The role of GnRH analogue therapy in the management of proximal fallopian tube occlusion

M R Masood, D Visvanathan, S M Sathanandan
Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology · 1999 · vol. 19(4) , pp. 417–420 · doi:10.1080/01443619964797 · PMID:15512346 · W2137387206
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⚙ AI-generated summary by claude@2026-06, 2026-06-10 ⓘ

GnRH analogue therapy for 3 months restored tubal patency in all 10 infertile women with proximal fallopian tube occlusion secondary to early endometriosis, with 4 achieving pregnancy post-treatment.

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Abstract

Ten infertile women were diagnosed as having bilateral or unilateral proximal tubal occlusion in the presence of minimal to mild endometriosis. They were treated with GnRH analogue for 3 months. The aim was to assess the usefulness of therapy in reversing the tubal block. Diagnosis was based on hysterosalpingography, laparoscopy and hysteroscopy. At completion of therapy tubal patency was confirmed by hysterosalpingography. Three patients had bilateral cornual block whereas seven had unilateral. All patients had achieved bilateral tubal patency immediately following therapy. Four women achieved pregnancy during a follow-up of 3-20 months. Our results show that if early endometriosis causes proximal tubal occlusion (without fibrosis) GnRH analogues may be considered as the first line of treatment.

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endometriosis

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References (38)

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