7/ur9mRUt12uck0ypQ9ioYLsgRuj6LhC+427b0Xww9sfTb7bxORjZZxtKCg60JJxHMMsCRqtlXYpmHxd4jWXySX1CFos86O6iuXmjrolaZoFci/Xdb+CPfzYuLvUph/NpyPb39Aoz68iwJ0nY17YF0s0b08UibO/lPQwDIKLrnF09pw10x2idnDCI965+5o7RmL/goi0lRwXxz7TxHI/2lWgeZOxP9pyO+51ap7QO92Xrt0TAZCb4dacjJO2plhO7J+DPc3KdgUgi/IMu5GOW4KaOKBXbOk5gcbM+CEwRKthXCKLyMPunoDvdjl7nFR3xoct1bmlnE3jZblMpPJwoqKbn/ElZQU1MyQpiCjfoAZH6hZ53mdfTYY9ForMyq5+0/LMsKWX5QcovlbtERNzf50vvtPCooklV1YDc07TmfA/siHulTJRwOJiBJBvwsBFZr2NbNnDbDgUOXo3O8pVPk72CcuecmKZM6YypMCA6840VTo7SNNTk49u8+Amh86f/YBXAsYI8szDpnZV3DK/++OU5YxyXErWm2I8yaT8tLv8omE3j7prFl7/ykQqPUIXMhg/qdBxih/1IR54lfX0jOyvrrJ9oJp+2sQ84Mga81/UBO2qkxFxCYI+PrPFGRuz2n8kW7+cIsr8Sja8jloLEfOcIx1BHwb4bpGpJa9DzqIuqKI/ksStQeA9SYoIHx9yuDsWfG7r52KWE5CUEeEth0Ag+C8BdnZUdpdHIlH7SThV4vO5oykL/abn7NyiKLhoh4mmoaDiysJ11s6ixziaEGw0UcUgFpwnM6BM+LQNWVGGXf/Kei9rPS/Uk3+nVOdnRTZaQuQrUD+7Xz7Q6qfFxN/l4L+2QS2yP5YmbC3EUTLydIsRVJSakG1uoUgbrppz9/BV4Pab3JLzpgspEnf2Tf00FiW91Vlc48HdNALbl195+Nf+3Q6I9lrvlhX0dBLHweCCZ6pyFYo0orq2DOKf/Zr6yrhaSWznrjU4/qbK14+79yklmg5XpqVwmSGPaoUz/nbMNz4L2cblXXqrifTjNrJl+4/I/a2UxXZ25LSipRMVQR8Q53KyuNaM2nWX9D1jTALvcDEMX9XXKMjLeb25nZjS3FSUkpmfoP1Tw8/hVDQ97O2rKBEfRU+ytA3NNRZtvPLSrXFA832kH+kqzL3MGFq14CxgApM2C+fqchRJG0vUurpA6WwAnWq+pYrJHmlpV6l6/8TZgAemuU8ZfI39sBYxRn5811rJ9WiJd1wmVOa4OSQ4TgryvY+5vxtyD92X9dwoqXzOtnZUt9wifF5v1YOKf9Tc+X+MqJTr7mMRsGAb1BXlluqNvWSpg5Dn2PIWLHzq2/VPc9g1y79aHEiUoCOoeC7i9pzROcNKyh45OQwrPyq4mPtQIfbWw1GzVdJSYrMwlrr6MuIFJqZA8niWorWQKig7xeD8ig8dg7yq7sVOX87dl9bc4T93uKalu6J5Gvjd484bxDJlKNUKTp/m7Sd9y7Ih5p2Ghu/gadVs6tNEa3we2ztKAOwjbd0OJjtFLD35ffd8E1Rwd9yKE18D0KWSlUhOycvA5rb/yq76Dt1S2NdVUOr7dk87IiOFBRUqM6pamoNQ3LaQv3tNJ6qyElLUuRUmsLVSy157upgz5aEFOCqA56HogHGjSq3rAs1Z0ngAXXJHuA/noFwb9kS7njhHfNj/bqacJ/T44p0XGJgR1SdW3bOBMTueE2t2TPEnng0DUcsPiZ2H0GnQsJI6aF0DxNFOdFkLbOsAFCk5tcbnZNIYLG2oKDrQkEdodW0dpIWkntgFRb/UkN9Syd5vbPlRIPu/hj8ntvxtnL6QLhtf3e5dZJbQxIVKLh9PHJE+cxl1I0L+nkmJSHr6VI2ha2d/8BgMJ8foVHTaXn7Iz7E9gdk1nGhe037Ix5AL/xTc33HkG8p+ObvN1FG5U0n4HP94qYHv4BT/UUmdLSK2QCAqdd1qLz9MWtYwJ1b97SlGd/yDR3MJoLtDwwGs6ksjXW39W1Uny5lf1DzzrYOF7vu9eEA4+OBrvUWOr405zyn3ZQDwDEC58ozkEcstKK3jdlDgPlg4K7P1Hp7xBkZYHlYn1fOWQTBbC7Y/sBgMJvIiveHC/Ta1odCLY0/6ruuLkreU63vvetmZ5ep1442k5PZIrYRLI0Yi9OYKXnARw4FF/A5TAShj+P8LSZGglNu68X6mpOE8YbVetPcfraxsdXMrL9gtgJsf2AwGAwGg9lqsP2BwWAwGAxmq8H2BwaDwWAwmK0G2x8YDAaDwWC2Gmx/YDAYDAaD2Wqw/YHZDOQdfn8cFl4+HcMHBzAYDCZx+CTsj5UX1trCTIV0ZN2VcWttPvhR7Fx5a6HmPH2aSuU5ddn+Ksufn7SDm5B/5HrzVXfYf+toT2Np6TE1cUZZcVTT535maWoVByagpt0/PZULNAC9TDYcKq07Q6iVFZXn+p65LVU6xuUwF9lEQv7h7uZrG3B2kfI/62uqVl44VZb7nUXCwX9g3NqQn5kiE8eOT9QiI7iudc8oK4/B6JqLT/XFF13BFb/7JtECPU4mJedXn6MjpxJEi+powcZqOwxV1VB6qE59Tq2sqtR8/+xZb1WrRN3LFQf5Pm6CXinZfLaovi3MP3jS+HCc71oxVilzCU46zZqKgsJSJbyrsuaCzfNucaSjOEp8gFVUdbSPUUVOhbo34g90NTAxQEC3yIpdpSqS8/2HE0WUtD/slMyi79SweuhgvDtLVbCyWlTf5KQmw1Dp0LknyHUOEG5+NboQ/Zqb/bWK63B5U5l3akuyQebC/r5jJWoX/enwCRdz3aKPyj/X/oAhghQ5558wfYTI7T8X6LPo49of0L3uzoxm5+KMQ7WHjZr2aUJN3Tt2uJsNW7A4RtaU6FzswB/w9Z/M4kQ/CQOjSyRzwx9wWH5OHvpG537HpBGc6K+XDnccLZHVxRfmY8f6eQ6O42fOReyDQbqhz+89cp6goLrFYH9EzS34eW7EWLGzmGDczEMCvoHzR4tzkyNlhxE3hFVBvXPrSvYw0VOhT25d7XeqltPVBXlFqptxelOGgTAOlbQzEZdgavfqszjP5xC1OKh5cm+DQsxJK7s2Es5PzFIOQ/mfGsvyYA2FEwn+NdB8tHhf1PhEDDN2ZWZSynE7DIvIJeiz1tX0v5bVk+CrQV19japZXf1ldlFTD+uhPxpriTLoas0NB0ij6yqiPyjUUTnTsyHV4jUfyv/cptqfy0ac2XzWCv8kS9QuWhpBJ/+PYB3F/KewbtHL8s+1P/weq6a6yTbOjHMJbn+g0FCfplLygdEmywg6TDZgcUidcdDMDYNEea3lhSL7Y8ljLEpKSkGRkwSg6FN8H1DUpLU8XdwOoiSCWHxM7G1kI/ytC/iimramIsVmf0TPLYxfJRVaedFj/BpGFWPSlrI/oBBsNfQUxdJTQ+1lNl4jDF6YXHz1jzjWxd451Xsj8V0hy5PWKom6X6M4IvsD1OWofnckqFjsUmaBYQ6z0tiYXhGWR42FX8TQS9KxP0TuzKlXtu8IFKtZEv+IoZE1klAoweRS4x+iyTwea4oyNG07pXGyTUZof4As/Wk+avKgHIntDwhQ7J1pBfqnG+HkbU1iHIQWR/XN/CawjoFZ0Mn/I8D2Rxx8Mvs/Etz++ISVkgd8Cd4L48QywGjXKGZmBPB+2SjsQJeH9Ye+rf4qNSnXwIbYDoMCPKLYsxGAEVMpmpmPlgjNwqj+a04UzfiJTZFisj+i5hYOvcnJu2AgTSHAtqiMjMrS9sdqaFh/rM8HY2CeboiMr9SCo2mbeMSNBkifDqcZgfJZK8V90BqVj/RfkE+oG+GZ6pilzADNoOSkfG04cFsE6Fc7it0SARrHCn6YdVC9d441D8m6cp/t/67BHpm8hA7Rk1KUnG9ExCBKUHYdE4wUguqKpz+zDnUHXR5p+4OOz5xctSWBS2IbhIAZV/ndB9sf/0Q+4WJi+0OWqFLH9scWAV6CS3YzM/+I979rd6WkV998wZn2X5l4/AuKuMtCvXcbjpLP/gv6UIkRBfyq25W0s7rnD87ujcDEL4/50XejJ8IA37kFg1xcbJj9ET23aDhJ2q2OvBNzWHlm3H+e7QME9seElbAhHZt+ZP31La113KDecMhX7NC6I8JYA79bm5+UXtvzIrxwAOX3yy+CyMdrVj7KCb/rQiHvwwNzjFJmgXHGU5O+0DgDYlsHprw/pl5yzkXsTUqutk2FrwU1D4xjqWpHIMlyA8Gj+o9WobGIklp6+QdnszaqK57+BGeePac31sjYH/RkUlqZ1StRHRtMLINQwDdwJkchaAKfSR/4CRfzn2l/wC17mrp6rekGNzzxasjv+V5Tc0JrJk2a6irtz2j9cmHM1lqvvkxaLaSBOPlNGWxpS3/amk+qO29YrdcNxIlv8i+4goFx64mi7DROK0VS39ega9VcNPWSnZqa+s6hcOBswbABt4K21MAY61c1VbXawVfyFUotjd1prm/uJC1WsoM4eTifcL3nbWhdmXfqSmBO6E6B3X6Y2mi5b2w5eTAjRzP4+oW9TQP3lGWWqgiCDmVO+YdJzTkD2WtSf1PS2IciXTFIV1cceQaE/CM3NRoDabmqLitv7HtG9+nsVtw9ZyzfG1qOl2bkNw2idW6ZxKNkUoZJW0Uu//U6ONVfDyNcKzILjp5q7/rhV694D6jfrTtFet/LvilSk/21O1Ea+482tnXde+yVyMlaidDM25XbKqNaBgC0Z6JBddF002K60NBgGESKBPdRnqvOT07OLD1BEOHo3hKgQaK8894NgugkyQuVBTXmEcEugei5RVsTkso578Ry8O0PYO1918fp+EJvn3TWNlwP77Ggxs2FUdanpKCm7tWmK5KSUjILvm1s777363/F8ouh8kX2BzXr1OQpQOsIh6ePScosQI4pSUnF5IREZrhIi5KFNnpSS0h22QeYNUcN7veyiVJv/2WobeoKS5P601y4TThtwyN2UYYR2x8R5OwPejJpm8qxwPwvBTU3QhIaw3WLSV1WcrrPQ5ci3GU1D7hv6bRGscaifcHf1lw0WUijVteq3Lct6iA0P2rVwYbCbqFts3tR9aByHTTc69ESxuuk9khBZVdk949EF8Tv5Nmtnalneu4bWk6W7s5peigbXx4QTvDGlRYV0RvepgO376gaQFksposNKh3d14UTb7nv7tNrw9mb/e8DQ2s7GKFUB/drBtAIFc5VwUndxeZ2s8V8vqaszjAUjhrDtz8kyoW2P58szVIkKbJP3ANvYv5fiZxtSal5FY1oy7NkbywxCIJvA17rkTTFV/qRaGKHbJHo42bz7Y/l52R5QY3NCzNNzQ0bynYTjxfBR9CvZRwwetBMJ/W6v2Z3gf7popcsKQn3KUtj5nrCNeslq0rIl6z2eMxlWroCUFPk2x9ZZxxMGKrQvPPcrtwLT+bRvzz7A46IGYVGD5olpmb7a7YV60fEb2wI+JpVxfYdVHCsCxhE8HkCgwY2/kinAH9UpBd2Dgd8PzSUnO73gdv5SgmX1UvYOgFlz9qJ6gQiXV3x5BmwOKTeo7RNwq4WXpyyN/JKBzOXnFrYORqYuNdw+Hj/X5Rs4vKZlAMmXqgf5V8FmpPtfGVOOKDXjjIj/xzK4lDz0T64LxTO2WYkwV263J8hwCazEVU5qWAgRKR9YxSM6DEkAgkN63fnSnTfHKjph015R0hmtR7u/ivPY4dJgdxlgFclfcGux8ONEYoSkvdmukZukVUhMwLxQVcy50rOnizdpYj24oXWLJLLzS/WECMf8J5wh6jMAxlCKHibRmnWrnyk/ymlxE0rhLx8pqK0iuhjwsqzrC3lMLy1G1miiZIGzs8lh6WzMtZdoZOxXKVA9lZaidkjb1zELsowqK7WZX9ErRBq0Xl2T41tEg6iodn+upSdrS5WTDBZxfbiTgmNpfwuXUFuvZ1ZpKLmhzQ7pTcgc0H5FBQBlUvBdlwrz4x5GazlJ9u/8dOBKShSD3SOvvPdO1Vy/J6Pyb6YxTHy211sYf3DV4p3o8JSrwebisvJF0y2gi/I8mLmHYxOPK2sM5K91B25p+/Tc2PQ3s1WO5lXDpSrnEYHbf+gDcIp+ZoheooKFZMRRJR+2z+iL04uuAT3ZgVf9DQQA4xlLHnLG5lBEJ40rK/SObgqLcGWij4uNtv+gGuxyduamADWK8/N+1PR6Q808xl5fQGVcix5O/Hrv9t3p5Vr7S/o8SnkuX/LMzuq359WqrOP0zPAS55b9z1ho4KvmrzmF3hCbE9j9Bteyg4baK9WcViWq3/3V+/YTjzhdYRh4HCVVaodYA4Khjy3bqGHcxMEiO2PJMEwLMjelF25C56pg5/RyjczhStTXXHlGfB2QJm2S2mfQv+AHjAtMkMMM5fMWyKRTVwuk/JM2yqEk64RKL/XNXC9pWyXIilX7ZxlvoVt4+Ix2yv0dFT8pEg7FxHyT/w2cONcWVZKUtZZZ2RXfOyJgNrYyUQzlwZqZnJ1fzh/qEIyGdtLIHcZkAKEd72gquO12jVzu775j8DMsKnikOwIhCz+/MaBv9bZfVD+CddPN1oOZSmSs9RDjK5DYql8pP9MPqngzLCNOLizWDsk3W/KSZlDTPMfUUXJgLbNMktU4LOKv1cpKnDCJjtnjYMnWzr/EXUnSuit/URa2gk7/YYGr9+rdTPvzfIai9aPthOuyDoXVLk1ByGUoJT9EZkr4qQj37/x00Ep7NaPRu+FoKrbKpN3qhy05ANj5oOK9FOO+RA8hJh8rD+yAx2NO8xgLJG9SH3CfEQavqh0sw7VTsV+8xi8F6VDd/XR++1lj7lkRy5h/41s7Qgf+5K+5eG/ZQbB2NhS0cfFZtsfoPq2S1jlcFxPDr8OAW4SpSlAopN/OZq/Qm9aitScKnhEHtis0z83F8ApfPBClFN53sbMHUmpJu9BsLIUFbZp8JGjPWihNKOU6GYebO0mSjMkcsgQnHYQBfQLWWpeJXGHWYPgq6OU/SHV9oRPAf3s8BPHXaMyjxW5dHXFmWcWMGA8fezoNyqzUyJKI8j52omLMykPrAd+wZfGXKP8lW9gvBdzGjY8YldYpGyG3gwAqtLMJAU84Mr8CqCWnrtHeYMQnIgqVnD3Ua6ZSBigFZnRDAikmfyCcno9Ue1JwlcAsf2xZm6jbhoAt7eYWEMQKjkn8fD+D+EmG3hUtfxA/MaH/7nLwx/rlsbMZQresdVYKh/VIbcSlof1uds4B9FjkTKHqPs/VucdLR3uUHRRsqyMmfcr0JrU+991Fd1oCIkBeKT228K1T73GLsowKJPCDoQBqZaE/YFa8Tb+SSVpYK/wBPUKsl0WV2MnbRXp/K4mpkGInyCNoA+MpBOlC+KnI0hBDmRVSFTg4qi+UNCJofTpd0XZ7EHgdVHsD1RjiqO2aSDLSDprda1U0GutTEvhrlfK3TIpMwjGxdaIPi422/5A/aNYY1ChxSWh/FOv/cvg7cd+u6tdVZqlyKyyvfzf11N++O714La5TVW6S5FWa4MrGoKKE6smfDTz9sPRHnSX1AuEJJT/9WvwcK/LfssMM7Qtreo2nPTjJAiJ2/6APp3qiw4oDbcc7nGPJSxy6eqKL88A6PLrZFFRvcHmcE+MWOQbEkA+cblMyiOe//D1HePOtUCWJ8jySBnn7cfBWEZ/hoi9MoAm0Sxa03lJFu+IlGLtRMKAGt5d3f83858YeMKWc74VgmRHz/2Iak8SvgKI7I8YchttF8vKM+OJ79mZZ6QwEnIBlUxEjj0HJ/qbjhHstp54mLAeMwpeN6kJspir3jFVPqpDXj4FOY8i5VF4bwRaV6Ocf1ld8XSdsHqp6KIMQ5syu7T/+pf+aHgjCARdHIHbRgK+/rNVxMNYXG7ELMow9HMFHQiDTGtF007cjcZSwLX8+gNFStArPJ3w9Mp3WRswCHESDG8iRuWKJBVJR6ZQEH7GBCnIgfIvUYHICQI/6yh9ejJANnsQeN1a9gczsxJJJ0q5aKj5IaIwKzW9vp/dAS1zS8gvMwjGyFaKPi422/5A05u8ORx6Lzd0LMM/+QY9dj8f/J+SiAkPGlXNtor/7zZxLNKTUq9sVdn0/Dm/4kSqKbf+Aj1Hba9kposR1Nzzp8Kz+QzgxpKITwJqyla1DRm53ATB93Bbn5xEaXjZo2YH6tP3apyzKGFW5O8nfvnF80yyuubiyTMw/+0n03eec9J7X1ileU+/EPNzDpGpkP8nm0npEwkQmDh/4QlYZsIDmUAlStjuGLypnDnOe8GloB8I3hlR8Ohvc/XDvNYGV2f3s2NPLImwrL3/A2mmcNJ+B/OmLq49KfgKwG3SgBhzuzhGVkk5jaAWXZ1n2RVZWriCLhVCve6vI5hVPOiS6/TV8EaK6R+au9Z+S2YB6R/Qj/J2t8FzK7t07CbNGIuD9J+XT5RzXi1Fl7IIuFMqU8L/x+qcS9eGvLxEFWUE2pTJzC9siO38asA3cKHhangP06StuZdrtoiIUZRhUF0JOxAGpFqi8Qm6PMnIJX7lHFISAR3z7NkZ9nLGvDK9oY0DeY398PUXv0trRFcLumhOOvJ9Mj9jok5eBnS0CjTziJypmefPZgLQ44t4/QUuzYAuTT57AJiPKPYHtLnZbROcdKKPNZTPflZnn/LaG3Iiaix9y/CgzCAYE1sr+rjY9P2n1NtHmpwc7h6W82cfzFLQr2J5xqHwVjjK/++OUxbPUEsau/UGfLfgOJ2jHfyF2FdoHGU7hlmHqpzukiRUk7P/FIzBGfTuHgBPe2B3kFHSxTroDPnd1071PJfueMCNaV8zm2QBCw5VDup54TvTDnaVDrkhisf+QO6W2SVhYIo17oEiX3Jpta6gdHXFk2fazGeXxqn5wcYM+Ba45DJqQQ55VUEjnfhSlEyi6ySAL6x7eAMP1PUdZYZfw/6h4SamvGOM8U55rd+cEc5SCL0yoCaRdtjw5G/2uaF5Z0sePREFiCkRFnj+hZ4mlQNNimZUcjctlmWwg4dE7UnAVwC+/RF7bpHTzKwCzZ2I08yQ33OrVfeA89qNRnFhlwAkeKmA9sICfaEeyFV2WJjpXOtNopoxF5aekfXVTbYXMlpEA9JPSyu7/CS8URSeW/m6ysbuu4i1OEj/efmES+ZJ9NQ35e0z3B+OLmUpkP/TnAL13Yj/U3h2oE1np5eZooqSA9oukCShLRLAui3MVXZyKvQQb/pHiphEGQbVlbADYUCqxbM/kP/T/HTxpmABsNNJZbus0LzjdAZMx0cbB1E0lpr/lcgtYN9DqOCkrSZdMKskAfQDpEC7CoApfN6C7DNeH8gfzGT7N37GBCnIQ80MaQoy6gfoTEOlPa+DJin0WZdbxt1/WpZbaR1H/0bJHp0Pgf2RF6kTuP+0iPVKx01Hvt+GKnGsAbnZRfs6s8pJuj+XvMU1JD0IwgNuNWvuP91a0cfFptsfMN++XwzKo/Vak8WsJ3S3Iudvx+5ra46w31tc04Gg60JBHaHVtHaSFpI5fTrnIg7XXbygIa6Q1hudLaeae4f9VGDCfhmFQthepNTb4Tr3gltX3/n41z6dzkj2mi/WVTT00g+CxyZhrAdFWlEdffYV1OtYv66m8rjWTJr1F3Q9LtnoCUA4Bd9d1J4jOm9YSe45rpB/pKuq+Fg7eFZ7q8Go+QqeGyystY6+jGSsmXkcDNxwCsa/SCtStqBzm8FXg9pvckvOmCykSd/ZN/TQWJb3VWVzD1xql6mu2PMMU/hZW1ZQor4Kkzf0DQ11lu38slJt+Y9nIFwVLcTNSHgLycSjZVIOOLfB29zq66tp7P/j95vNNUfqVGcJ9bHS0kbkshpI0ADPaySl59d0RXLid5Oao/mpChiA4+Q5dHIPNInGxoGnv/e01FQeU7W0qOsOlTLCjT0RBri8urb/D6iZuoYTLZ3Xyc6W+oZLtNtsriLxao8HVzNbSfe4m2xVFm2HcUbOXNTr/yeu3MJX7UjQkLONyjp1JNKHTPwX4oyyNCeV2YqIjucxywdh2Akq+KalWGs334S15tzAH497mr+rrGtsIc7UlR5q6AENEPwUa+UHw/FfYCWET2OiN5C0lKzqSxZT++VHf03KSjkq3PgvLU3KmuYuV9iCAUiLUgjl66/5Mmz0R2HFazkEKpwHfze3LFFEyYIivBAtx2EAGlCr1ad5x7zl47+cNA7FsBIU8A3qynJL1aZe0tRh6HMMGSt2fvWtuud3j6zGXkZdK+qR6uvUnTcs5kvNhsstX32RlJpd9J11XLIF0IDx1VydW3bOBPowx2uK2weCtjP5G0lA1VVkV5xps8MJVYkuiN/Jv3wu7EWjE5wcMhyvhKdYQTfa3seev6X8f/brVPUtV0jQn9erdP1/QmWOmr3//lc4gqAxO1+p1WmNNywmoqbyDOOGX5AOaBTS5WqrK8oCciyAb4SgY7n1bWYyai/nYbkkbgE2jXgQBM+jG/j2aAvKkK0VfTxsgf2B+YyAu/m4/k8TC2AelUacPWBW55yXrq95mgCDwXDhzxl8ZEKjptNr2B+JC7Y/MBuKIP5LQrH4wfFfPi2oeWdbh4uzWweDwaxNItkfS2PdbX1b4Xd/U8D2B2ZjgcuE30Xi3yYOiy/Mtd8ya70YIKjXjjbjGivHGAyGh2CBda1loE1mxfvDhZ5nwg1N/xyw/YHZcKBXvuarbvaAQCIQ8g93N1/j+13FYDAYzMcD2x+YzQCepuaE1ProLLx8OoaNDwwGg0kcEsf++Lu/OjO2neQfAjrwHYMH3y1ha4qMwWAwGEzCkTD2BwzowPMYsznM2JVZ0SKnbCVbVGQMBoPBYBKOBLE/qICL2L62Y4YPBjpFLY4jxNQmslVFxmAwnzPRfCV/DJa8T5+z3ngxnzcfzf6g/M9/eUrHLwb4XcR+ntPZjYKa8/wyTMdFBgRdRHpMXg5ZqL+Hzivr283GVtItDCkeN1tU5A9gZdxam5+pSFrbxSeGYeWFtbYQVFlMbhk/K6LWTEJoGnSWqqlUnlOX7a+y/PlPPcIYHWpu5NqFq8Nh71vDPQ2HSuvOEGplReW5vmduS5VOwp8lNe3+6Wm42+QDw0I1lB6qU59TK6sqNd8/e9Zb1SrlE1MuEWpu+OqFa+GAAOsk5Pf0NVU2XFAfyq2yjAlO28XVKqMVFkAFfU6zurIgv0wJi3ykBkYhnRvR10AvtH43STRDn10cp3AEcVZ1dP/G9QkfWuHQcSLtAJB1VNii+rYw/+BJ40MmrjtLrOqxcXwk+wN6cc6LiGflmfErNXLCv7GE5p3ndkYOai95jEdUjjfocyyszDtObUf2yoqHPM+LZxE/W1TkDwaebcf2R1wIPDd/zsCQK4qc808Yd6hRa+YjaxoFo7FnNDsXZxyqPaKgMJ8Gwan+psNmD2NaLT8nD33DugkHP0701wuc4jNA7+nJktHsoNfaQyXtTFwLODbfq88SBBlmkE8E5MRjPtwUDrq2HmCc+ly1cxaGdGECuAiItVVGyycY+0eule08SNBuUiGgyD81H/16X3LYCz7yWc53ig9vdF8q2BPeaBjwDbbX1qha1EcLsr9WMR6EY2GDKpyuDe5tUPo5aVy3/TGrxwbyUewPammkowCYh4WR0G6bwtJTfcEXSUkHIpF74gPKjK5/atzS+kE+5raqyPESGtYf6+M1UWx/xM2m2h+Lo/rmBPG0GAN+j1VT3WQbZ95HE9n+QGGSPmmrEca53HvexUzcoriA/P4HxuZNFw8wKGhoUkqe8ZloVH/nVO/lR/mH0fsk0oiWCAAYf+f3huOzxA8KoRXdA1iMrTJKPlH8oLQsNkBMGGrZYyxURLc/wFWvbDVtqF5A52+s1bmQzYGCxSSnFRtHYlsR26gKF9kfoA5hrP8v9pufo+tjV4+N5GPYH8ueruMnTx5M32TbavFF1xnVya+5keHiBPZQKI6Gf+Sq8cGH+M3coiLHDYy8Vc5votj+iJvNtD9AL1b53T/H/hCQyPbHZkotIXjvJSv2RkYjNEwKNpxRYIAVTbAvD+sPfVv9VWqSMHI1YMJamiEY4SiftVLcq0VLBAEuyCuXeVlfG6g7G2J/RMknqJzy9KRIqGcOsFXuX8P+iLw5/N3/nYYToxFFXkw5LozaKM1GVbiE/YGCg4YXiWJWjw1l6+2PJS956qzzv09AdfBCIW8swMy8+d3ZodknQE3XDM8jR2jadlSxWzfkMrfe8X6AFLamyPET/GugcZ9C0EQ/NfsjMON56plZZzcXG5s3kgV8A2dyFIkSaSJ+sP3x8Vh5Zsz7iok1CKHeu3W7knZW9/zBmfwP0EHYOYDLDEfJZ/8lDymS8ulI4xz8bm1+UnptzwtOGL+ViV9+4aexRiI0YHj+SuZlfW02yP6Ilk8UwjfpC7VTqu9Y8hirZewP8K8eZSz09tHdR29DdF4V+81jTFHp6/dq3Qv0/1HZqAqXsD9WPMa8pORd2t/fw/9iVI8NZqvtD2qq/8Qp+yy1PEGWy8WY3gCoyf4ThH02RE2QxR+wxw1J6IsCZuoMEJgYOF+Rk5akyCqqa0MRAtfmw4tM+YdJzTkD2WtSf1PS2OehV+zYPVapZ3ruG1pOlu7OaXqIdreG/J7vNTUntGbSpKmu0v4sHRtzcdTaqq7OT03KLFXBPUlXmOKgUeFg5/c9xAUj2a2tLK40R9yGUv5nfZo6GJvX1FxV1Tbok68Bam6EJDSG6xaTuqzkdJ8HbTeD27XowJKVrTAO6orfbarM3qbIKmse8K7A/YAtNTBk5VVNVa128FVwNTBubcjPTElKbbTcN7acPJiRoxmELsND/pGbGo2BtFxVl5U39j2LtBlqbrSnqULZdgM+t7ZRrevt/G57hW06jswvjNla69WXSauFNBAnvyljepbgq0GdquGiyWIxXWxQ6WD2aDg93foL2DzgvqXTGknyQmVBjRnuzpsfterOVecnJ+0sVcFtY/zQuHwka5sm/NAb3ADOkdq4wQSaps1iSeWRqpClP23NJ9WdN6zW6wbixDf5F1xBUJYTRdlpHCVHNbOvQdequWjqJTs1NfWdQ+FqF9gfEpUjiURm+LtZV+aduhKYDXpIkFKh1y/sbZqI8qOgptKtDCFdV7FmGCCtrmy295yxfG9oOV6akd80iAKySyuqvM5LMm2r2MZ/yQa9Yu1O8MaryNx/tLGt695jL6eMLH637hTpfQ/n3pPDg1MEaupebboiKSkls+Dbxvbue7/+VyobaySCWJm3H99WZvVFKYV0iwtM2K9w2oVcJGqkewcN93q0hPE6qT1SUNkV2evAECWfMHspSV+wYeujILA/gMWg5nXy1JsnhuMNXeFeNDBuPpCUVBTjMcwNqnCR/YH2IyqY7pT+Jhb12GC21v6gph1nW9G2IzS1sP6VkeiE3jp0p/onoZhAIwTdkni2Kiao4Ku+ypTkncRjTowuoD31GmfMC5cbUOR3TnVJjQ1NwFCv+2uyOPmBWqVIPdA5+s5371TJ8XugMUN9zThg9KBL4PW7C/RPZTSdM3CGoa31go4R5L0UWmCKQ0Cz4U9QQXMKjaNoO1totr9uG3uZCGrReXZPjW0Sjl7wypSdrew6NLToOW8Dc85mlRXGTwpO9ddnFBo9aPKQmu2v2VasH4F1BXOkSC/sHA74fmgoOd3vW15dHFLvUdomYb8Mr0zZy0a8W/E7z2YxU6bBKVt1CnhQaPHd3PvYMw/fe0rICeaXpTFzPRQZ9XqwqbicfMEoUvAFWV5MjxaialxfAbcXd9Jiguu4ihLSi5JG0ljTZo1S24tj5Le72J/8w1eKd6Oflp+T5QWsUs0NG8p2I6WSVJ5FiQqZ9ZJVJeGuOegxl2npNsbPMKqZrDMO8BYIgfvBd+VeeDKP/oWXhu0P2coRIC0dAC81em450tZQDfNVSCg1+VYmXVexZhgiq650zpJTCztHAxP3Gg4f7/+LklPUKIlIARMWOVoElo2NqMpJBeMZIu0bo+AcyuJQ89E+2HXCJYaMJLg/l/c71CLPHaIyL5VJQsHbw0izdiIQuP8gStccrcWh0q3RLpB8FaxQ4GxQhjD2dbR80lZFLO+uzJX0+RfwIpgVfcISLeskl3TFHCFrQyoc1UZKKXHTCiEvn6korSL63NPsywBibfXYaLbS/gC9j/Y7Vp+QAu1UOWbRfxsJNT909rubXvqlHz1mm8oRy1QXH7jP+Wzz9/++rUxPLje/YPoikPj5sw9itj42pMhTduWuNOXAW/gZ6foOrZtRP6RVvF5mzkXsTSoOd9Cg/zqWvJ1wBSRzLOiCETCXnE1MkX4cnRdIKicnUMcImO2vTpbznxZ6az+RlnbCTg88MJHIfCOaVfpSP4r+XXx8/tSPsD7hhvY0ztvG3/3VO2hPcajeCjkzyaurbweUabuU9in0z4S1NI2tEl6J0I10XxBH5mG3mFautb+g3zNCnvu3PIvwdt7aGapYZpgXVuO6Chh+H0IiZvtlThGiIFvbcH9PcljlAmPmgwp4WOA9sMyStzU5FlBeVp6b96eiAyDSyvPrv9tFFTI7qt+fVqqzj9PTwkueW/c96OH8DIsUDDrgSWOGAXgp27/LV44AKemgeuOmBhDbHwIVEuZNrpVBK1airmLOMERWXemcJXOcIMsrapREJEBvO4KmHSHkn/ht4Ma5sqyUpKyzzsj8ATBkLx5jnAKggidlq50yIdYo/4Trpxsth7IUyVnqIY7lFXMiQEaKo7ZpyUKgepBtcQI1kwTJN7KhAdRYKt/aiZ7P9c1/UMGZ34wVx+QzhszWnDMDUWaO5figCke1wZQfZHLYRhzcWawdkg4/KaceG88W2h9LT/WF+RVnWuBkP0GgCbRYrMt48Y/oD+ZUNNFPoR8jHGJjgPI/NR4+DbV/2WMuSU+rtCKDxj9ibLsDX55iYyOLDHRi+InjrlGZx5nPEfXvoWH97uSwmQu4SZSmyDZU0e0A2X58cVRfGLGgATDpNYoDmszTJ45+ozKbMxisUuNkSTp6v1yZd7S1oqaCNmNnlBLdTOLWbqI0g86bbF8DU3+MUk8Jj9c+a6WC2cVNLTiatjGvAvFknnrtaP4KvW0oUnOqCNszP4Vu5/denCFNVI0fVMB12B8MotpGXbbE7WCw3C6UO0BOeSb/ElXIKjX9c3NBOvwuKS2n8ryNXfHhZ1isYHAYUKDlMHQpI4IolSNEQjroe05qEAn7Q1APUsov0cqk6yqODIeRUFdRttdUVMlEJEBaxMsPtfTcPcobS6jgWFexIlMZ8SzwxqEqLFI20/0VoSrNTFJkqIc4Vpv/ucvDGfkAS2PmMgVvN+WaibBAGcnpdvQWJylQAQL5iu2PNfIZdf8HaNeGDuaFimt/0P/S+z/AVYKNGvA0b3mhOh7jY6MqHNUGt/zLw/rcbZxj57Gox8azZfbHosd42sCdn4TKxzP8kVF2uFJySIgVClgL3xm4yw1Q7SIzBNTcCFwONHU2VpUTdumNERC064fRXXgCuxyewhpbfNF7ups9TL820YtMBX0PDc2XzJbr7TWlVZw9FiKg/5n6ogNKwy2He9xjiQxOojbGtMuoHRMXzu3hpiLoECP9uEiDowJd2dQfKFIabI6nE55e7mAAngGNdGAZLPj6Txk4LzTcayJI9DVwk8fJoqJ6kLp7YsTC6VnQTPhXxJBvcdplrCptHPgLfR9H5in/1Gv/MngDsN/ualeVZikyq2z/+V27V3A7yhU9zSCSwgcVUM7+iLYXTKa26Z5R3E2jRsHLMAI9TFxJUhXy8n9fT/nBWOh6cNvcpirdpUirtSG7nF8Wcc3ARydX98MJGXgpo2noLunKESCVGTRfw0kNErf9IdfKpOsq9gxD5NVVmO0oiholEQnE8x9AGZr5M0AgzZdk8Y7I08ErPxjXmH8AM3ZlJv+kxoT1mFG4pgP32HHqdu1EWICMZPfjo9PR/BKiOmcm9qQEKkAgX5H9sWY+o5x/gYukBPt0gf0RgZqwHI8cnQUdfn9TlTbanjkJNqrCxXqFFDvyTRT1GIX3RohZ7WNga+wPKui1HD//K2cLL6NB4eJTM+67NpuxOpvTFOMn+KLnuJ5ZXWbg1ju9SZh+NwZvqDvYo89ikGwih6EDk7a69ORdBcqwo70Vv/v+g2j7T9csMjDw99PmJzzLLjsPCQbUgfr0veyOE3Zwek+bC4I2BoAOoJJ5Pl6jhKLl3B50aekVfEGHGOnHoTe29ORqG8drEOUfe/qSfgngQ03Z6/fs1AwxxWcSeRMeQdEC9o7qK5eaOoYZe25+UJW+necQlvUbLeprQrP2k+k7zzkZQTM9y/uJx79MBEJu45l7I6MP7lhtD1wTYaMujswHXRdKIr0GsCRqtlV8/ye8XTQbzDg+EkvhQwrIihj9x/nJ79IamdYiQL62Xz4z5iXxlpmomefPZvzQVQBvVS448+z5DCWtPM8H/0dUIf/fbeJYxK0O9cpWlV1hmwQf+WUR1Yzc+ot85QiQko5wNgVAjZsLOR0lP1c0vLzJtzLPM8m6mos1w9HVVZBteUWdi5aIFDBh3sosKNS3uXpWG2ngroj97HEJoNJnjvNedinoEyKJ+wYMnnuAWVhkgauNkUE6lkQY4BwSq+ci6HqQa3GSAhUg0D2mxtgbYsln+M1T4P8DdN5PdJFVeKQtEqMyeITmFLP0ibyWNYQ3wALrsK0rJq9UG1XhqDZ4tQ0rhPNysqZ6bApbYn8Ex61HzgjtXFi2FH6vDeoon29/UEue3vrKZts43y6TZslrPdnQz2xQYqG9stC1DJfJ05mNgaKekceyz1abpvia2YiHTNfGgqy08Lod3FV6KZr30hiKTPknX8JzoUCB6raxG9nEIE877HowGCEa90A1WqLNBXEpUJvJOBTZsOL/d8cpkX9ihvde8pACLZFSsz+d70bduqBD5L5Hwo142SVhd4rUO3dHa8+YlGhgplPZpdPQvON0BkzExxlB3znV2UkKrre+xTGyKiOyLSvkd1871fMcPEvU16B3I3abAjU/2JihQFVi1Lr8Qdf5AuJfEpNJMWcePC4tIg5qwXE6R/v7eyDQytwy7m64sly2Y5LUpXUXkGd/oElgtDWEet1/3sIaxHyi1fbMkKYgI+zoiZp1ntfBc2FvH2lycurtjKXB7mqSVh7PUIuoQgZ/IfaxeyQBsw5VOd1P8cuCaoaz/xQMohkFlxhnjjxNk60cAdLSgR/hGwVbCUtesoLr+IefKxqe1KK1Mum6ijXD0dWVXwkIaUWdjpaIFPAtmfcSjPQq7bDhyd9sLYTmnS15VbeZEyjgdf+bM8JZisUhdYaCY5KCQSstrezyk/C+RXiM4mtmCgr+G0siNOj8C207ShKtxUkKVICgVfLtj1jzifyfZhWp7zwPdymU/1lf62V7ZBpD2v6g/C5dwUF6Uxf8XLhf2dnLrKlZu4lDavT0NQe4japwVBuR8gOQGxJ6PYvy9hnuD0dXj81hk+0P6m+n8RQ6sJpTaQrbUaDS7+rOVGQrkpLSipQtVx3MjgpQRwL7A1nBvGUaSYLTTlNjRV5q0rZs+BhWGEsem+4U9HuftL1Iea7DgU7E0Kwx/wEumBvtOVGQXVKnblbVVde33vHMvxvr11UWfFmhUqtq6nVDf0vLJY4iU8veBx1EXVFGJRklPlTw1aD2m9ySMyYLadJ39g09NJblfVXZ3POfEXsbKh1MUEu6wxuOQv6x+9qaI/D8nllP6Cwu/iZnLpT/qblyfxnRqddcdkwHYaQAmElFWlEdQf426b5JKIvSQK1WnKIPf1L+P/u1dZXwzCFI+lKPK6ysAgK+QV1Zbqna1EuaOgx9jiFjxc6vvlX3PGPLCfeX7S63ckQCvpsHNVxTeVxrJs36C7oe13QwMGG/fKYiRwEl2EyfkwTXBX0/a8sKStRXYZUY+oaGOst2flmptniWKPQmze7fBqQWKo1D9EJbjJkHb9gFdYRW09pJWkjOeUt4u05V33KFJK+01Kt0tEvmFW9ECryjgOsoYCvpHneTrTCchCKn4sxleCKamhsxV+eWnTMBSToEtnWYqLUdnBwyHGdL3d7HnL8FdfiLQXmUVZJbkfO3IuWRqpA5F3G47uIFDXGFtN7obDnV3Dvsp7hl0aPj3AtuXX3n41/7dDoj2Wu+WFfR0Es/iK9pSKwSlSNRXDnpoKGiq6r4WDt4UHurwaj5KilJkVlYax19KVYhrtTotiPXyuDiu0xdxZZhdLu0uv7HMxCuhBaO8kgpalSdlwS+7XD9f4BhsrFx4OnvPS01lcdULS3qukOljDiA4AwnS3cpktLza7oiOux3k5qj+amKJMWu0pPnUA8wYa05N/DH457m7yrrGluIM3WlhxoYb+KxJ0KzuKb/D+kWBx8k7hP4CFrl5G/sqfiKM213B3+MK5+g5sPxX1paGpU16uuRHhWetxfHf2lRK0uzQVK0/bfy0npoB9MdhWGmptYc4DagwoPh+C+wVwkf46dnd1Kyqi9ZTO2XH/01Kasem8gW7j9dG7H9gVh4dOFKdPsjXpa81mOFjT/K7//YSgK+flVuWZdsP4KJnaVR86FvdY9ZwwJuULirLc0pt9KnWTGYz4fAmLmc4/80wQDm0d4K5mD/Z07g10udGzvA/WNIfPsjNO+82hH1pHucBHwDF+p1j3zBwBvfrMzr+xYQ8Ll+YY5fB5zqLzZ3m/FnAjxumnrCPsdtywuj+q+jTXRhMJ8o/PgvCQX1gfFfPiE2fID7J5Ho9gc17WjrcL7dMDUN+OyXW2nXgQHnuTPr8AuyQcAF5wx6y97qgkO1bXc8gXkxcgSm3X2t9cdOEp2k1WoxX9I0niLMzsSY6MJgtpjApE0ViX+bOCx7zIfqrVEWnT8b4ADX5kB+qz9HEsb+WBp39JnURRlwOeque2ZT5EEt/XG1OJlZgEtK2saPK7jFBHwOE0HoYzh/i8FgMOuCmhu5duHq8OZ6sYwPam746oVrm+xYE/OPIKHmPzAYDAazocgeDP5ILHmfPsfGBwaC7Q8MBoPBYDBbDbY/MBgMBoPBbDXY/sBgMBgMBrPVbJn9wfXick6tPFJD3PH450b0NSK3tVzeucmLyNVMkiK7Qs11NbPiHWguy1IkKbJKVTfELmgCE/YrBPL3lZxffQ76hDmrOlqUX3zS+ICJnImAl6GIyeHLAKerC/KKVDfDrlegryTaf0vkorOqivzsosYuWQdcG8XKvFNXkp0Wl9f9lXFrbX6mYlPC+yUGKy+stYWghCKvoxgMBoP5Z7A19gfyYrvzIME4sAMAc+Sn5qNf70uOYVidtytTklKU3BA7NBPWQyeFPs65ICe9HJ+z4KH36rOyyoz8wybCy8A3L8iy9OTiq39EfIKJ/deG/GM2Ve5+NsLZZsJ1gh4jYr/OawPDfyhyzj8Ju9JLaJBEsP2BwWAw/0y2wP6ggl5rpUQUH2rZYyxUxDKswnFRHEGRmrrzXVM4fLAUYsOCDuvMi8oheRkK3Z60vbr/b+YLCfsDAH1s71QU67lBbjeDNe2P0LD+WB9vJF6P/eH3WDXVTbZxJqRFgoPtDwwGg/kHs/n2R5QoxtQrW+X+GOwPOqBfBi/aJAx9qW52hoOeSCFhWNCxgvgDs8Rl9HfcLyXtD5C1cbIkNVkQ5mPDWcv+gH4/y/kj8Xrsj38W2P7AYDCYfzCbbn+gAJ5JX6idUjHQljzG6piWFRYfEzuTeQH9wMB/RLeGa2EJw4IOh5vPiykscRmMzZjCs3hk7A9mQqUyaiTGDya6/RH8a6Bxn0IwEmP7A4PBYDAJzGbbH/RA/gUbFzsKAd+goaHhgsly03RR1aD7me8z2+/W5icpDoXjFVHe3qM6FHc7CiLDgpof0uxMzWl6yPN3K7Y/lj3mkvQ0Xkw4OfuDnlDZqXLMMl/wofzDpOacgew1qb8paezz0Hta2e2TqS333X16rfE6qT1SUNk1Egk2GPKP9jZU1F0095JGnU5bt0/O/lgctbaqq/NTkzJLVXBj7BUUd5SxPw52ft9DXDCS3drK4kqOi1UYQlpTB+N5mpqrqtoGYSzpwLj1RBHc6IqiWodzeKbnvqHlZOluYaVFCPk932tqTmjN3WwcVPR18NWgTtVw0WSxmC42qHSDr2DNyRV89r8PDK3tZtKkOrhfM4BEH85PwUndxeZ2s8V8vqaszjA0yUpAYH+Es0GaNNVVWqA/Ib/7JoE2FyuyT9wD1eL/lcjZlpSaV9FIwnCR1Jynr6UGRhm9qqmq1dI5XPrT1nxS3XnDar1uIE58k39BJHEMBoPBbACbbX9IrXdIEJwe1OSV93gZm2PJSx7J4w141Hu3bldSagk5jr4LjJlP6qQCL/NAhkVKKXHTCrCQnWcqSo4S1t+FYbJ5l1mt5CVl/s4C9Q9jvNDD0e0PuQK+c6pLamxeeBP1ur8mayfxmI2HDRNUpJV10ntHYLDsDLZ0YOC8VJBx0s5srQ3NO8/tjLb+IjUTgAqlKOgYQSbUiseYF7beqMn+2pxC4yiKChGa7a/bxl6GbkL2BwTlMPVA5+g7371TJcfv+fjVhkBBnHcpbZPQ6KH8bkPxV4RrDhR2sKm4nHzB1FbwBVle3DRIh48XFzx1R+7p+1PoWrjXOFvNLquh/OQ0MuERqKC3pywlXzNEe+fnlZqaulebccDoQbULq3p3gf4p8vnoH9EXJxdccgNpBl/0NBAD0NgCBKf66zMKjR602YWa7a/ZVqwfeeMlq0rCtnLQYy7TYvsDg8FgNoPEmP+AyyuZnM2eq6uz/dXJe+FIFgYOVCmK/eaxFfS54ppnzVMaaPhibYbAzIiNKM4tbn0kfI/nXQYI+ccHtKU5BeHpCgga7WTtD7notVN25a405cBb+BlduUPrZpJECeYZ2VJMWEtTmeThnpK07cSTyIrVGvs/eCMxAyxUSl44+nYkBbRnNqmcnGCDUsGqziVccCOv2P5I2q0f5ZphAuAOnoxtKiaM38qYeb9it8oxAx+RfIxzNAlYOceSd7ai9TKJgkcON8EcRIw5fn4Asw7VTkYHeKWecxF7k4rJCUay6HHbCVcA/Q9ns3bkEvbfyNYO9zvmEqhyaRy1/Lu/esd24uG/9fvTSnX28Xn0/ZLn1n1PlOJjMBgMZr183P0fK/MOQ4d7ITSq3y0YX+HIk7xbP8zp/ANj5oOKpCKjZ+m9W18RS0R1NHxxbAZqedSQmySKNCu8DAJfiFOSsxp/ZkPvotFOwv5A+z+SDpjHpcrHEPJPDD9x3DUq8zgpCIwGjv0xbatQ8CdU1ml/cBKJpIAyHJntsVpvEqUpzJX88V4qWQHQdhHP/aBH8OsKpVyoH12MVnAAP9v8/ACQDac4apsGesFJJzSs350sLFPkRvoEVsoubWTBDqlcRinRzdxg7SZKM0Bqk9M/Nxeko/CEaTmV520eHKgCg8FgNoVNtz+inX+Bu0EJMEjAWPQS9ociMlmAQKZM8i7tz//SnQpvBIkGGr544yAchkVWhPgyCBwXkyIv8Wi0E11ETwCwb+Ri4DaO+qIDSsMth3vcY6ngpCA/DH+I/bEy8csvEzAv/IGck4JMQRD88V6QQylgsmL7Y8Gt3St4BEp5r9a9EK3gAH62+fkBIPuDEQonHXSdTJkg1PwQUZiVml7fT6/yMHeIqzTkfz3lp/wTrge3zW2q0l2KtFqbL+Gil2MwGMwnwObbH/QWAQn/H+A9+Ynu7INZYJbMD6rSd4jWX0QTFbQpk7m3sLYvpvOu4mEJ2R/CMVVy9ELLPUkZzU7miI3ksI1cmCQXEk9gIcRQswP16Xs1TvpXNHaCFN7TJoL8MPwh6y9Bl5besQALJWl/rMw7TqUnV9vYkRhA+ceevoRLKKgm4rE/YC1t42WVmnn2bGoOPkK0/pJ+ygE9uMgXHMDPNj8/gBm7MlNRQnphhXLTgR5ieMejgCXxfPQlvX2Y8tnP6uxTXntDTlqlldljBFVuO+9ENwwTOjxIHItMZQHjsiq7wjbJ/IvBYDCYjWML7A8A8n+aVaS+85x3BKP1sp3ZDLjktVZnlHH3n1ZmhIeKCMEpW3Wy0BGIPGLDYsGh2pZE72mgfD8Y7iOLR3zZasDXfzIraUc5+Zx9+UWjHe8i5P80Z5fQmyoHNK/D7rSg3jga98AUlmgTIcowHJp/ciF31znnPD1+ByZtdenR7I/3XvKQAu2ooGZ/Ot/9J8wOfyDnWTDLz8ny7BKzhyka9c7d0dozBndu8sf7GOyP1dDboZYc3lZZw1n7FBUct1bmlnH3n5blsgZovPZHHmvA0ftPi3TMHg5uOsjGzThkfsHs7qX8/+44ZRlbpoBVMWI81tAPt76i009ZrEwXx8iqjJKuF4yztZDffe1Uj2uI2MfuzAXMOlTl6Kh26O2TztrazidvwxYVBoPBYD6IrbE/ANz4Ly0tjcoa9XXXNGfPBDU/1n+pob6lk7ze2XKiQXeff/yEgZq+V7NLxY52UYjEf1FkV5wJn0pFo05a0p5q/XWTzvRoekEUJgZwVlWxNzPnWy3rLV4+/stJozN8HFSK4KtB7Te5JWdMFtKk7+wbemgsy/uqsrnnPyP2tlMwwbQiJXHTPfkbSdQVpSlgVtvsaPkk4BvqrK/RdJK95vZWg1HzVZIiNbv4O+sLyXUeyv/UXLm/jOjUay47poMww7BQirSiOoL8bdJ9k1AWpSVty6441Wb3ghQo/5/92rpKePTUrCcu9cAoNqDGLqNQO9uLlHr7y+eRHLZoSXcUP28wq8rK41ozadZf0PWN0JUGH6FT1bdcIckrLfUqHV2ZK94oBf/vf7nZhsM+sj/ylVqd1njDYiJqKs/0jKINGYJ0oMN4YA7e19YcgYeKQZl0Ftf0PKiGuqIsRVJqgRbN/Ezc+jYzOUmxq/TkeVgiqHK6mnDOe1zTQWDTHK67eEFDXCGtNzjHiQNe65G0tCNWL0djMRgMBvMBbJn9gcHEDX8+BoPBYDCfDtj+wCQu2P7AYDCYTxVsf2ASE+56UGvUBSAMBoPB/PPA9gcGg8FgMJitBtsfGAwGg8FgtppNtz+QK0kMBoPBYDCfCMwA/2Fshf3BfML888HSxGBEzLu7b43Ouq51udnokqvUvOPsd2fPVdYYRzhBrDCYTwJsf2w0wUmnUaNs1JktN4zatq6frC0Nt6K63ooNatLRWp7J9272zwXbH5jEgwr6Hhlb9WaLhTRc6mw/QzhmmV8YQrP2xnxeMKl13MKBev3osmmQ8Z2ICM54nk7875uB+nwDite4PNHTZvUF4QEu6CIPPG6w47Io8iUCOu9paGw8WnjI+lLSuw8Gk2hg+2NDgfHiD1ZFPMQvecmK5DVcf8aMz1qK7Q8MZpNYHjUeM3toP7bUn+YvGziO/xGL/9bmbuM1wXXcEmHZZyN03NDcDPNu7X4Fc8+CW3uw3j7DafvUoqvjhI2N0BwBhiZIJ54szYw9n8He7TD/DLD9sYGgkPSCCHkLDtVhbH8IwfYHJtEIjer3RprXhPW42cObRlh80Xu548JBRYVtmvlmPbdEWHxMHOlFEYi4UMsvvr/Uce4AE5yZZmnMfPSA+RkTKpMaJ4/oXEw8qTAwLNSn0j1gPhew/bGBzDnVu7epHDACW4R3Tx2jfhi5xqrruDU4eKtDZx3xhyjfz62lO1OK1d23f/xRX3v4yvf3em8P/KivOtzlWZobtTTkJ2cW1WvNlquamlMk7Sw8bH9QcyPdOsO9AStxrmtkZtp9t1O5N6X46h+LE7aq3CKV0T7Oz0Lige0PTKIBw2KnlxG3f/FIzR9QU/ZLvc/e2I+ncKYz13ELCxVwXSg2PhMulFCTP176/sWbAWVK2F1eYNLWcqr/hfe3YR9z9ZLHWEu45ul/ENTS+KBRmZdSSty8655ZmRvp0XfYHg7ajLqeYT81D/uTtEqiR38yP08YjBOD+Xhg+2MD4YdA4wAD2O6j50Wo927dvvqBWQq+rzChVoFhwQSSBSl8CYPLw/VeOuActTxqyCs0wjlexv5Y8TvP7kFWDuWzln8JQ/ZT878S+49Z//hXV8cvb4VvVIkItj8wiUfAN9heXZCpSNqW0/ijjxu0kpp+1NbtXqRgu+S18HXcQhMYNx9R2meY/xhCbx9dNbrnUfOnozy+9w2cys3KP1j6dX7196wRszJvbzpAvuQ39PD8B9xxsk/7O5os8bu1h+phHEeYoNr5xv/86XOpeFgYzEcB2x8biOT8x8LL0fFX/cciu0CgtXGsfzYQmS+NLKwA+yMf9juwv2BfgODnQv3oInvZrEOVy0R2BT+l0+HpQ28d6uyME/fXjqiXEGD7A5OwUH6XrqAYtjgGamnkSnnNJYvVatFXZ21rciwIbfz4b/G7iFJhJOqlp/ryOj2851J11m6VcCtrBNDuM4UmTdj++Lu/ejcb+Rm95FT3z3L7EwwmYcD2xwYitf+D+rNbNzC+kfbHpK0iM5+462J4PgPfukB/111TUFjbPynsGhMSbH9gEorQ6PVLzvBWUGAcVBs9S8x/wbG+yw/gPCUAtEE2kNA6buEgtj+WvH1dP8JJUADoBzJZG0ICbH9gPg2w/bGhwPMvBw6Rz5eZ/0Pzrp5u9zxcf9lz1gm3jFGLzrN72PWXqPaH3PrL8qT1yB5mfnXZ9+MPcCfa0tOrup/fTN2rzVM73v4DpkCw/YFJJEBjVNb2v6YNBmp+qPXEHR9jyIdmH1zt9rATG7BhFiE7Yx23cAG3H6vu/5v5D6Qw+3Nb9zO23wDWSV6eeHcIw5rrL6o96iH0+HdO9dfs+gu2PzAJB7Y/NpqI/4+bXUaD2fEKNfqQf+RGk6bTYunUNN2A+09nfuuG+8UuPnwx7u6uz04pJR56vO7ryuzMUmJg3P+YSN1VobXYHXf0jW12X2CVmmYvG18KvhpsbWjs7LWYDW39f/jclpay7Fztb0vUK1tVZmbFxT63pIOABALbH5hEYuYBcbbTqNWablrJToKwgBYKvw76XFaidPs3xmdoAzhog7eJ0pSMUuKWe8YX/y284T802lHC+AUJoHtyy4zDfnhPcMZ9iyjNAG39tnRDXhzV12rdvLUbtj9Bt1BzI11nNcZei/FcU9dTP7Uw/vBiaUqe0viDIA8YzMcF2x8Jyaf+voLtD8znzvvftQcvj9K+Q+JieVh/+Mp6bsRgEgxsfyQg7PtK928zn2gng+0PzGdP6K1D12xndonETGjWrj3rSPQJTgwmFrD9gfkIYGliMMiRj+n+ZOzuSqng5EBH91O0TIPB/OPB9gfmI4ClicFgMJ852P7AfASwNDEYDOYz559kf2AwGAwGg/lkYAb4D2Mr7A/mE+afj5Q0l30ObWlmrtApJM38oIpxYM+FCvqGjGeON+pMFtKo1Xb/dPt8g/Wx++4VZXZqtvKyFXLT1HIoK412r7ImwelHpo5B+sg0B2rKXv8Nx7slh+CrwQ7To2np1KWVlpobIQmN4brFdLFJqzvTeDsSHERcTGqaU5ybZu2J6sabo4wL7ZB/5KZGYyBhQhf0Z871SRyYCvicpjPKUzpzL2nUabvu3m5pFl0WnHHf1VfvScqu72YOfFJLY7fqc/Or9fbxpbj2GkhJpG/QWlZQedFksXbTx0pvgoJc/Da7zDoJHmxUZiflKY03rVYLqW+sVHYOcePRcxFHq0dA5zpMtHoBIDOy0eoBW9Ol0JGeGP8+MRJ3SQO+QdPlR4wzEjFrlzSKhn8A8hn+AOLJqrjgFKNymVV0DGHQvvqI0p3lRJ/7U93sHwvU9KPLHYO8AAIQ6Ms/P3xKnKdjQZ/1u1Ki17F2rDHQvfxgVB6S7Ng3qg1uekvems4CszXISJN1vyZkZd5+PCUpX+jzYPphU+ExqzfsdPIFWbYTeX4UuI985zx73j6/Agb+0b4Ovbmrvaa0yiyxiY/y3TmheyLq2KhFty5XQcfjkGLxiS7ie4qHVDGp9+5LB/XDyNMUFfT2lJWHg5NJF5NfnPde8nB61W34OO4BTlj2WtGB7eD0YHNhldXLdCvoccmS57phWKJdKcdhLdGsPLt6+q7obEbIP3pLpzfdaD9WXNXFeLzgIC2RnluXzz1E0dL8LiKbHYln7OdJGC2W5x6UWn7R9fXeC0/mxUNWLNHqxchFq4dsVZcS9gwWI+sr6ZxLR9h8rAMzPmuVdC0NXyfRM7w+4suqdMF9t058U56bcdLORKuYsIKaQ59EBN74Zjcu+/GmtrFPl4easJ3oEEVUBj3bv7W52zgC5OoY0GoVLQX/6KpOv3qjfbW4anUEieWta7VVv2qxrBJNq0Mw9HPkYgEb1QY3vSVvVWeB2QpkpClnf4CxSqs/lbuL8fpKM+ci8vnfUAuO5sM8+4MKvvn7TTA0228CL/3v3Yaj5DhsZGDk3lUoGuZBgo2kl5MezbKn95L+woGdFbZJ5hshwCZoJCQGDMligqb4bS5jf4AMeq3EHbbvkywmgGdOQdcw9IANRu5cA+sHAiRrEE5sLD4mdgqKOetQNUj7lVl5ZszbFY6ItuIhzwujo8F60x2lQ8b73dpCUT5lJEL2XDHSr1Bc+2PBrTfBT0L35CCHOfvNz4WuP+OIVs9HOlo9ZKu6lDjtj/WWlPL2HiEeS04LrFHStTVcwIS1QrtWeWIQzTqIM6vSBQf2neWJozFvp2ZoHtaznP1BBacGGmv7ZEyTeIk3tY19ehSAja47QneMPBZf9F7uuHBQUWGDJgSCo2OsSfF+VXd0lVZXt3Z1l3b1fWhVf2yVzjY1vlqhXw1h+wOTUMhIEwy0O4vVptsDd/VV35k9rL7OPzx/bdTvbM7gxtYJONVf7BTG6PKPOp6+4wzYQO/1YGyjZsb+fPf+rf1E+n4YLlgwojMEnhDFRvhGziM49eO13hdeuzJbeD2HFY+xmHgiXjaQLOaKl/w6Jbe63WJ3ef1UaOHdPNOTSxYTws0tsKXqttGlWBkjv96RXd1mtf824Q9RC3NzvOlTKuDUfCGMfLbif+p86l/2j1h1HbcGB2916KzsNMaSx1jEBGQG5kVbW2QuJMzbAWV6qXkMFBSOqUmCsPLRJELDtT9YhPbH8gRZnlRM8qcsYo9WL0YcrZ5BUjqU/2lX4xk92WvWtVmBBlKCWPb0KuF2Vktrr9ju9N7+8Ud97WHz6NLiqKU2P3lHcb3OZDGdrWnoQStlEfsDJN5NdN4btBBNN0bmX7vvXFbm7Cg2jixO2aq2F6uMD8aXVtZfUmBBFl9wBXgVRxO184xJw/nEYH/EJJp4iTur0gUH9od1Aq4NZZTo4Qt72P4I+Ud6CcOdQevFpq6n//t29AeiNCVbabT23RU6ooX+rBsb20mLSdf6vWcpKGhQ9KJbSrG6m9WN//dOkBq15LF19Ny90ahiOzpemn/4huWfLrh3ftTSkJ9WSfToT+bnqRxveGoGNdDv6bvW81N3Y223R2I5dd5F1IriA8Blrku9z97Yj6dwm3lEx1iT4u2qMn3VPAZ/9FlXk0pXfaFV477VenJ1Org6aVs961ilsP2BSShkpAkG2l2VtldIXyt3aN1oYFyZt1++BprH4pA6oyDyNg/HLblpWJBOBtowYVIX1Uh0f/ODqgx6HI1AjZu/UtoFwxT19lGb8fdFyYGTy7xdeUAwZEJkign3ZJwsylKAn1O/anbQS6oyxYSA4mxHEQefOPuNjfV6dmcA2mxxsiQTJpRe0Pwzv5dCJoJUpmHPy+wygcsu+2A0IvS9lyxJqbZNBVffuy+3/Rp1gf2NQ5UnnKWIJhGaWOwPyWzHGK1eEsloKRAJ6cC9BV8hE2pxVL9/h9Y1LY5lz9PSCsZiA6VA+grzwhhPC6P6rwuNo8voMlSgWaf6AEocfFP9Jay90PyTi/urLH/83tvBbFP5kJLO2JW1KGiUEBk9hMSq4TzWtD9izHB8rCOr0gVH9gda56pNh6G1vIz94R9S7zkN7XXKay2vAP0DzL7AyEbAFpR5Cl4ZGtbvzr/4U5+oQcnoRjg16tWd89974aPIA4esk+ADP02te0Hu6eJ76XpWO9/4nz997p8WqFloqv987zgFp2mPHrKKZ9b+NH/VKHzZoKYftXW7F1HgIF5dh3UMJC40KRyq1f3mVZCQ37Nan7Oaume13LiK1FHiYpoomhkXG5NKFDYqo5hEQEaaoGen119g62XVfsZ+vJq4abVajar8tMj0vuTb9pJ39OUCSgdNGFBvXYQGjW3v596xU/DUO7eurmngL0H/BVqaKKaof0RfXaPvsVp79NV7tqkcaKsVFZz6qTHvPO9SqZsBayhtcHrE2pizm+65ZIoJYYuzGpj+/VrV/uZB4XbXwMyIVZXzJd9qkZz/oJZejj6x1oqiMSNLjxonSzJLyBcLrqs6Z3jSQkzI7+6oavpRuFstmkRoYrY/Cs386WBwY0zR6ql5x9nvzp6rrDGORJbDZIQjJZ3Z/mre/hipWLKSWgpKgT7B/pqtW/h5t340xF624FBtYxIHP6XDpECOpx2N+zLqf6RNwDhKOvOgWXnhmqbu5MArduiQuhchr4cxazjQnPFHfWhHt9V6WZl3COkqQPx2Lpnh0Lzj4nfn1ZWHro74uUPdgsd2iRBjdIp2g0pllXr9oFl18drZmpM/+vgDKI10wRn7A67mmEt2lZE/3YD2B7XgaNrGyA7U5JfV/X9zpckhNMuNZy74l2lQEuHNeamFnhn3HTKPzc88u179xVHb9Ht+mhCZp4vvpU0bVm9FajbtMe77ElhTM8+6qr/gLKYwgIuEzYNaGrlSXnMJClBfncXrQ8I6BrSaZ1L43atVTavwsdTqSPdqx8+rQ12r+WmrjQOroOjY/sAkEDLSlOrZ4aoEPR1NLfLWJsS7DcAAatXBd8fwgA2G2z9eLlGrs3Z9Hz2KBHz2Kzq70PgAiJohFfTevfwjfLug88MsN/g9D+7qj27nt1iJNgyRKiZICi4JMf+Bl4/CI/Bf2WICwsWhP28vNP8Jfwt3oxDw3ny4tOceeaSsFFJJOKal9n8Exrs7rndXS9sfq8EpW3VKidak62KfvuQh61GCpWWE4y38BrzZPdDpHoi2ygOiSIQGdF5r2h+S+z/EI6tktPrliZ42kBTsjTkdt4xwpKSzqfbHtK1C8SXR/6uLxkPHgvOPmOsKco/3M2WJsaQgzW9hgFzw3MhalfheBpnmFo+G84g+/yGVYeplT/NtHwVymM/WZ1zIZBUUP8/oWQFPqYpj4ifScMBA21GQkZd/7HvfamjadlSRT/Qz4vndMxOe/5h+ZP0VKT/NB9ofKDVqbsTcVG/4wTU+0AJNh4C8/SF4Osi14F46aVZvRWq27H9qrlcZ+v89bm/mtgsGcK+geQTH+i4/YPaeg8zzmmdYx4AUIiZF0Leq0yHjY3V1xbP6jZ6e9lgNvlqtzFlFTQDbH5iEQUaa4p6dXZWg4a9NoNMW1eQYu1BAzbquWdxwmiPcTdOEZu0XdTDZiPFBTdgMgllun7WcfiWloaYetFk8bJQv2MBhT8f+I2ixcay/gKIdq7S+ZO5eHtYfvOR+H4pSTH5xZuzKzC/UzgDlf+0yllf2vWLsgIVR/TG+qQFA518OkWNsKah517Vu9+LsQP2es05YUcDWObuHXX+BF0zZKlPS8trdXBuCA8f4oF7eNAwKl6tkJUIDOq/o9gcYZqxVhcTQW9oeCgMrLYZo9Qtu7cF6IFa2x0fEu/5SWENH1ade3up1+cSx7CW0lD/GyK2/wFn9EkZG1F8/9rkX4fh3Q/fg1VT/8bzGn9/Cu2IsKSDkn3j60KCsuPGMFVac6y9xaTiPaPaHdIaDv2t3nbTPv4/UWFzIZ5XyT7gfXq6tuO6J2OsRpAvONdypWacmj7ZmqElr+R7G7qd8g32uuZBbuwP+NNGnt0d6BnjTQP0OJW21U94fe+7dFDUoCd3gpjY9qt9N6wmcNaywuu+2d17mptnrmpd7ekh0r77PErE/hGr2y7/0xcVQ/9GEaGmP+47pDm9H8IS1/AT7BgIIzT642u1hmzCs6yLO7hCJ9ZeI8UGt3jSsvh1bPWpg7I/VwGpr9eokrI1P0P6I6v9A6EqBPoWclwR39Fgt5ov11eqeURQjG9Sbf5jUnDOQvaaLzVq9ppF5V+YCqlDs2EB0GTXtvtNenfVFtvI6G+p6Yez2ydycGr19TLjDJzqROP43jNq2rp+sLQ23fD5rWfa3F803rTfpoN7dVlD2yoIy6xi3dFbrdb2qWmn4ReI8d3/LWef0R/e0ISVNIKDryuzMUmLghdeFgomr/o+2uTo7r/qqC03G0hd8kVXdfod1UxHJlaXbqOt2+AJQBPxcmdsbitIqrb7lpT+uFieDJ9NwGxUiNKwv6UC+CkCyLitRtr3M9AztzaRmUBB1FN0c5kTUO4dGO4r57/004DHMpwhBX9+5M50dhNZIAjE1arpGXo3ZDbLFjBTnCproDk7116cDKV/XturOnTxj6CR0RtJC6s80wkjr9CO4hP1/3LR0derMj5BKwJ1uTZpOi6VTw+xQY6Fe99cc0o+GV0z4LI0Yi9Po6ktKSmEHQi5SEqF/mHHfhdtx0pKL1Net9+nWwTpjCPv/OF5WfVnS/0c80eqXxsxHD5jDo7JEtHoaUAbmE4fI/lMDrU6CWPZiLb348MW4u7s+G+Tg4TgYb1MzK7XWnxz3Ohpb7aC22cj4F8GPQd/D1trTnZabZn1n/4uX7p5zZVlfad3zwOyrStlVoYUx+mMuKbA/hp/YzpUfZ5cegAIXt4laLkRU0rg1nI+c/bGWaIIec/kRs0dGu6RZI6vA/nj65HtNuXrAJ2Ezi0UMbu8jyneWEn2MtiBjooo+ZhLwDepqGy9bLGZ92/1xYO4sjZoPVaiv6gwPmekAlvBeUbPhKmhTwgYVETpHN5a4qb0dIkqOaH/46V73VW3doWrN5Ttjfn6ask8X3XtOozsF45Uaf0DNCtQYR83G//et82JJhe4H+91u08W6kmqN4V74hQQBGsgxxp8KquvS7d8Yn6GREXQ+sK7BQAM1E14Q0THWpFhaNRaDemb+8oyrK9TqaO9q40V4/vZi0+oDWLOfpP0Rzf8BeOkRu1IAtRDZtA9326XXotPMfrcWCIBuFUtesrpcNEMo72pCDEgtP4Wzk3HF030a7lbjQflH+nQG8w1dTfF35hHGDIpAvR5sOlhlHWfLA3JVkVxq/WvUfI5+a4dmKbuxi5m655UOaNULc8Ve4ld0wIyFemU73o7OIobf4QRI1luU4gtmGmL1tLFRarehcNUgKsLeGbzpNkjemJDF/GcSa7T6wKSt5VT/C+9vw8yoLB+tfjOkA9tlpA2ui5hKuuDWHtWBRgqfR7/4UsujVw6Hz3Xzibuka9gfk7a6DnpzeBwEvbYmov/Vy99+k9yqsR6Cbt1+HbD7gdUnvayDG2AMcD0SRYerY7ImhRSfpP3hi+L/QNKVAn+Ehk0X9BX0IHogPH5QPhshnNiI4mpCghWPMS/iymnJc+2y6Cij3607hVxNIL9PwvOW1KKrdafgywWHCjzP1W1kDFWO/RFy69tBXyGwP9AtXxzknvKgJvvqYHMFyNkfW+NpI0H7Bert4NnmB+HFCGlW0CtCailhddH9KDX7oPnsIJo8F4K7v40jlmj1730Dp3Kz8g+Wfp1f/T1qCNGi1W+8dJbGH4LXxYgb2fURS0lDfrepQd15U3ei1vQUti5qyt6scwjXrRjiK6lIwzeAlVcDxwuy8r8uPVhULTG7vE4o/+/GhmbjTV19bRd/WysDboAxQU07zmpZb2zy8HQM2x9R/B9Iu1LgjdDUbH/NNnp4DnjJwynZNe1Wu2vCT1GL7+Y4Qy0gimMDoXsA9BN05ZSJTujBAbjtLO38kcuUXclusuOtf9PMOdW72b3oYd49dYxGBMi1PxhE9gf1kizejlb+aN57yVPwnQkC7IaP52kjcfuFkH/E0nHfK/viJybovd9h4S1hcMDd30YC2tqGRqtPXOnEXdLA5H1Tt3galeWz1UPcAGMEugzpGJgUrtdzEegY6PA/d//raLFZwv8Bu2lRuI8PjdD0DmfnD8ZGlS4c6QNutjhZlJmSlKRILSAcgvON0ESQPMUO3eOL3AMAwEh/KAUe/qbeu7vaoh1lXJl3nMpghuowYMzmH7oWE4v9IUiHGifrzKx/LfDTR/O0AfhM+gXc/SUyn490Pls9xA0wwdkoAW26mKNmVOD/QM6VQniEpoLTLmNVadOgIGITFZx5alUV7OatNchMAEDHBi+kjudB4OaS5EOkd9rVZkT7oqWh/C5d1bkB4YY7yfmPhZej4f0Xsdsf7FlNYFx4TNWRY43gJ9Eefrl6ky0+yCBIB01vxONpA/CZ9Au4+0tkPh/pfLZ6iBtggrNRAtp0MUtkVOz/gP5X1pUCd4RGnxk3Rzz//9S4ubDUNMBzeyDn2OD/ytkfcKdn5a6Sy0bdZfYoY8jD880ACP5l112xS+z2l9r/Qf3Zrfs5so4Ti/3B2/+xMGrQcIKbSNkfsvW2wZ42AECaGAwGg/nMYYaED+Oj2B/WQxL+D9hFBBreUgJ3hEYHPb7QOAMh/+vHxvI66yt6nKaWRy8fFMx/gG+lHRsEZyXcA9AgV06pRe2R1R8+EeNjeeKmSeT+9vVg04FD5HN2T3Jo3tXT7eZsI1nb/ljyWo8Vah4x+yLf/66r66Pd9yDE9keUepMrPkgubH/QxOZpQ1KanyKfSTH/oXw+0vls9RA3wARnowS06WKWyKjvdqPQ/8HCuKwrhcnpsIeMu+jg+NS92vS9SuM1olVLnGzu7LyoNd6wku2NjXyPCAwyjg2E7gHQtQi4v3Vf+HiOAP8fxtKIK4qw2x8uEf8fN7uMBrOD3aoCC3Xfel1dlJxWpDZZUVnQl3z/H/UV1fqw/w9q0dV+PHIGmK6Wj+dpIxa1E5/ghVWtadR3Q1mTz2CK0NtKV7uqNIfd4wKdNzQR5M8DZPPZLrRVSvxNhOArh7EdKM8N4tsSzQBdV6z7h259s9k1HxI/QvIuOdYu5iYCVcIMsx52pC3+RhRPX1Tt1ARZjKRIk1yO4k0wsF4QYKu5CUNbwS3PXzCXApKrrJOLwodKXBPD0b9NADyc+SSHWNbUG1eXTm++aTG2NhmGYNuAbwKoIKmF9eEd6BDwAqCspE1zseqGQR1IMznwM0kwHYhY5cS3yz5UGnAh8ylWRKoiltorj0iOS0J9iAA6kEdG0FVbu4iKwxr4ZiLWxoDPYdaBTvgGUVHSgt7N/C4iG6Wenl/fi4L5xQe4k/mUGFBvXV2terOl10g0G4b+htIWfiNqUzzCv+qbja55KqwIitT8E6w7K+E14ocmDhsloE0Xc6Jp0j+Kd85mNYwrljCsJU1KdIJ3ft5xakdNPzwcC7rCksPsulJ4/gYQGDNXlKMAS5TPWv6leWxF/A26CQHdCKafcsyvoA0ue7XuhdXl5+ThOtK7hHwIFsFvINxHSN0lz8dXWtb3YgTuN8J4+r/5RQenA05TJ3M0fXGs7+odzh4kuLmY8di4PEFWwvNcgX91dNLuAajlMVvbHdbNK/ehctdsOWtKRyzr0KjxGDPbFxg3q6DXpqBLK+GLiwp6b9VkZaCpQbjHXEp1IStj5i/LrT74ExPzDH3NVTmp26UfKss69TC61MTfiPUB/koD4/mlqwbnaS+c7I533iNg3LVsleMN2gC3B13id2mNcZRTRIKNGqASmplN+tSf5ooroyHRN2+j1CGoZ/JwVa83SEFXrVl0TDujljcLLr5G/FB0YWKwUQLadDEnmCb9o5gfPNX0QHQG+GOyljRDohO8oxzX3eCtaB97rpjTU8NXtH3MmhR8LygnveAVjf8N1zs15f/r5RtwI9wsnHHSPhtcdDbvqL43NfP830xsDhqe/SG6K1pr/vhKG93+EMbT7xkWVrsXuXWBQ9/SHxbdXd7JZFijbFLwczGo3VnfGzSCLo126+5HjvNxHxqUuWbLWVs6IlmHPMZ9ucdJ91QQetNCvhAkTYHgyzsd5I0z+5D9AV/i2dJzVRcAxphyqZ+4Kid1+9bbH2Kpib6R0AeObCn/5MsZcP17L3k4I+zyn6efIf9f3hk4yTROluShtexPzP5Y8hgP5taT7ulAcPJuE3QaJPxm+kmUOnznVH9Z3e+d8Tz1wJqEiOwP8TXih6KvE4ONEtCmiznBNOkfBLXg0J6GbxUJRBzSZE7wznvJQ6lqJ2pSMAZKuJFGemrYXtk9MfRnp134Da+twrtdd65rq2oNw3MU9Cm5NznnmOnJ5Nux7xtrTewyHN/+APDuisbHV9ro9kcEUTx9wcHp5VHjCYsgdDcclVM1zgD4Fu2miiS76DESPZHNzpIPFV2z5cQkHYGsqTmP9USOIm1PTpWRjpERdOkqCcvAkPOH9sbzD9F63LLvfvcd7wzrlBOexpdSXYDAtgh/5qqc1O0SD43GOvUwJqlFvpHXBxoK1iV5oarSOBxeSRE+IuBz/UBqaysNbrSo5HfpGgjLT06nTdfYPiixVX8NEm3UoPzPrPV7Fam7cspNdDgbwTfR6hDGg0nNqTE9mZoZ69PUGuFqXdClryR6Bpy//KBTnx98FZS6RvzQxGGjBLTpYk40TcJ8CLFKk3OCl/I/NdZq+sZmpp6YanJS2RncD7M/IIHpoYsl5ddG/HNgAGAd58851XtL6JUIsf0BCd/1T57/YBDF0xcenKYWncRB9iB3BGpuxHiysc/zduqxqSYvOTypvjikPthF1x2D+KHia7acmKUTkTV000Rc/dnt6KovTMs5wzs5j6bf1M531NTgtbsvg9CeYJyCy6guIBb7I8rtkYcy/8qwTj2MRWrcb+T0gUvw9RBxuByNixAJbaSC04+IkiNG3m6t5QnyUAaz0z8OEmzUCPlHeomOAfdQV31+Zk4jaHGib5bfydYh7MEylfRe/oBTnXqIc54R7dPKaHbOPxZd8/9ED/2orY7PRglo08WcYJqE+SBik6b4BG8AzSt6+6sL0ToxgNNTx7n+Qvn/ejaBukF4444S8g8vbzJcbjAQ3BVtDP34Sru2/QHeSgXx9MXVPutQfSl0AMNABeFy1d9T/XXb4eo+/GbB0ZQu8F4jeqjENVvOmtIRyXr0D+MJNlBD4JW1Jkf/eNT4NesuaMJauru6f9ihqSNuWKzWbqI0k40aCK8XqS4glvUXGu7tf3mED43Ey5VknXq4ttQkvhHpA03IP/HnBDLW4UipYMdO7iMo/8Szv1B1w2pRgKb1zLh3N+0FAFZIxLtBzCTWqLHyzPgNG4oo+NJaWar/vy7hNzC8hkwdCvu3bOLXfxn3sl6vQE3CuP8vhNf867HUIxKFjRLQpos5sTQJ82HEIE3hCd6QW5uFDl9QU7ZvvzKyE4ncnjq2/afBNy9hL7c4qi9UVNigJxbYsLfvNz8Pjpn3l9ALrjN2JRhxRSaO1F2cDWJCPr7SCocQwTcc44OJpy91cBrGE8jjTB0FZl5OwnECiuRbeHqFemX7tpJZj4DrzUWCZ4qyIXXNlrOWdMSyfvrcfMrA2B9UwNVWbR2fcxivom/gebftdDxLmsj8h4TqMkoYy/5T8e2hedmHSrNOPVxbavxvJPQBDKXev4DZAfeWbq+wTYKrkP3B+iXiPALu9lUctcHQ8Mj+2G8ee/dIdxVtcYVhmfdV2bj7SWIisUaNlefmo0b2ROS8q/W0dWJE+I33sWwdwv7tcAltoc7blTtOOeanHbob6PbQbL9ye9VtHyW65t0z4SM+0nEzSTZKQJsu5sTSJMyHsZY0KfEJXuqt06DRk6RB03iFWQmGB4AtRnh+mLjZ92h8iYKnZ9c4fxt2eI8OBNKHt9uPVzTQp/v8HssZJWGOhLMXPmJF6i5ZQNaZTx+BIDynbVTC2N83b6MwDaJvhPH0/7MgeXAajCs79kVO+oS3hlAzTgOhJ7sNGrU+HMoAbqPZx5k2FmcDILjm4wBKyHySRkJDKP9wb/OZi6abFtPFJh3aeBH864FB20l26xtPdzwJu/9ZGHdcVxdtp+c/VoSqy4m6IHn+VqDVYs2Xfqgsa5VUTIxS438joQ/hfUUBn8NEaI2k9Xq78kgDPDMsegQ87Uw7QWhTVjSh06QB3wMj0XkdtEdVx6/INUB8xF/wTSXkH7U0N140WW6aLjbrHgArX/RNtDoE9t4flobjxA0gdw3qzYCKPjQQV+BhXdXVJ/SmeeE14ocmEBsloE0Xc4JpEuaD+EykiZU2kfl8pPPZ6iFugAnORglo08WMNelT4jORJlbaRObzkc5nq4e4ASY4GyWgTRcz1qRPic9EmlhpE5nPRzqfrR7iBpjgbJSANl3MWJM+JT4TaWKlTWQ+H+l8tnqIG2CCs1EC2nQxg4xiMBgMBoP5ZGAG+A9jK+wP5hPmn88/WZrco7lrgJV202EOIkY5BC3LP1s68RQ8zpLGoeExszJvP7GD5xFkQ1gjq7gBbj4fpC0bJaBNFzPWpE8JKWku+xza0sxcjp8JDvODqn20JyIuVCQqL2nUart/un2+wfpYEJXX1HIoK43ntUCe4PQjU0fkKCkLNWWv/4bx2wP6/WxOToKvBjtMj6alU49Jaam5EZLQGK7DI51a3ZnG2z7mB4lSUzPuu0ZldlKe0njTajFp679rjIQ/DflHbmo0BhImdEF/5lwfHXSKSySo8g2jtq3rJ2tLw63I4xiC4CH66j1J2fXdbPTjpbFb9bn51Xr7OCcgp3xmQAq8aMyRaLrcW6wWUt9YqewckvWrLS0OanagPt+AwmiBUe1kNuOJCwD0YbDj8iM602uyNV0K5fu5tXQn323GWlCvH102id2Nyxc84Bs0XX70Wq7ca5c0ioZ/AJwMg1GqlPGU9YHEk9WYRcxqbBrjTAUoah9RvrOU6GOawOdJPP1h1J5Qjo1qg5vekrems8BsDTLSnLCW5kvZHygUQlK+oP+iph82FR6zhiOyBl+QZTuRxyc6dhp0/YR45zx73g7eFMUx/flQvjsndE9Qq+JCLbp1uQradzsVcF6otr3i3br4RHfiDnQhJSIGpaXeuy8d1DNxRIPenrJyK2sQSJcaumxKqmADWo6TJdmMX6b3v2sPXmYdHYKqqGWuCUO9Hmw6WGUdZ79d8pIVyaXhx3EBudLtSjkOK41m5dnV03clHE3IZQZ50EoKJw6j6dKhTfm3rFLLL7q+3nvhyTzHqQSLjDjm3dr9CmY8n3M2n+YHdqYWXR0nYnNUtVVdCs+ZWAws+2yEzjXH/BchesHnXDpCzhHZWiVdS8PXCSfDAWdztW1tRyVrE19W4xExENOpbyr2cmLj2YhIH8InHHtvQ4g3tY19ujxx94fyPaEcG9UGN70lb1VngdkKZKQpZ3/M2M9r9adyd0Ve+ABzLiKf/w214Gg+zLM/KBS+NTTbb+rzBUUx/QUPAgk2ckMqMCx7ei/pLxzYSXtvlOK9l2wkJAaMWJQW9Hrf5jL2B8iv10rcYQ0CyVILxm/oJ54Z5sH3uQbW0SFI1sCf/wADc+vOXfyXxQWH6rCk/QENDmPeLiaQBPjPQ55nP/OQy4zA/oASYeN68m4BzDpUOVJuZCXFAeyV7y91nDvAOMqUAphBR3SuxbV7wa3qUuK0PxYfE0d6BaH+Yik45e09QjwWjRaQNUq6toYLmLBWrBl+NwZJrYM4sxqPiIGY9JaRnxqz9mmcyAKRtT8CU/ZztXKmSdzEm9rGPj0K6+gPZXtCOTaqDW56S96qzgKzFchIE4xSO4vVptsDd/VV35k9rH0w//D8tVG/szmDO3wGnOovdgqDkvhHHU/fcewP2KeAoY6aGfvz3XtRTH9+Gw48IYqNHuEwGJz68VrvC69dmS28nsOKx1hMPBG/ksSitCte8uuU3Op2i93l9VOhhXfzTMcuWWoAd/yGfql3M4P3yhj59Y7s6jar/bcJf4hamJvjBZqac6p3bxOGXHn31DHqhws3Vl3HrcHBWx06KxtRD7rWTq6k31n97ra2yFwIF7nMCOwP2fkPAHS2ncSP1Q6RFAc1+eOl71+8GVCmcFMQAHJeS7jW3mkgKR3oMLfxjJ7sNevarEADqbmRHn2H7eGgzaiDq0v0KuF2Vktrr9ju9N7+8Ud97WHz6NLiqKU2P3lHcb3OZDGdrWnoQe5xI/YHSLyb6Lw3aCGabozMv3bfuazM2VFsHFmcslVtL1YZH4wvrQRcF4qNz4R1HUvBgclYfMEFQ6cKiaqHMWk4nxjsj5gkFS9xZzWeUYPuKwKz9pMZBR0jS1TE/gA60K0z3BuwEue6Rt68Hb1LwMg+l63W+27a5ShLnMoDuri5d8LU/J6+az0/dTfWdnvotU7oIVfTqL9uMbe1Wod98k9fXXrW19H70w11LVBF8C/SxrSj53v0x/MzTjnml2EgOsOdQetFxtOu4HoB6+oP5XpCOeIRUDQ2JpUobFRGMYmAjDSBWbCrEs7mgb6gkvXrvDJvv3zNswQjbWYURCYt4DAmGc8WANLJQE3UpC6qkej+BMHlEdS4+Ssm+G0E6u2jNuPvi7xwdFLM25UHRCNorEob8DlNJ4uyFODq1K+aHfQqvkypAbDgXxL9v7pcQ/3GM/W6n9nQcWg3zMmSTJhQekHzz/yFa1An7AwEH7hIz+wygcsu+9j5ZxgKPKUaTvK/d19u+1XyxVo+M8j+yCf6XS7Xk4c3GsojC15C+wNdKcqZlDhCbx9dNbrnmcBa0qIHgKprOsAEcouGhHTgwvZXyKhdHNXv36F1Tdsb9zHzT3639lC9HdhjXC2tYEw0UCikrzBrjC21MKr/utA4uowuQ+WbdaoPoMTBN9VfQkMtNP/k4v4qyx+/93Ywu1YC4+Yj4WknlhgLPmNX1nIjLIaJooexajiPNe2PGDMcH+vIamwNkAYIBb6rwLhHVXug4Bj7Y8XvPLsHGe5sDCmQASayD4+4lYfu4nipUVP953vHKTiRcPQQDFwVAvZQJno6jI8Db5B5OrAM7lzu9b6H838HaukgL7D6M5qdC++e//uF/3+H1HtOOxYoOMkKIw0tiK/nss7+UKYnlCMeAUVjY1KJwkZlFJMIyEgTNE56/SXcZQNm7MeriZtWq9Woyk+LLEZIzn8seUdfgqYK0kHTG9RbF6FBQ937uXfsjLwwuDwDaKuZwhblH9FX1+h7rNYeffUe0eQBB6mbAfEpbXB6xNqYwwT8lCk1IDx+B6d+N9bsb3oo2iAXmBmxqnLYwJgMkvMfCy9Hx1/1H4vsAgGJwyiayPCD+zkyS8gXC66rOrkI77KZgRJk5z9C/jFbY8l3ZjqiuqT9UWhGC2MRJGp06am+vE5vsVotl6qzdgtFz0FGGkIkpDPbX53Mzdvf/dW72b4e5hOFYJXSUlAo9An2+Gxlws+79aMh9rIFh2obkzj4KZ2O5kpNOxr3ZdT/yOw5gD17qXDAjrXgUvci5PUwZg1fpZbGH/XB3cSAy8q8Q0g5AX1sgF8OMUsKaKDHdokQY3SKor3EntUI8TRAICZkf6A9SSXbKsghEtkfsw5VLqMDUGygdcCVXwkLYJ3Kw7MnQh7jPmDiBGaedVV/AWMfchOhkbM/ljzG0i/NnsDM067qXHpxhKONMFLxNuYzSOHL6v6X4uu5gHvX0x9K3RaF+HpIeTYmlShsVEYxiYCMNKV6drgMQU9HU4u8xQjx/g8wYlp18N2RtT9Ap/nyj5dL1OqsXd9Ht1hxcHkGUcOhgt67l3+cRA+D+WFHUyo49VNj3nleG5NpdTEobbjXQ1B/mguPwH9lS80fv+HnA+ZxNJHDW64Gr9GHS3vukUfKSiGVhGNKYv8H9We3bmBczv4ANoWtOqVEa9J18e7iIpcZXo0B2IimoEjcWyDS+z9ENbrk7ev6kdlxGZbvKjXvOPvd2XOVNcaRyKpzjH2ghHQ21f6YtlUo6LkihIeePfePmOsKco/3M0UT2xAyBZ950Ky8cE1Td3LgFVt18dof8Wg4j+jzH5IZDs07Ln53Xl156OqIXyDqWJDJKvX6QbPq4rWzNSd/9EmlGs+oAZINt0Qw0JZk5H91DOZ80laRmU/cZaTmej4TZC2At79aH8HoyAwfaH+g1Cj/U3O9ytD/73F7M1IkeftD8HS4itpdX9/R7xqxtzAGCkcbQ9O2owp6PhLyu2dmUXw9F1EjktMWPjG2PZZ4BBSNjUklChuVUUwiICNNceNklyFo+IsR6PxLNTnGrgxQs65rFjec5oh004jQrP2iDiYrFVw+jM9aTr+S0lBTD9osbJR/1JLz0Gqo3/Pgrv7odn4bW//6CyjpsUrrSyax5WH9wUvu96EopeaN3+C5KbvVzjnKP/Xa03Oosu8Vs/yxMKo/xp//ACV6Pdh04BD5nJ1pDc27errd83D9Zc9ZJ6w3YOuc3RPe/w/rwFaZkpbX7uYaeTzkMuMP8HsokJ8vk1EQeb79ATo1a1UhMfSWtng48MVBzf7c1v2MzTnogvPy4CaJ5YmeNpAUp58FfOD6S2FNP1oCo17e6nX57Ko96iGkYe+c6q/ZKfSo9ofc+guc9y5hhEL99WOfexHYxyM3dA9eTfUfz2v8+S28C+pDdf/f8BqETMHBZd/CD+C5ka0zca6/xKXhPKLZH9IZpl72NN/2UezYGS9yWQXFhx+ARKriXXgSAao08iZAzQ9pdqajrC5PWo/sYd5zln0//uBa9Lu1X8KffD/oOZJar/IscFIbH9UXF0PVpQJOzRelPe47nZ0m5Y6aftQk33tv3XIFuNdznh4a1u8+jCphzqneW2oduqP/0cdpF9SktXwP8/pB+Qb7/jUovp5rzggaoKwIBHzG6y9R/R8IXSnwXBRYzBfrq9Uo4jOE8g+TmnMGstd0sVmr1zQyr85cpDxPiC+jpt132quzvshWXmf3Ci2M3T6Zm1Ojt49FtvzAiNthlxU3zdoT1Y03mcDuvJ+sVlJXU0zPYwtdLOhV1UrDL+zqe5jQbH/LWed0ArjW4CElTVCi68rszFJi4IXX1Q3jj6v+j7a5Ojuv+qoLTcbSF3yRVd1+h/VLEcmkpduo63b4AsIaA/XZ3lCUVmn1LYtj+sM0woAGXNKBfBWAZF1Womx7mekZkgI1475NlKaklBK33TAnoPHxbfzQaEcxfyaGBjyG+SRL0Nd37kxnBx2aHIXMfjVmN8iVeiXiP+MHqFHUZH/tnmxlx3Wi7e7jm41nDJ10vHj9mUZ6i5mAiP+Pm11Gg9lBn+wHDedGk6bTYunUNN1g958i4JbSQ/pR6alujjMPQWb+p+N2H0c5b5ovVheX6wZ9AZH/j+Nl1Zel/X9ExBGA0ijNLTOGnYvcIkozkDT++7v2YD2wI9nhH7E4qq8V2l5SSEonsoXQQKsTjI+vMfZajOfQrj2xll58+GLc3V0P48g/HAcDbGpmpdb6k+NeR2OrHbRHauY35rJxf9D3sLX2dKflplnf2f/ipbvnXFnWV1pgAk7ZqlJ2VWhvgWoEulSiH0YyiFJwoP8h/8TThwZlxY1njOKBGituk5ypEpU0bg3nI2d/yGf43w8u7jppn38fsdhiZY2sUv4J98PLtRXXPTEVXA6Q1T6idC/098F01OCl5UwVbSoFXw22NjR29lrMhrb+sWVgNXq6DpWpr7YaHzIzhQzrUZ5xPye1wFvnxZIK3Q/2u92mi3Ul1RrDvbH379j9p1euwgYr83Rqxkl8A1TIfo80adGtPXfvg4oCbfAukimQzqCutvGyxWLWt90ffz8tvP7OC54FF3t/yEGuJ5QjZgGtwcakEoW1MxrN/wF4JRK7UoAWaPgVDe62S6edzwDz9hjb5y55yepyWgs5yHueEANSy0/hbORZ8XSfljizzn1lf+8lD6dXgdcF9B/vJ+SYIZ32e8jLP+h2X5gr9hK/znOTpl7Zjrejs4hhu1uAZM1EKSA3M4BYXWsI2Ci121C4co+KsHcGb7oNkjcmZDH/KcQsjtWlMfPRA2Z2GF4e1h++wp5DjsZmSAe+F0aa5Lrg9mPRAPbH8BPbufLj9NIDtTx65XD4IDefuEu6hv0xaavroDeHx0fQYy4/YvbEItNYAfbH0yffa8rVAz6JUQ83wA8g9gYYRrYnlGOjBLTpYl47o+AdSNb/gaQrBf74DXsO0HXQQ+yBcCVSPhshnNgQ7zwIe56QYMVjzIu4clryXLssdZSRN67DvETmqPlDPigmc+5DYH8A6TtUXxzkHuugJvvqdHQ+5eyPrXGtISQx+wXq7eDZ5gfh1QdZ+L0zNfug+ewgmjwXgru/DyE2cQQmbS2n+l94fxtGwzB4bdWedYh2REqx8dJZGn8I3zjDfmPXR+itQ9cM5+qjsODWHtWBVgZ7CtRRUFP2Zp1DvIyFiLuka9gf6yLotTUR/a9e/vab5FaN9RB06/bD/k12WQc3wA8h1v6QJUpPKMdGCWjTxbx2RqP4P5B2pcCf/5jtr9lGD94BL3k4Jbum3Wp3TfgpavHdHGcgBkTxPCE88I1+gq6cMtGZKzg8t519KOWagGtkgEG9bhvjqQLA/SnK/Af48SVZvB0tH9K895KnYCcFAYl8PNcaIhK1Xwj5Rywd973ROt4VNMecWkpYXbAfDXrvd1h4axYccPf3Yawpjve+gVO5WfkHS7/Or/7eB2ziyYGO7rWn32gSVzqgG+k23Z+UWpZiCPndpgZ1503diVrTUz8wwu6buunjRVLEV1KBhm8IK68Gjhdk5X9derCoWmI5e51Q/t+NDc3Gm7r62i7Jba24AX4YMfSHYaL2hHJslIA2XcwxZBTtBpDwf8DuYRS6UkDjN70l2PmDsVGlCzu6h8vkJ4syU5KSFKkFhEPg0z4yAyEAvHuJD3wDgB1wKAX6CQDWQ1eb9FFGMGxvR7usnzj7jY31ek70h/BPrieD3Q3hc4xi+wNeyfHxQI2TdWZ2ixD46aO51hDzmfQLuPtLZD4f6Xy2eogbYIKzUQLadDHHk1GB/wM5Vwrh8ZsKTruMVaVNg4IATlRw5qlVVbCbtxIhMz0APU+8kDpwBYGbS5IPkd5pV5sRHTQQA8Z1etogMP37tar9zYMRoyf8E0hofsx2pqQKGPvAfpC0P7YXmv+kH7DiMVVHjjWCn0Sb9uVqZqNda4gB0sRgMBjMZw4zJHwYCWB/iP0f0P/KulLgjt/oM+MEacJK2MKDOjVuLiw1DZD1yI9CaRnheCvreeL/ytkfcB9o5a6Sy0bdZbmjjBwjg29G8H8CScFFFuQvQWR/8PZ/LIwaNBzv/VL2x1a51hCzUWqX4HwmxfyH8vlI57PVQ9wAE5yNEtCmi3ntjPqsUv4P2CUGGt5CA3f8RsdAvtA4AyH/68fG8jrrK3oUp5ZHLx8UzH+Ab6U9TwRnJQ580yBXTqlF7ZHVHwFcI2PGrsz8Qu0MUP7Xr/3oyDjH/lge1ufuKIeueQX2x5LXeqxQ84jZ/vP+d11dH+0sBiG2P6LUjFwBQXL8zMAlpxhca4j4TPoF3P0lMp+PdD5bPcQNMMHZKAFtupjXzqjvtsj/wcK4rCuFyemw/wx0PJqaulebvldpvEa0aomTzZ2dF7XGG1ayvbGR7xGBAe01EXiegF8LDnyjaxFwf+u+8PEcPhGXFVeQM+PgVH99OsjYdW2r7fHvXG8WFtPFqgPl2p99wWWh/4/6imp92P8HtehqPx455Ss+d761rjVEgIuYT3KID/TCutU06ruhcMln8AGotpvJgZ9Jgq5t9vx9t76xmUR7bCn/SJ/OYL4R9pvCI3J9s9k1H4IFvNPVrirNCe+hQSeRIKmF9fSG4nhOGq9dzE0EyPQHMyxM2JEl8vPRfOPnn280M34+Qm9dN1r1ZovFSDQZh6Zp/1nC8gqrPYIfBryFpOfX9zIeayDQq1hlZR+yjEP+0Vs6velG+7FiZt1QnI2PA8g380mO4CuHsR30JzeIb0s0A7BxUW9cXTq9+abF2NpkGIJNReIaCQ0RaloYcYIS34gSFIspKmuXVIhYeWA2WE04b3TNQgckQsnK6QNE2BLhPO4X6GJEchUbgoSjPLLXxAq4ifmUGFBvXV2wvfUaiWbD0N9QtjPuO+Y2VenX7H47ca1ygW2nsbGdJPXNRtc8BXrpR0Yw4lm7iIrDGvj6h6I5RkhHb6qI4Li1UimxY++jArLIfPowNl3MG5XRz4N3zmY1jByWqKwlTUp0oHd+3nGK8QMIeqWSw+axwMqY+ctyK/SSwkRUeuVQ7af9D1ITZAk8j+N3606hRSh0bkjgfXz5OXm4jvQuoduLtG76xHV4foj+z6XleVoSZ4yZMZLk4yst1zHXynPzl9WoAwJlRPHPQsP6Y7SVsEqNd1foh0PC8q6Iq535BeJ3aY3cqxmCL2/X7FHQM3Pvf9cdpaPJ+93aQrioJ84GumnrWVM6MOIXfdYM7ojaCzQkNGpEPrkBgXGzSj+6KL5GQkOkNQ0ilaDwG4kEhWJag3XqIVd5VhfHyGNV5Aswwk1av83SukNiycrpA0TUEud/7eikvZVQy2O2tjusC2Cu8gT+JX1NzCTYqLE4qm9mLADqT3PFFeTdCxCenJZqL/BbGlAJ5OGqXm+Qgs5MoQxgoLt01eA87S8VHiuYc3bcYN5yl//sa7sHLkb3LnlvK7MUYZ8OicJGCWjTxZxgmpTYzA+eanogdco3UVhLmiHRgd5RTsRF8Jq1r5j0eMly3jfmrpZwsE34glhOTryyK9nYIvBQD7f5wS0vO6rvTc08/zcTiYMmuv0hzlh4KUqCj6+0nCEE2GTF7GdYPcXkROiZcV9hPfnbdHBp0kZAtxnC8sI3Wn61c/2aS443S9475r4bKsYN19sBZTp9HgpWLFwuFGeDk+JWsrZ0KP9fL9+AnML94xkn7bMhGB4s9zjpngpCbxbI34bwGvFZdK+MpkHECYq+kTrcvvX2x+KQekdd/9Tfnn8/n6GHNLFkpfWBZkrYEr1TvjfIll0a7dbdnwwPk1zlCc5KXRMHCTZqLHmMB3PrSfd0IDh5tyniKoNjf0jUaph3TvWX1f3eGc9TzwyqFqihky/hZ+iyMgNGTgi88c0iCfj/6O68yxzhpoLe/o6+rjO0q5hEYqMEtOliTjBNSmSoBYf2tOMN819CEoc0mQO9817yUKraidoT3B+TStidvKExO/Wc2VyyV+1EcchgLBLuEWL4Hp/BdOI0C27t3uScY6Ynk2/Hvm+sNbFTnUL7Q1dJWAaGnD+0N55/yC5vIWI4afzxlZYzhMDBXvg55PdY63O+SN2ztxxGKhGXNyCqdu744nfpGgjLT06nTdfYTp8Yp3wDl++8XALp87pOwBuHKg+MQO8lsoF+33Jikk7Q57pzXVtVaxhGi3fUnMd6IkeRtienyuhhd0cJrgnDaMisjKYhxAlKPoImrHJR1FKKdeohR3lCbu2O5Lwa0+Opt56+xpNG3lImI9kVKX0QIWiJix4j0cNuk5dRHt41cZFoowblf2at36tI3ZVTbgrHUuHZHxHCtcoCZZCaU2N6MjUz1qepNdJLe9A5+h3yQlWlcTiiV9Syp+tED5ozg//9df9yv3fpCeOqLpHYKAFtupgTTZMwH0Ks0uQc6KX8T421mr6xmaknppqc1B3awV8F9gfx69sRU23j92NvJ5+YjuUkw8lwlAq416WrOjfA6xDhLaxffBiBqYSe4hbYH2HgUvQ+ddh3S2wnjT++0q5hf8yNdOs6fnYNdR3PT8tv5BaHLa+o2iX9bi9PkIcy1EOLlO/BtR+9QQqmzxtCQn53R1XTj2CklMoGumTLiVk6gemhiyXl14DdAGqjm7j6s9vRVV+YlnOGo1GRa5gvIhoip2kQcYKyj5BUOYFayrBOPRQoD+PEGU71p5aQ7LaCiGTp/xGsPjD/RhC2xMUh9cEupjrklId7TZwk2KgR8o/0Eh0D7qGu+vzMnMZwpYntD6lahfWSqaS39gec6tRDkeONwddDxOFyxiIBvHOqj4UjUU896LnrXUK3Y/tjvSSYJmE+iNikKT7QG0Bzj97+6kKV4/WEYP2FXhoIzsAp4ql71dtpL7Hgm7/suit24dsY3KjFuT1synDtjyWP8WvW+wvoI3azgUljPWn88ZWWM4SI119eeq59w0QMoYKv+ipzWm4YpMvLqfbIvFrIY9y7m95SAystufruS0drFdEFdybzAl+BV7QHOt0DujOVWAZiOs2tZk3pUP6/nk3QL5lgmN9RQo7+YTzBRmYIvLLW5OiHQ8Jr6IGSqyFymgYACiZI8PF/xI9AnzkJyqmlLOvUwyjKw3zmSVakD5zoqTTClkgtOJrSVQ5U2pV5GeXhXBM3iTVqrDwzfsNGJgq+tFaW6kdpC01gf/BqNQKyNZnLoAyyCdecf+LPCWTyQgEpWItkwaFKb3IsoNvnHZoq4gZTrWyoyIRhowS06WJOLE3CfBgxSFN4oDfk1mahAO7UlO3br4yeZUq0/3TWrS2iTyZP2ZRfMQsK4S5veeKmCb7ABd+8/AsOGOD2/SX04DdjV37Jjqxc+wP0icaraDCAx5e20+EJhRmDF8rw8ZWWM4SI958Gx7qPGtiIZYEnrdWW/wwKyyuudnDpzMtJWIPzj3RX0e0wTO6+KlvEkIDdI/MKy+lMqZc3DYPz/5j9p4uj+kJFhQ0GJYdd//b95qfPzacMjHFABVxt1db/DAuvAcURaoiEpjFKGBgTJuh5IfwG6LMgwSkptYzGOvVQoDz7K1G49pV5+4kdaM+jULIS+kAFZ7x/0XNC4pYIDami8BPCcJQHIH1NjCTWqAHq8CjolehWMu9qPc0e5+HaH6JajdQh0JbDJfRb1rxdueOU4+1T/e7tFbZJeBu0PxjnTzDimHS14vmP9ZJYmoT5MNaSJiU+0Eu9dRo0epI0aBqvMEvLwvO3obdOo0bfTRrONuoH0duD/w9jaSSZPKNnhbv87PdYzigJcyRaPTxgbDHC88nEzb5H40vAkvnrgUHbCQ/0nu54MgW6hLhOGoMrmE8fgeCM+77VqIRx4W/edoyD4Up08JWaG+0lGi+aLBbTxSbDA1CrwvKuSlR7ZONLwPfASHReBxWo6vgVva0CqKXxRzfUxcn0K+ziiLE4ja6spKSUPOOzFXE2PhIgQ8wnacBI8MhIn+dvP17RAA+UUv7h3uYzF003YYXp4MYL0TVBKQ0RaFpECcUJir5ZkUhQJKbogNuYT7EiVh5qyWNpUJ6/EXZJsCSWrFgfIltDRC0R/Lrg1u7jr+jxlQemIL4mDsCjmE8JQcg/ammG7e2m6WKz7gEyKGfcd62XkXOE7j7H+JJErXI2giz9YWk4TtwActd0wS04AZ/DRGiNpPV6u/JIA3sSG24UEVTZ0rjjhrooGc9/rJeNyigmEfhMpImVNpH5fKTz2eohboAJzkYJaNPFjDXpU+IzkSZW2kTm85HOZ6uHuAEmOBsloE0XM9akT4nPRJpYaROZz0c6n60e4gaY4GyUgDZdzFiTPiU+E2lipU1kPh/pfLZ6iBtggrNRAtp0MYOMYjAYDAaD+WRgBvgPA5uZGAwGg8Fgthpsf2AwGAwGg9lqsP2BwWAwGAxmq8H2BwaDwWAwmK0G2x8YDAaDwWC2Gmx/YDAYDAaD2Wqw/YHBYDAYDGarwfYHBoPBYDCYrQbbHxgMBoPBYLYabH9gMBgMBoPZarD9gcFgMBgMZqvB9gcGg8FgMJitBtsfGAwGg8Fgthpsf2AwGAwGg9laVlf/fxWh02CRY+tKAAAAAElFTkSuQmCC\"\u003e\u003c/p\u003e\n\u003cp\u003e\u003cimg 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\"\u003e\u003c/p\u003e"}],"fulltextSource":"","fullText":"","funders":[],"hasAdminPriorityOnWorkflow":false,"hasManuscriptDocX":false,"hasOptedInToPreprint":true,"hasPassedJournalQc":"","hasAnyPriority":true,"hideJournal":true,"highlight":"","institution":"","isAcceptedByJournal":false,"isAuthorSuppliedPdf":true,"isDeskRejected":"","isHiddenFromSearch":false,"isInQc":false,"isInWorkflow":false,"isPdf":false,"isPdfUpToDate":true,"isWithdrawnOrRetracted":false,"journal":{"display":true,"email":"[email protected]","identity":"researchsquare","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":true,"externalIdentity":"","sideBox":"","snPcode":"","submissionUrl":"/submission","title":"Research 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Amino acid residues residing at the interface play vital role in binding of SARS-CoV-2 CTD to hACE2. The detailed atomic level inves- tigation of interactions at binding interface of SARS-CoV-2 CTD/hACE2 provides indispensable information on better understanding of location for drug target. In the present work, we have studied the dynamical behaviour of the complex by ana- lyzing the molecular dynamics (MD) trajectories. The major interacting residues of SARS-CoV-2 CTD and hACE2 have been identified by analyzing the non-bonded interactions such as hydrogen bondings, salt bridges, hydrophobic interactions, van der Waals interactions etc. Umbrella sampling method has been used to estimate the binding free energy for in-depth understanding of binding mechanism between virus protein and host receptor. The binding free energy difference, key residues at the interface, important atomic interactions and contact surface areas have been compared with the molecular complex of SARS-CoV and hACE2. Relatively larger contact surface area, more non-bonded interactions as well as greater binding free energy provide the evidence for favorable binding of SARS-CoV-2 with hACE2 receptor than SARS-CoV.\u003c/p\u003e","manuscriptTitle":"Binding mechanism of SARS-CoV-2 spike protein with human ACE2 receptor","msid":"","msnumber":"","nonDraftVersions":[{"code":1,"date":"2020-09-08 18:52:17","doi":"10.21203/rs.3.rs-71923/v1","editorialEvents":[{"type":"communityComments","content":0}],"status":"published","journal":{"display":true,"email":"[email protected]","identity":"researchsquare","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":true,"externalIdentity":"","sideBox":"","snPcode":"","submissionUrl":"/submission","title":"Research Square","twitterHandle":"researchsquare","acdcEnabled":true,"dfaEnabled":false,"editorialSystem":"","reportingPortfolio":"","inReviewEnabled":false,"inReviewRevisionsEnabled":true}}],"origin":"","ownerIdentity":"5183e04f-7090-45ba-86c0-0e0370e8358f","owner":[],"postedDate":"September 8th, 2020","published":true,"recentEditorialEvents":[],"rejectedJournal":[],"revision":"","amendment":"","status":"posted","subjectAreas":[{"id":432642,"name":"Biophysics"}],"tags":[],"updatedAt":"2020-09-08T18:52:18+00:00","versionOfRecord":[],"versionCreatedAt":"2020-09-08 18:52:17","video":"","vorDoi":"","vorDoiUrl":"","workflowStages":[]},"version":"v1","identity":"rs-71923","journalConfig":"researchsquare"},"__N_SSP":true},"page":"/article/[identity]/[[...version]]","query":{"redirect":"/article/rs-71923","identity":"rs-71923","version":["v1"]},"buildId":"7rjqhiLT3MXkJMwkYKINL","isFallback":false,"isExperimentalCompile":false,"dynamicIds":[84888],"gssp":true,"scriptLoader":[]}