Prevalence Of Human Papillomavirus And Co-existent Sexually Transmitted Infections Among Female

Abstract Background: human papillomavirus is one of the most common sexually transmitted infections in the world, with a higher prevalence among young adults at the onset of sexual activity, Methods: prospective cross-sectional study were performed among 162 women aged between 18 and 73 years. For the DNA/HPV isolation, samples were collected and placed in the HC2 DNA Collection buffer (QIAGEN, CA, USA), and frozen at -20°C until processed. DNA/HPV extraction were performed by using QIAamp DNA Mini and Blood kit (QIAGEN, CA, USA) according to manufacturer instructions. Total DNA was isolated, eluted in 100 mL AE buffer and stored at 80˚C. Extracted DNA was quantified using a NanoVue unit (GE Healthcare Life Sciences, Little Chalfont, UK). Statistical analysis was performed using IBM SPSS® software version 23. Data were initially subjected to descriptive analysis, plus mean and standard deviation. Results: among the participants, 61.7% had DNA / HPV and 66.7% were users of illicit drugs and 59.3% were non-users, making them statistically significant. Among DNA/HPV positive users there was a higher proportion of sexually transmitted infections (STIs) (27.9%) compared to non-users (9.27%) (p> 0.05). Conclusion: the vulnerability of women to STIs and the high influence caused by the socioeconomic context in the course of these infections, the importance of public policies that establish appropriate strategies for their prevention, early diagnosis and treatment is emphasized, so that there is. The Research Ethics Committee of the University Hospital of the Federal University of Maranhão approved the project under the number CAAE 76328917.5.0000.5086, and informed consent was obtained from all subjects.