Indole sulfonamide modulators of progesterone receptors

DODGE JEFFREY ALAN, LOPEZ JOSE EDUARDO, BLEISCH THOMAS JOHN, CLARKE CHRISTIAN ALEXANDER, JONES SCOTT ALAN, LUGAR CHARLES WILLIS III, Muehl Brian Stephen, RICHARDSON TIMOTHY IVO, YEE YING KWONG, YU KUO-LONG
2011
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The authors disclose indole sulfonamide compounds and methods for their preparation, claiming use in medicaments to treat or prevent leiomyomas and endometriosis.

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Abstract

Disclosed is an indole sulphonamide compound of formula (I) wherein the substituents are as described in the disclosure. Also disclosed is a pharmaceutical composition comprising a compound of formula (I) and a method for preparing a compound of formula (I). Further disclosed is the use of a compound of formula (I) in the manufacture of a medicament for treating or preventing leiomyomas and endometriosis in a mammal.

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europepmc
last seen: 2026-07-13T06:13:37.491660+00:00