Scanning electron microscopy of endometrial cystic hyperplasia following exogenous oestrogen therapy and treatment with progestagen

Margaret H. Thom, F. E. Dische, Kelvin J.A. Davies, R. Senkus, John Studd
In: Journal of Obstetrics and Gynaecology · 1981 · vol. 2(1) , pp. 49–54 · doi:10.3109/01443618109067411 · W2226071756
article OA: closed CC0
View on OpenAlex View at publisher

Abstract

SummaryA patient who had developed endometrial cystic hyperplasia whilst receiving oestrogen therapy for climacteric symptoms was treated with a progestagen for two 3-week courses separated by I week. Scanning electron microscopy of the cystic hyperplasia showed regular columnar cells. Over one-third of these cells were covered by cilia and the remainder by long, branching microvilli. The first course of progestagen caused a progressive decrease in the number of cilia and shortening and fusing of the microvilli, until a flat ‘contraceptive pill-like’ atrophic endometrium was seen. After the second course of progestagen an atrophic endometrium was seen with large pleomorphic cells of unknown significance

My notes (saved in your browser only)

Citation neighborhood (sparse)

Too few in-corpus citations on either side for a chart; here are the lists.

Cites (2)

References (8)

Source provenance

openalex
last seen: 2026-06-10T17:14:06.276822+00:00
License: CC0 · commercial use OK