The use of a high-energy semiconductor laser (atcus-15) in treatment of background and precancerous diseases of cervix of the uterus

Purpose. To study the efficiency of laser destruction in treatment of background and precancerous diseases of cervix of the uterus. Full Text Purpose. To study the efficiency of laser destruction in treatment of background and precancerous diseases of cervix of the uterus.

and methods. 648 women in the age from 18 to 48 years with various pathologies of cervix of the uterus have been examined and treated. The standard algorithm has been used, including expanded colposcopy, bacterioscopic, cytologic and morphological examination, PCR diagnostics of genital infections. STD was observed in 87% of women, HPV was observed in 38% of cases according to results of PCR. In 68% of women suffering from STD a combination of infections was observed. Most frequently revealed was a combination of HPV, ureaplasmosis and bacterial vaginosis. All patients have received a complex stage- by-stage therapy. At the first stage antibacterial medications were used, taking into account the sensitivity of pathogen, as well as antiviral, antimycotics, local antiseptics, immunocorrectors. At the second stage, cervix of the uterus was subjected to laser destruction using the high-energy semi-conductor laser Atkus-15 (with the output power from 12 to 15 Watts) on an outpatient basis, on the 5-9th day of the menstrual cycle. At the third stage, in the postoperative period, all patients received the immunomodulating therapy with lycopede, with simultaneous exposure of the wound surface to low-intensive helium-neon laser irradiation.

and discussion. After the laser destruction of cervix of the uterus, the control examinations after 1, 2, and 3 months revealed a complete epithelization of cervix of the uterus and the absence of HPV sub- clinical attributes (colposcopic and cytologic) in 87% of women. 13% of patients demonstrated a flaccid epithelization which more frequently was revealed with background HPV and with a combination of various infections, requiring repeated complex treatment. Six months after treatment, in 2,5% of patients iodine-negative zones (relapse of HPV) were revealed that required repeated laser destruction. Conclusions. The use of the laser destruction method in patients of all age groups with a combination of background and inflammatory diseases of cervix of the uterus may help in future to prevent cancer development in cervix of the uterus, and can also be used to improve the reproductive health of women. About the authors L. V. Ivanova Military-medical Academy; Medical Academy. I.I. Mechnikov; Northwest Center for Laser Medicine Author for correspondence. Email: [email protected] Department of Obstetrics and Gynecology, Department of Minimally Invasive, Reconstructive Plastic, Laser Surgery of the Academy Russian Federation, Saint Petersburg; Saint Petersburg; Saint PetersburgЕ. V. Fedina Military-medical Academy; Medical Academy. I.I. Mechnikov; Northwest Center for Laser Medicine Email: [email protected] Department of Obstetrics and Gynecology, Department of Minimally Invasive, Reconstructive Plastic, Laser Surgery of the Academy Russian Federation, Saint Petersburg; Saint Petersburg; Saint PetersburgN. А. Kurganskaya Military-medical Academy; Medical Academy. I.I. Mechnikov; Northwest Center for Laser Medicine Email: [email protected] Department of Obstetrics and Gynecology, Department of Minimally Invasive, Reconstructive Plastic, Laser Surgery of the Academy Russian Federation, Saint Petersburg; Saint Petersburg; Saint Petersburg